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Now showing items 736-755 of 1358
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Leptin, insulin like growth factor-I levels and histology-diagnosed placental malaria in an area characterized by unstable malaria transmission in central Sudan
(2017)Background: There are few published data on the association between leptin, insulin like growth factor-1 (IGF-1) and malaria during pregnancy. This study aimed to investigate maternal and umbilical cord leptin and IGF-1 ... -
Leveraging the Added Value of Experiential Co-Curricular Programs to Humanize Medical Education
(2021)Background: The aftermath of the 1910 Flexner report resulted in significant gaps in the structure of medical education. Experiential co-curricular opportunities can contribute to addressing these gaps. Purpose: To ... -
Ligament Tissue Engineering: The Anterior Cruciate Ligament
(2021)Abstract: Due to ongoing problems with reconstructive surgery and recent advancements in the field of musculoskeletal tissue engineering, regeneration of ligaments in general and of the anterior cruciate ligament (ACL) ... -
Lipids derived from Camel milk regulate NLRP3 inflammasome subunit-dependent inflammatory responses in human macrophages
(2021)Background: Camel milk is widely used for its reported anti-diabetic and health promoting effects. Lipids derived from the milk have also been shown to exhibit potent anti-inflammatory effects. The mechanism through which ... -
Lipoprotein(a) Induces Human Aortic Valve Interstitial Cell Calcification
(2017-03-30)Abstract: Lipoprotein(a), or Lp(a), significantly increased alkaline phosphatase activity, release of phosphate, calcium deposition, hydroxyapatite, cell apoptosis, matrix vesicle formation, and phosphorylation of signal ... -
Liraglutide Increases Serum Levels of MicroRNA-27b, -130a and -210 in Patients with Type 2 Diabetes Mellitus: A Novel Epigenetic E ect
(2020)Abstract: Liraglutide has shown favourable e_ects on several cardiometabolic risk factors, beyond glucose control. MicroRNAs (miRNAs) regulate gene expression, resulting in post-transcriptional modifications of cell ... -
A literature review and best practice advice for second and third trimester risk stratification, monitoring, and management of pre-eclampsia
(2021)Abstract: Pre-eclampsia is a multisystem disorder that typically affects 2%–5% of pregnant women and is one of the leading causes of maternal and perinatal morbidity and mortality, especially when the condition is of early ... -
Living Books: A Community Engagement Event to Encourage Open & Real Conversation
(2019-11)Inspired by Human Library which is designed to build a positive framework for conversations that can challenge stereotypes and prejudices through dialogue. Al Maktoum Medical Library designed a similar framework where ... -
LncRNA-Associated Genetic Etiologies Are Shared between Type 2 Diabetes and Cancers in the UAE Population
(2022)Abstract: Numerous epidemiological studies place patients with T2D at a higher risk for cancer. Many risk factors, such as obesity, ageing, poor diet and low physical activity, are shared between T2D and cancer; however, ... -
Long head of biceps brachii tendon and transverse humeral ligament morphometry and their associated pathology
(2020)Background: As a dynamic stabiliser and flexor of the glenohumeral joint, the long head of the biceps brachii tendon (LHBBT) is further stabilised by the retinacular activities of the transverse humeral ligament ... -
Long-Read Sequencing Improves the Detection of Structural Variations Impacting Complex Non-Coding Elements of the Genome
(2021)Abstract: The advent of long-read sequencing offers a new assessment method of detecting genomic structural variation (SV) in numerous rare genetic diseases. For autism spectrum disorders (ASD) cases where pathogenic ... -
Long-Term Recurrent Intramedullary Arachnoid Cyst: Case Report and Literature Review
(2023)Objectives: This article reports the management of a case of a 32-year-old male who presented with progressive weakness in the lower limbs and spastic paraparesis secondary to an intramedullary arachnoid cyst (IMAC). For ... -
Loss of pulp vitality following preparation of vital teeth for crowns/FDPs restorations for at least 5 years of follow up period: A Systematic Review and Meta-Analysis
(2022)Background: Loss of pulp vitality is a common biological complication after full coverage indirect restorations, and dental practitioners should be aware of the contributing factors to achieve best treatment outcome. ... -
Low Birth Weight Prevalence in Children Diagnosed with Neurodevelopmental Disorders in Dubai
(2021)Abstract: The aim of this study is to evaluate the prevalence of low birth weight and other perinatal risk factors in children diagnosed with neurodevelopmental disorders. This is one of the first studies in the Arabian ... -
Lung Epithelial Cells from Obese Patients Have Impaired Control of SARS-CoV-2 Infection
(2023)Abstract: Obesity is known to increase the complications of the COVID-19 coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms of SARSCoV-2 infection ... -
M1 Polarization Markers Are Upregulated in Basal-Like Breast Cancer Molecular Subtype and Associated With Favorable Patient Outcome
(2020)Background: Breast cancer heterogeneity is an essential element that plays a role in the therapy response variability and the patient’s outcome. This highlights the need for more precise subtyping methods that focus not ... -
M680I/M694V Heterozygous Mutation in Early Onset Familial Mediterranean Fever
(2021)Abstract: Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disorder affecting individuals with biallelic pathogenic mutations in the MEFV gene. The disease is characterized by recurrent attacks of fever ... -
The magnitude and effect of work-life imbalance on cognition and affective range among the non-western population: A study from Muscat
(2022)Abstract: The temporal relationship between work-life balance/imbalance, occupational burnout, and poor mental health outcomes have been widely explored. Little has been forthcoming on cognitive functioning among those ... -
Maintenance of neutralizing antibodies over ten months in convalescent SARS-CoV-2 afflicted patients
(2021)Abstract Knowledge of the level and duration of protective immunity against SARS-CoV-2 after primary infection is of crucial importance for preventive approaches. Currently, there is a lack of evidence on the persistence ... -
Male infertility: A proximate look at the advanced glycation end products
(2020)Abstract: Advanced glycation end products (AGEs) are products of cascades of non-enzymatic glycosylation. They are formed over a period of hours to days, depending on the protein lifetime. AGEs acts by independently ...