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1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice
(2019)More than 90% of human pancreatic cancers carry the oncogenic mutant of Ki-RAS and their growth depends on its downstream kinase PAK1, mainly because PAK1 blocks the apoptosis of cancer cells selectively. We developed a ... -
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries
(2018)Background: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic ... -
AFM-compatible microfluidic platform for affinity-based capture and nanomechanical characterization of circulating tumor cells
(2020)Abstract: Circulating tumor cells (CTCs) carried by the patient’s bloodstream are known to lead to the metastatic spread of cancer. It is becoming increasingly clear that an understanding of the nanomechanical characteristics ... -
Analysis of blood donor pre-donation deferral in Dubai: Characteristics and reasons
(2017)Background: To ensure an adequate and safe blood supply, it is crucial to select suitable donors according to stringent eligibility criteria. Understanding the reasons for donor deferral can help in planning more efficient ... -
Analysis of risk factors, presentation, and in-hospital events of very young patients presenting with ST-elevation myocardial infarction
(2017-02-05)Introduction: In the Indian subcontinent and Arab Gulf, coronary artery disease is affecting younger persons at greater rates. Few studies have focused on young ST-elevation myocardial infarction (STEMI) patients in these ... -
An anatomical investigation of the carotid canal
(2017)Background: The carotid canal (CC) located in the petrous temporal bone trans-mits the internal carotid artery, internal carotid venous plexus and sympathetic nerve plexus from the neck into the cranial cavity. It is an ... -
Anterior teeth root inclination prediction derived from digital models: A comparative study of plaster study casts and CBCT images Mahmoud Dastoori MSc, University College London, 2007 DDS, Ajman
(2017-08)Aim: To assess the accuracy of digital models generated using commercially available software to predict anterior teeth root inclination characteristics and compare the results to relevant data obtained from CBCT images. ... -
Anterior teeth root morphology prediction as derived from digital models: A comparative study of plaster study casts and natural teeth from dry skulls
(2018)Aim: To assess the accuracy and reliability of the digital images of dental models generated by specific commercially available software in predicting root morphology characteristics in comparison to the corresponding ... -
An anthropometric evaluation of the scapula, with emphasis on the coracoid process and glenoid fossa in a South African population
(2019)Abstract: The exact dimensions of the scapula, including the coracoid process and glenoid fossa, are fundamental in the patho-mechanics of the glenohumeral joint (GHJ); as these structures act as initiators of shoulder ... -
Are asthma and airway allergy associated with increased root resorption following orthodontic treatment? A systematic review
(2020)Aim: Asthma and airway allergy have been implicated with root resorption development following orthodontic treatment. The objective of this study was to investigate systematically the relevant literature. Materials ... -
An arthroscopic evaluation of the anatomical “critical zone”
(2017)Background: The “critical zone”, a region of speculated vascularity, is situated approximately 10 mm proximal to the insertion of the supraspinatus tendon. De-spite its obvious role as an anatomical landmark demarcator, ... -
Artificial intelligence for precision medicine in neurodevelopmental disorders
(2019)Abstract: The ambition of precision medicine is to design and optimize the pathway for diagnosis, therapeutic intervention, and prognosis by using large multidimensional biological datasets that capture individual variability ... -
Assessment Of Anxiety Levels Among Patients Attending Oral Surgery Department At Hamdan Bin Mohammed College Of Dental Medicine In United Arab Emirates
(2019)Objectives: To assess the dental anxiety levels among patients attending Oral Surgery department at Hamdan Bin Mohammed Dental Clinics (HBMCDM) and to identify factors influencing dental anxiety level among the patients ... -
Assessment of the Knowledge of United Arab Emirates Dentists of Child Maltreatment, Protection and Safeguarding
(2016-08)Background: Child safeguarding, governed by international, national and local laws, is the responsibility of all members of society. Members of the dental team are in a unique position to recognize Child Abuse and Neglect ... -
Assessment of The Quality Of Endodontic Retreatment On A Postgraduate Endodontic Clinic In Hbmcdm (2008-2015)
(2017-08)INTRODUCTION The main objective of endodontic therapy is to prevent or cure apical periodontitis by shaping and cleaning the endodontic pulp space and provide three dimensional obturation. However, shaping and cleaning ... -
Association between type II diabetes and apical periodontitis: a critical review and before/after study on the outcome of endodontic treatment in an emirati adult population
(2020)The work presented here consists of two distinct parts. Part 1: A Critical Review of the literature Background: Diabetes has been found to be associated with increased risk of infections, impaired immune response ... -
Association of IMMP2L deletions with autism spectrum disorder: A trio family study and meta-analysis
(2018)Abstract: IMMP2L, the gene encoding the inner mitochondrial membrane peptidase subunit 2- like protein, has been reported as a candidate gene for Tourette syndrome, autism spectrum disorder (ASD) and additional ... -
Attitude and Use of Rubber Dam During Endodontic Procedures in the United Arab Emirates
(2017-08)Introduction: Rubber dam is an essential adjunct in endodontic treatment that was introduced as early as 1864. It prevents swallowing of medicament, instruments and irrigating solutions, debris and retracts soft tissue. ... -
Attitude of Ajman University Dental Undergraduate Students and Residents to Vital and Non-Vital Bleaching
(2017)The management of tooth discoloration has become a challenge, especially as people are keeping their teeth for longer. Discoloration can affect both primary and secondary teeth alike. The causes of tooth discoloration are ... -
Between-ward disparities in colorectal cancer incidence and screening in Washington DC
(2015-09-04)Abstract This study aims to investigate the incidence and determinants of colorectal cancer (CRC) and its screening in District of Columbia (DC), and identify modifiable risk factors. Data (2000–2009) from the DC Cancer ...