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Now showing items 1-20 of 1457
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1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice
(2019)More than 90% of human pancreatic cancers carry the oncogenic mutant of Ki-RAS and their growth depends on its downstream kinase PAK1, mainly because PAK1 blocks the apoptosis of cancer cells selectively. We developed a ... -
A 12‑month prospective real‑life study of opicapone efficacy and tolerability in Emirati and non‑White subjects with Parkinson’s disease based in United Arab Emirates
(2023)Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and the condition is complicated by the emergence of wearing of/motor fuctuations with levodopa treatment after a variable period. ... -
2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2020)Abstract: In March 2020, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. At the genus rank, 20 new ... -
2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2021)Abstract: In March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by ... -
2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2022-11)Abstract: In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by ... -
A 24‑month retrospective study of preformed metal crowns: the Hall technique versus the conventional preparation method
(2020)Purpose: Conventional and Hall Technique (HT) Preformed Metal Crowns (PMCs) are used for treatment of carious primary molars. The aim was to evaluate the clinical and radiographic success of conventional and HT PMCs in ... -
3D bioprinting for in vitro models of oral cancer: Toward development and validation
(2021)Abstract The tumor microenvironment (TME) of oral carcinomas has highly complex contents and a dynamic nature which is difficult to study using oversimplified two-dimensional (2D) cell culture systems. By contrast, three ... -
3D Printing of Dental Prostheses: Current and Emerging Applications
(2023)Abstract: Revolutionary fabrication technologies such as three-dimensional (3D) printing to develop dental structures are expected to replace traditional methods due to their ability to establish constructs with the ... -
3D superimposition of dental casts based on coloured landmark detection using combined computer vision and 3D computer graphics techniques
(2019)Abstract: The aim of this study was to evaluate the validity and reliability of three-dimensional (3D) landmark-based palatal superimposition of digital dentalmodels using the customized software Ortho Mechanics Sequential ... -
The ABC-Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study
(2024-02)Abstract: Background: The ABC-stroke score is a risk scheme for prediction of stroke or systemic embolism (SE) in atrial fibrillation (AF). This study sought to examine whether the score could be useful in predicting ... -
Abrasion: A Common Dental Problem Revisited
(2017-02-28)Abstract: Dental abrasion is most commonly seen at the cervical necks of teeth, but can occur in any area, even inter-dentally from vigorous and incorrect use of dental floss. Acid erosion has been implicated in the ... -
Accuracy and reliability of landmark- based, surface- based and voxel- based 3D cone- beam computed tomography superimposition methods
(2017)Objectives: To evaluate and compare the accuracy and reliability of 3 different methods of three- dimensional cone- beam computed tomography scans (3D CBCTs) superimpositions: landmark- based, surface- based and voxel- ... -
Accuracy of three-dimensional dental resin models created by fused deposition modeling, stereolithography, and Polyjet prototype technologies: A comparative study
(2018)Objectives: The aim of this study was to assess the dimensional accuracy of fused deposition modeling (FDM)–, Polyjet-, and stereolithography (SLA)–produced models by comparing them to traditional plaster casts. Materials ... -
Accuracy of three-dimensional printed guide plate for indirect bracket placement: one-piece verses segmented, an in Vitro study
(2022)Background: An accurate placement of brackets is a key element of the comprehensive treatment process of orthodontics to achieve an ideal occlusion. Orthodontic brackets can be directly placed on tooth surfaces or ... -
ACE2 polymorphisms impact COVID-19 severity in obese patients
(2022-12)Abstract: A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. ... -
Acid erosion: an increasingly relevant dental problem. Risk factors, management and restoration
(2017)Abstract: A review of risk factors and management of acid erosion. Particular emphasis is placed on the use of direct composite as a reversible and relatively straightforward restorative option. -
Action of 1,25(OH)2D3 on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma
(2020)Background: Airway fibroblasts are major contributors to the histopathological feature of airway remodeling in asthma by their implication in the cell invasiveness and profibrogenic secretory phenotype observed in ... -
Activity-Dependent Non-Coding RNA MAPK Interactome of the Human Epileptic Brain
(2023)Abstract: The human brain has evolved to have extraordinary capabilities, enabling complex behaviors. The uniqueness of the human brain is increasingly posited to be due in part to the functions of primate-specific, ... -
Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients
(2020)Abstract: Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population. Methods: A retrospective study ... -
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries
(2018)Background: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic ...
