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Natural compound catechol induces DNA damage, apoptosis, and G1 cell cycle arrest in breast cancer cells
(2020)Abstract: Targeting cell cycle and inducing DNA damage by activating cell death pathways are considered as effective therapeutic strategy for combating breast cancer progression. Many of the naturally known small molecules ... -
Negative Effects On Cancer Care Due To COVID-19 Implications: Observations From A Cancer Center In The UAE
(2020)Abstract: In 2019, the World Health Organization declared the novel coronavirus disease (COVID-19) to be a public health emergency of international concern that rapidly escalated to pandemic status in 2020 (1). As of ... -
Neural Processing of Dynamic Animated Social Interactions in Young Children With Autism Spectrum Disorder: A High-Density Electroencephalography Study
(2019-08-22)Background: Atypical neural processing of social visual information contributes to impaired social cognition in autism spectrum disorder. However, evidence for early developmental alterations in neural processing of ... -
Neuroprotective effects of Bhilawanol and Anacardic acid during glutamate-induced neurotoxicity
(2021)Abstract: Bhilawanol (Bh) and anacardic acid (AA) are two lipid-soluble compounds mostly found in the nut of Semecarpus anacardium (SA). This herb has many medicinal properties including enhancing learning and memory, yet ... -
No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses
(2019)Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the family Flaviviridae. However, apart from a single case of vertical transmission, natural routes of EqHV transmission ... -
Non syndromic familial hypodontia - a case series
(2018)Aim: The aim of this case report is to discuss the features of non-syndromic familial hypodontia, which was noted in three siblings who had an unremarkable medical history. Summary: Congenital absence of teeth is ... -
Non-coronary atherosclerotic cardiovascular disease in patients with familial hypercholesterolaemia
(2020)Objective: Familial hypercholesterolaemia (FH) is a common autosomal dominant inherited disease, affecting 1 in 200 - 500 individuals worldwide. FH is characterized by elevated circulating low-density lipoprotein cholesterol ... -
Non-withdrawal of beta blockers in acute decompensated chronic and de novo heart failure with reduced ejection fraction in a prospective multicentre study of patients with acute heart failure in the Middle East
(2017-05-17)Objectives: Beta blockers reduce mortality in heart failure (HF). However, it is not clear whether they should be temporarily withdrawn during acute HF. Design: Analysis of prospectively collected data. Setting: The ... -
Noninvasive Ventilation in the Management of Respiratory Failure Due to COVID-19 Infection: Experience From a Resource-Limited Setting
(2022)Objective: To study the role of noninvasive ventilation (NIV) in Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV2) related acute respiratory failure (C-ARF). Patients and Methods: Patients with C-ARF ... -
Nootkatone confers hepatoprotective and anti-fibrotic actions in amurine model of liver fibrosis by suppressing oxidative stress, inflammation, and apoptosis
(2017-11-20)Abstract: In this study, the hepatoprotective and anti-fibrotic actions of nootkatone (NTK) were investigated using carbon tetrachloride (CCl4)-induced liver fibrosis in mice. CCl4 administration elevated serum aspartate ... -
A novel 6D-approach to radically transform undergraduate medical education: preliminary reflections from MBRU
(2018-12)Background: Designers of undergraduate medical education (UME) need to address the exponentially expanding volume and variability of scientific knowledge, where by didactic teaching techniques need to be augmented by ... -
A novel HRM assay for the simultaneous detection and differentiation of eight poxviruses of medical and veterinary importance
(2017-02-20)Abstract: Poxviruses belonging to the Orthopoxvirus, Capripoxvirus and Parapoxvirus genera share common host species and create a challenge for diagnosis. Here, we developed a novel multiplex PCR method for the simultaneous ... -
A Novel Method to Evaluate Precision of Optical Implant Impressions with Commercial Scan Bodies—An Experimental Approach
(2017)Purpose: Optical transfer is realized with system-specific transfer posts (scan bodies) mounted on dental implants or on implant analogs. This study presents a novel algorithm for creation of geometry on the surface of ... -
Novel mutations in actionable breast cancer genes by targeted sequencing in an ethnically homogenous cohort
(2019)Background: Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway, and particularly important for early detection and cancer prevention. The purpose of this study was to ... -
Novel mutations in actionable breastcancer genes by targeted sequencing in anethnically homogenous cohort
(2019)Background:Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway,and particularly important for early detection and cancer prevention. The purpose of this study was to explore ... -
Nutritional and micronutrient status of adolescent schoolgirls in eastern Sudan: A cross-sectional study
(2017)Background: Adolescents, especially girls, are susceptible to malnutrition and their diet must be adequate to support their very rapid growth and development. Currently, there is little published data on the nutritional ... -
Obstructive Sleep Apnoea Hypopnoea Syndrome and the Cranio Facio-hyoid Morphology in Adults: Linear and Angular Measurements
(2015-11)Abstract: The gold standard for diagnosis of Obstructive Sleep Apnoea Hypopnoea Syndrome is the polysomnography which is expensive and time consuming. The development of alternative diagnostic methods would therefore ... -
Occlusal Outcome Assessment of Orthodontic Treatments Performed at An Educational Institute in Dubai
(2016)Aim: To assess occlusal outcome of comprehensive orthodontic treatments performed by postgraduate students at an educational institute in Dubai. Materials and Methods: Consecutive patients’ files, including dental ... -
Occupational Health of Frontline HealthcareWorkers in the United Arab Emirates during the COVID-19 Pandemic: A Snapshot of Summer 2020
(2021)Abstract: The study aim was to understand the availability of personal protective equipment (PPE) and the levels of anxiety, depression, and burnout of healthcare workers (HCWs) in the United Arab Emirates (UAE). This ... -
One-year all-cause mortality risk among atrial fibrillation patients in Middle East with and without diabetes: The Gulf SAFE registry
(2020)Background: Atrial fibrillation (AF) poses a great risk of mortality, especially when associated with diabetes mellitus (DM). OBJECTIVES: We aimed to investigate the rate and risk factors for mortality among AF patients ...