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YY1 directly interacts with myocardin to repress the triad myocardin/SRF/CArG box‑mediated smooth muscle gene transcription during smooth muscle phenotypic modulation
(2020)Summary : Yang 1 (YY1) regulates gene transcription in a variety of biological processes. In this study, we aim to determine the role of YY1 in vascular smooth muscle cell (VSMC) phenotypic modulation both in vivo and ... -
α-Bisabolol Mitigates Colon Inflammation by Stimulating Colon PPAR-γ Transcription Factor: In Vivo and In Vitro Study
(2022)Background: The incidence and prevalence of inflammatory bowel disease (IBD, Crohn’s disease, and ulcerative colitis) are increasing worldwide. The etiology of IBD is multifactorial, including genetic predisposition, ... -
β-Blocker therapy prior to admission for acute coronary syndrome in patients without heart failure or left ventricular dysfunction improves in-hospital and 12-Month Outcome: Results from the GULF-RACE 2 (Gulf Registry of Acute Coronary Events-2)
(2017-11-14)Background: The prognostic impact of b-blockers (BB) in acute coronary syndrome (ACS) patients without heart failure (HF) or left ventricular dysfunction is controversial, especially in the postreperfusion era. We sought ...