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Now showing items 845-864 of 1358
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Nootkatone confers hepatoprotective and anti-fibrotic actions in amurine model of liver fibrosis by suppressing oxidative stress, inflammation, and apoptosis
(2017-11-20)Abstract: In this study, the hepatoprotective and anti-fibrotic actions of nootkatone (NTK) were investigated using carbon tetrachloride (CCl4)-induced liver fibrosis in mice. CCl4 administration elevated serum aspartate ... -
A novel 6D-approach to radically transform undergraduate medical education: preliminary reflections from MBRU
(2018-12)Background: Designers of undergraduate medical education (UME) need to address the exponentially expanding volume and variability of scientific knowledge, where by didactic teaching techniques need to be augmented by ... -
A novel HRM assay for the simultaneous detection and differentiation of eight poxviruses of medical and veterinary importance
(2017-02-20)Abstract: Poxviruses belonging to the Orthopoxvirus, Capripoxvirus and Parapoxvirus genera share common host species and create a challenge for diagnosis. Here, we developed a novel multiplex PCR method for the simultaneous ... -
Novel Markers in Pediatric Acute Lymphoid Leukemia: The Role of ADAM6 in B Cell Leukemia
(2021)Background: The extensive genetic heterogeneity found in the B cell precursor acute lymphoblastic leukemia (BCP-ALL) subtype of childhood ALL represents a potential repository of biomarkers. To explore this potential, ... -
A Novel Method to Evaluate Precision of Optical Implant Impressions with Commercial Scan Bodies—An Experimental Approach
(2017)Purpose: Optical transfer is realized with system-specific transfer posts (scan bodies) mounted on dental implants or on implant analogs. This study presents a novel algorithm for creation of geometry on the surface of ... -
Novel mutations in actionable breast cancer genes by targeted sequencing in an ethnically homogenous cohort
(2019)Background: Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway, and particularly important for early detection and cancer prevention. The purpose of this study was to ... -
Novel mutations in actionable breastcancer genes by targeted sequencing in anethnically homogenous cohort
(2019)Background:Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway,and particularly important for early detection and cancer prevention. The purpose of this study was to explore ... -
A novel reconstructive approach of the lumbar vertebral column from 2D MRI to 3D models
(2022-11)Introduction: Low back pain (LBP), arising from the lumbar vertebral column (LVC), is a global burden, ranking highest in terms of disability. In the United Arab Emirates (UAE), there is a high prevalence of LBP in the ... -
Nutritional and micronutrient status of adolescent schoolgirls in eastern Sudan: A cross-sectional study
(2017)Background: Adolescents, especially girls, are susceptible to malnutrition and their diet must be adequate to support their very rapid growth and development. Currently, there is little published data on the nutritional ... -
Obesity and female infertility
(2023)Abstract: Infertility is a significant global health issue, with a negative impact on people's wellbeing and human rights. Despite the longstanding association between obesity and infertility, there remains uncertainty, ... -
Obesity and nonalcoholic fatty liver disease in type 1 diabetes mellitus patients
(2022-11)Introduction: Assessed the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with type 1 diabetes mellitus (T1DM). They included 15 children with T1DM and obesity, 34 children with T1DM but no obesity and ... -
The "obesity paradox" in patients with atrial fibrillation: Insights from the Gulf SAFE registry
(2022-11)Abstract: Background: The prognostic impact of obesity on patients with atrial fibrillation (AF) remains under-evaluated and controversial. Methods: Patients with AF from the Gulf Survey of Atrial Fibrillation Events ... -
Obsessive-Compulsive Symptoms in an Adolescent with Intellectual Disability
(2022)Abstract: Individuals with intellectual disability (ID) experience various psychiatric comorbidities including anxiety, depression, and obsessive-compulsive disorder (OCD) in a rate that is equivalent or higher than ... -
Obstructive Sleep Apnoea Hypopnoea Syndrome and the Cranio Facio-hyoid Morphology in Adults: Linear and Angular Measurements
(2015-11)Abstract: The gold standard for diagnosis of Obstructive Sleep Apnoea Hypopnoea Syndrome is the polysomnography which is expensive and time consuming. The development of alternative diagnostic methods would therefore ... -
Occlusal Outcome Assessment of Orthodontic Treatments Performed at An Educational Institute in Dubai
(2016)Aim: To assess occlusal outcome of comprehensive orthodontic treatments performed by postgraduate students at an educational institute in Dubai. Materials and Methods: Consecutive patients’ files, including dental ... -
Occupational Exposure to Solar Radiation and the Eye: A Call to Implement Health Surveillance of Outdoor Workers
(2023)Abstract: Globally, hundreds of millions of outdoor workers are exposed to solar radiation (SR) for most of their work. Such occupational exposure is known to induce various adverse health effects on the eyes, mainly ... -
Occupational Health of Frontline HealthcareWorkers in the United Arab Emirates during the COVID-19 Pandemic: A Snapshot of Summer 2020
(2021)Abstract: The study aim was to understand the availability of personal protective equipment (PPE) and the levels of anxiety, depression, and burnout of healthcare workers (HCWs) in the United Arab Emirates (UAE). This ... -
oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR‑Cas9 edited cerebral organoids
(2023)Abstract: Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged in the identification of critical cell types perturbed by genetic risk variants in common, ... -
Omics and Male Infertility: Highlighting the Application of Transcriptomic Data
(2022)Abstract: Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples. Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, ... -
On family-centred and child-centred care - And the moral distress therein
(2022)On family-centred and child-centred care - And the moral distress therein