Browsing by Title
Now showing items 814-833 of 1358
-
Muscle sympathetic nerve activity peaks in the first trimester in healthy pregnancy: a longitudinal case study
(2017-07-03)Objective and methods: Muscle sympathetic nerve activity and baroreflex sensitivity were examined at rest before, during (weeks 6, 11, 17, 22, 25, 33 and 36) and after a normotensive pregnancy. Results: Muscle sympathetic ... -
Muscle sympathetic nerve activity-coupled changes in brain activity during sustained muscle pain
(2018-02-07)Introduction: Long-lasting experimental muscle pain elicits divergent muscle sympathetic responses, with some individuals exhibiting a persistent increase in muscle sympathetic nerve activity (MSNA), and others a decrease. ... -
Mutaba’ah—Mother and Child Health Study: protocol for a prospective cohort study investigating the maternal and early life determinants of infant, child, adolescent and maternal health in the United Arab Emirates
(2019)Introduction: Early life exposures, particularly environmental and parental lifestyle factors, have a major influence on children’s health and development. Due to increasing interest in the early life developmental origins ... -
The mutagenic effect of tobacco smoke on male fertility
(2021)Abstract: Despite the association between tobacco use and the harmful effects on general health as well as male fertility parameters, smoking remains globally prevalent. The main content of tobacco smoke is nicotine and ... -
Mutational Landscape of Autism Spectrum Disorder Brain Tissue
(2022)Abstract: Rare post-zygotic mutations in the brain are now known to contribute to several neurodevelopmental disorders, including autism spectrum disorder (ASD). However, due to the limited availability of brain tissue, ... -
Mutations in RAB39B in individuals with intellectual disability, autism spectrum disorder, and macrocephaly
(2017-11-09)Background: Autism spectrum disorder (ASD), a developmental disorder of early childhood onset, affects males four times more frequently than females, suggesting a role for the sex chromosomes. In this study, we describe ... -
Mystery of fatal ‘staggering disease’ unravelled: novel rustrela virus causes severe meningoencephalomyelitis in domestic cats
(2023)Introduction: ‘Staggering disease’ is a neurological disease entity considered a threat to European domestic cats (Felis catus) for almost five decades. However, its aetiology has remained obscure. Rustrela virus (RusV), ... -
N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients
(2022)Abstract: Despite the growing number of the vaccinated population, COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global health burden. Obesity, a metabolic syndrome affecting ... -
NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs
(2022)Abstract: Systemic sclerosis (SSc) is an immune disorder characterized by diffuse fibrosis and vascular abnormalities of the affected organs. Although the etiopathology of this disease is largely unknown, endothelial ... -
Nano-targeting vascular remodeling in cancer: Recent developments and future directions
(2022)Abstract: Tumor growth and progression are strictly dependent on the adequate blood supply of oxygen and nutrients. The formation of new blood vessels and vascular networks is essential to ensure this demand. Blood vessels ... -
A national study on the resilience of community pharmacists in Lebanon: a cross‑sectional survey
(2022)Background: Community pharmacists are among the most accessible healthcare professionals and are likely to experience the full brunt of public health crises. In Lebanon, the COVID-19 pandemic, added to a severe economic ... -
Natural compound catechol induces DNA damage, apoptosis, and G1 cell cycle arrest in breast cancer cells
(2020)Abstract: Targeting cell cycle and inducing DNA damage by activating cell death pathways are considered as effective therapeutic strategy for combating breast cancer progression. Many of the naturally known small molecules ... -
Negative Effects On Cancer Care Due To COVID-19 Implications: Observations From A Cancer Center In The UAE
(2020)Abstract: In 2019, the World Health Organization declared the novel coronavirus disease (COVID-19) to be a public health emergency of international concern that rapidly escalated to pandemic status in 2020 (1). As of ... -
Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models
(2021)Abstract: Nerolidol (NED) is a naturally occurring sesquiterpene alcohol present in various plants with potent anti-inflammatory e_ects. In the current study, we investigated NED as a putative anti-inflammatory compound ... -
Neural Processing of Dynamic Animated Social Interactions in Young Children With Autism Spectrum Disorder: A High-Density Electroencephalography Study
(2019-08-22)Background: Atypical neural processing of social visual information contributes to impaired social cognition in autism spectrum disorder. However, evidence for early developmental alterations in neural processing of ... -
Neuroprotective effects of Bhilawanol and Anacardic acid during glutamate-induced neurotoxicity
(2021)Abstract: Bhilawanol (Bh) and anacardic acid (AA) are two lipid-soluble compounds mostly found in the nut of Semecarpus anacardium (SA). This herb has many medicinal properties including enhancing learning and memory, yet ... -
NeuroSCORE is a genome‑wide omics‑based model that identifes candidate disease genes of the central nervous system
(2022)Abstract: To identify candidate disease genes of central nervous system (CNS) phenotypes, we created the Neurogenetic Systematic Correlation of Omics-Related Evidence (NeuroSCORE). We identified five genome-wide metrics ... -
New Onset Diabetes Mellitus in COVID-19: A Scoping Review
(2024)Background: Higher education institutions need to put change management as a pivotal part of their strategy. The challenge is to effectively contextualize existing change management models to the respective work environment. ... -
New World camelids are sentinels for the presence of Borna disease virus
(2021)Abstract: Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured ... -
Nigella sativa and its chemical constituents: pre clinical and clinical evidence for their potential anti SARS CoV 2 effects
(2023)Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 500 million reported cases of COVID-19 worldwide with relatively high morbidity and mortality. Although global vaccination drive has ...