Browsing by Title
Now showing items 536-555 of 1358
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Fracture resistance of porcelain veneered zirconia crowns with exposed lingual zirconia for anterior teeth after thermal cycling: An in vitro study
(2015-01-30)Statement of problem: In some clinical conditions minimally invasive complete crown tooth preparations are indicated. This is especially true when gross removal of tooth structure would weaken the remaining tooth or violate ... -
From black to white: A roadmap to containing the rise of candidiasis amidst COVID-19 and mucormycosis in India
(2021)Abstract: With numbers of active COVID-19 cases in India falling in recent weeks and the healthcare system finally showing signs of coping with the mucormycosis epidemic, several new reports of COVID-19 cases linked to ... -
Functional Mimicry of Eukaryotic Actin Assembly by Pathogen Effector Proteins
(2022)Abstract: The actin cytoskeleton lies at the heart of many essential cellular processes. There are hundreds of proteins that cells use to control the size and shape of actin cytoskeletal networks. As such, various pathogens ... -
Gaps and opportunities for nutrition research in relation to non-communicable diseases in Arab countries: Call for an informed research agenda
(2017-07-31)Abstract: Effective public health nutrition interventions are needed to curb the escalating prevalence of non-communicable diseases (NCDs) in many Arab countries. In order to generate the scientific evidence needed for the ... -
Gender equity in rheumatology leadership in the Asia-Pacific
(2022-08)Objectives: This study aimed to explore gender equity in rheumatology leadership in the Asia-Pacific region as represented by the member national organizations (MNOs) of the Asia-Pacific League of Associations for ... -
Gender-specific Reference Range for Serum Leptin in Omani Population
(2023)Objectives: Leptin is a hormone that contributes to glucose homeostasis and food intake regulation via its action on the hypothalamus. Leptin level increases with obesity and overfeeding and decreases with energy deficiency. ... -
Genetic analysis of imported dengue virus strains by Iranian travelers
(2016-09-26)Dengue virus sequences used in this study were obtained from two Iranian patients who were both with a history of traveling to Malaysia. The maximum likelihood phylogenetic tree demonstrated that two sequences were grouped ... -
Genetic and Clinical Characteristics of Patients in the Middle East With Multisystem Inflammatory Syndrome in Children
(2022)Importance: Clinical, genetic, and laboratory characteristics of Middle Eastern patients with multisystem in‐ flammatory syndrome in children (MIS-C) have not yet been documented. Objective: To assess the genetic and ... -
Genetic association of rs564398 polymorphism of the ANRIL long non-coding RNA gene and risk of type 2 diabetes: A meta-analysis
(2022)Abstract: Antisense non-coding RNA at the INK4 locus (ANRIL) is a long non-coding transcript localized within, and antisense to, the genes encoding the cyclin-dependent kinase inhibitor-2A/B (CDKN2A/B) on chromosome 9p21. ... -
Genetic contributions to autism spectrum disorder
(2021)Abstract: Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental conditions characterized by early childhood-onset impairments in communication and social interaction alongside restricted and ... -
Genetic determinants of severe COVID 19 in young Asian and Middle Eastern patients: a case series
(2023)Abstract: Studies of genetic factors associated with severe COVID-19 in young adults have been limited in non-Caucasian populations. Here, we clinically characterize a case series of patients with COVID19, who were otherwise ... -
Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing
(2021)Abstract: Breast fibroepithelial lesions are biphasic tumors which comprise the common benign fibroadenomas (FAs) and the rarer phyllodes tumors (PTs). This study analyzed 262 (42%) conventional FAs, 45 (7%) cellular FAs, ... -
Genetic loci associated with heart rate variabilityand their effects on cardiac disease risk
(2017)Abstract: Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for ... -
Genetic Variants and Protective Immunity against SARS-CoV-2
(2022-11)Abstract: The novel coronavirus-19 (SARS-CoV-2), has infected numerous individuals worldwide, resulting in millions of fatalities. The pandemic spread with high mortality rates in multiple waves, leaving others with ... -
Genetic Variants of the PLCXD3 Gene Are Associated with Risk of Metabolic Syndrome in the Emirati Population
(2020)Abstract: Phosphatidylinositol-specific phospholipase C X domain 3 (PLCXD3) has been shown to influence pancreatic _-cell function by disrupting insulin signaling. Herein, we investigated two genetic variants in the ... -
Genetic variation in the Middle East—an opportunity to advance the human genetics field
(2020)Abstract: We highlight the current lack of representation of the Middle East from large genomic studies and emphasize the expected high impact of cataloging its variation. We discuss the limiting factors and possible ... -
Genipin attenuates cisplatin-induced nephrotoxicity by counteracting oxidative stress, inflammation, and apoptosis
(2017-07-05)Abstract: Cisplatin (CP) is a potent and widely used chemotherapeutic agent. However, the clinical benefits of CP are compromised because it elicits nephrotoxicity and ototoxicity. In this study, we investigated the ... -
Genomic Context Analysis of de Novo STXBP1 Mutations Identifies Evidence of Splice Site DNA-Motif Associated Hotspots
(2018-02-22)Abstract: Mutations withinSTXBP1have been associated with a range of neuro developmental disorder simplicating the pleotropic impact of this gene. Although the frequency of de novo mutations withinSTXBP1for selective ... -
The Genomic Landscape of Pediatric Rheumatology Disorders in the Middle East
(2020)Abstract: Genetic investigations for patients with pediatric rheumatological disorders have been limited to classic genotyping testing, mainly MEFV hotspot mutation analysis, for periodic fever. Therefore, the landscape ... -
The genomic landscape of rare disorders in the Middle East
(2023)Background: Rare diseases collectively impose a significant burden on healthcare systems, especially in underserved regions, like the Middle East, which lack access to genomic diagnostic services and the associated ...