Browsing by Title
Now showing items 150-169 of 1365
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CART Cell Toxicities: New Insight into Mechanisms and Management
(2020)Abstract: T cells genetically engineered with chimeric antigen receptors (CART) have become a potent class of cancer immunotherapeutics. Numerous clinical trials of CART cells have revealed remarkable remission rates in ... -
A Case of COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome in Shock Managed by Cytokine Filtration
(2022)Abstract: Multisystem inflammatory syndrome in children (MIS-C) after COVID-19 has been recognized as a complication arising due to cytokine storm. Several management strategies including intravenous immunoglobulin and ... -
Case Report: A Case of Leukocyte Adhesion Deficiency, Type III Presenting With Impaired Platelet Function, Lymphocytosis and Granulocytosis
(2021)Abstract: Fermitin family homolog 3 (FERMT3), alternatively kindlin-3 (KIND3), is an integrin binding protein (of 667 residues) encoded by the FERMT3 gene. The molecule is essential for activating integrin aIIbb3 (the ... -
Case Report: BCG-Triggered Hemophagocytic Lymphohistiocytosis in an Infant With X-Linked Recessive Mendelian Susceptibility to Mycobacterial Disease Due to a Variant of Chronic Granulomatous Disease
(2021)Abstract: In the United Arab Emirates, BCG (Bacillus Calmette-Guérin) is administered to all newborns. We present here a young infant with an inborn error of immunity (IEI) who developed fatal adverse events to this ... -
Case Report: CMV-Associated Congenital Nephrotic Syndrome
(2020)Background: Congenital nephrotic syndrome, historically defined by the onset of large proteinuria during the first 3 months of life, is a rare clinical disorder, generally with poor outcome. It is caused by pathogenic ... -
Case Report: Expanding the Phenotypic Spectrum of Timothy Syndrome Type 1: A Sporadic Case With a de novo CACNA1C Pathogenic Variant and Segmental Ileal Dilatation
(2021)Background: Long QT syndactyly syndrome (long QT syndrome type 8), also known as Timothy Syndrome (TS) was first described in 1994 with still <50 case reported in the literature. The full spectrum of the syndrome is not ... -
Case Report: Guillain-Barré Syndrome as Primary Presentation of Systemic Lupus Erythematosus (SLE-GBS) in a Teenage Girl
(2022)Abstract: Peripheral nervous system involvement accounts for fewer than 10% of SLE cases with neuropsychiatric manifestations. Guillain-Barré syndrome (GBS) as the presenting, major manifestation of pediatric SLE is ... -
Case Report: Reactive Lymphohistiocytic Proliferation in Infant With a Novel Nonsense Variant of IL2RG Who Received BCG Vaccine
(2021)Abstract: We present here a male young infant with X-linked severe combined immunodeficiency (MIM#300400) due to the novel nonsense variant of IL2RG (interleukin 2 receptor, gamma; MIM#308380), NM_000206.2(IL2RG):c.820_823dup ... -
A case study evaluating the effect of clustering, publication bias, and heterogeneity on the meta analysis estimates in implant dentistry
(2023)Abstract: Meta-analyses may provide imprecise estimates when important meta-analysis parameters are not considered during the synthesis. The aim of this case study was to highlight the influence of meta-analysis parameters ... -
The catalytic role of Mystery Patient tools in shaping patient experience: A method to facilitate value co-creation using action research
(2018-10-12)Abstract: Improving patients’ experience in hospitals necessitates the improvement of service quality. Using mystery patients as a tool for assessing and improving patients’ experience is praised for its comprehensiveness. ... -
Cell free ACE2 RNA: A potential biomarker of COVID-19 severity
(2023)Abstract: Despite the downward trend of COVID-19 pandemic and increased immunity of the general population, COVID19 is still an elusive disease with risks due to emerging variants. Fast and reliable diagnosis of COVID-19 ... -
Cell‑specifc MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy
(2023)Abstract: Microtubule-associated protein tau (MAPT) aggregates in neurons, astrocytes and oligodendrocytes in a number of neurodegenerative diseases, including progressive supranuclear palsy (PSP). Tau is a target of ... -
Cementing the relationship between conventional and advanced semen parameters
(2021)Background: Afordable conventional semen analysis remains a fundamental procedure to be performed routinely during the diagnosis of male infertility. Advanced semen analyses provide valuable clinical insights in ... -
Challenges Associated with Effective Implementation of CT Dose Check Standards and Radiation Monitoring Index in Computed Tomography: Healthcare Sector Experience
(2022)Abstract: Computed tomography (CT) radiation dose management tools should be used whenever possible, particularly with the increasing demand for acquiring CT studies. Herein, we aim to assess the advantages and challenges ... -
Challenges faced by African healthcare workers during the third wave of the pandemic
(2022)Abstract: Africa experienced the third wave of the coronavirus disease in 2019, which caused an 18% rise in cases in most parts of the continent. As of January 2022, the region had an estimated 10.4 million cumulative ... -
Challenges of Establishing a de novo Consultation-Liaison Psychiatry Service in a Tertiary Hospital : Practical considerations and challenges
(2020)Abstract: Consultation-liaison psychiatry (CLP), also known as psychosomatic medicine, is a subspecialty of psychiatry that focuses on the care of patients with mental health disorders and general medical/surgical conditions. ... -
Challenging the Illusion: Health Equity Amidst New Variants
(2022)HIGHLIGHTS • LMICs with limited capacities and infrastructures have experienced striking and disproportionate public health and economic losses during the COVID-19 pandemic—particularly due to imposed lockdowns and ... -
Change management in higher education: A sequential mixed methods study exploring employees perception
(2023)Background: Higher education institutions need to put change management as a pivotal part of their strategy. The challenge is to effectively contextualize existing change management models to the respective work environment. ... -
Change management in higher education: A sequential mixed methods study exploring employees’ perception
(2023)Abstract: Background: Higher education institutions need to put change management as a pivotal part of their strategy. The challenge is to effectively contextualize existing change management models to the respective ... -
Changes In Children’s Oral-Health-Related Quality Of Life Following Dental Rehabilitation Under General Anesthesia In The United Arab Emirates
(2019)Background: Early Childhood Caries (ECC) is one of the most common childhood diseases in preschool children. Many young pediatric patients with ECC receive Dental treatment under Dental General Anesthesia (DGA). Changes ...