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Now showing items 310-329 of 1384
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Dephosphorylation of the Proneural Transcription Factor ASCL1 Re-Engages a Latent Post-Mitotic Differentiation Program in Neuroblastoma
(2020)Abstract: Pediatric cancers often resemble trapped developmental intermediate states that fail to engage the normal differentiation program, typified by high-risk neuroblastoma arising from the developing sympathetic ... -
Derangement of cell cycle markers in peripheral blood mononuclear cells of asthmatic patients as a reliable biomarker for asthma control
(2021)Abstract: In asthma, most of the identifed biomarkers pertain to the Th2 phenotype and no known biomarkers have been verifed for severe asthmatics. Therefore, identifying biomarkers using the integrative phenotype-genotype ... -
Derivation and characterization of putative craniofacial mesenchymal progenitor cells from human induced pluripotent stem cells
(2018)Abstract: The introduction and widespread adoption of induced pluripotent stem cell (iPSC) technology has opened new avenues for craniofacial regenerative medicine. Neural crest cells (NCCs) are the precursor population ... -
Descriptive histomorphological evaluation of the testis and caudal epididymis following treatment with rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) and sutherlandia (Lessertia frutescens) in healthy and streptozotocininduced diabetic rats
(2021)Objective: To evaluate the testis and the cauda epididymis after treating both healthy and diabetic rats with rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia), and sutherlandia (Lessertia frutescens), ... -
Descriptive Usability Study of CirrODS:Clinical Decision andWorkflow Support Tool for Management of Patients With Cirrhosis
(2019-07-03)Background: There are gaps in delivering evidence-based care for patients with chronic liver disease and cirrhosis. Objective: Our objective was to use interactive user-centered design methods to develop the Cirrhosis ... -
Design, Implementation and Evaluation of a Distance Learning Framework to Expedite Medical Education during COVID-19 pandemic: A Proof-of-Concept Study
(2021)Background: The COVID-19 pandemic has forced medical schools to suspend on-campus live-sessions and shift to distance-learning (DL). This precipitous shift presented medical educators with a challenge, ‘to create a ... -
Design, Implementation, and Evaluation of a Distance Learning Framework to Adapt to the Changing Landscape of Anatomy Instruction in Medical Education During COVID-19 Pandemic: A Proof-of-Concept Study
(2021)Abstract: This study presents the design of a DL-framework to deliver anatomy teaching that provides a microfiche of the onsite anatomy learning experience during the mandated COVID-19 lockdown. First, using nominal-group ... -
Design4Health Bootcamp: A design thinking approach to improve the 21st century skills of health, engineering and design students
(2020)Abstract— Global industries are acknowledging that professions as we know them will not require the same skills as they did in the 20th Century. Therefore how can universities prepare students for challenges that have not ... -
Detection of Clostridium difficile antigen and toxin in stool specimens: Comparison of the C. difficile quik chek complete enzyme immunoassay and GeneXpert C. difficile polymerase chain reaction assay
(2017)Background/Aims: Accurate and rapid laboratory diagnosis of Clostridium difficile infections (CDI) remains a significant challenge. A two‑step algorithm for detection of toxigenic C. difficile in stool based on initial ... -
Detection of copy number variants and genes by chromosomal microarray in an Emirati neurodevelopmental disorders cohort
(2022)Abstract: Copy number variations (CNVs) are highly implicated in the etiology of neurodevelopmental disorders (NDDs), and chromosomal microarray analysis (CMA) has been recommended as a frst-tier test for many NDDs. We ... -
Detection of OXA-23, GES-11 and NDM-1 among carbapenem-resistant Acinetobacter baumannii in Dubai: A preliminary study
(2021)Letter to Editor: Acinetobacter baumannii is a Gram-negative organism that has become a significant offender in health-care facilities, with the worldwide spread of carbapenem-resistant Acinetobacter baumannii (CRAB) ... -
Development and Comparison of Conventional and 3D-Printed Laboratory Models of Maxillary Defects
(2023)Background: Recording accurate impressions from maxillary defects is a critical and challenging stage in the prosthetic rehabilitation of patients following maxillectomy surgery. The aim of this study was to develop and ... -
Development of a calculated panel reactive antibody calculator for the United Arab Emirates: a proof of concept study
(2023)Abstract: Calculated panel reactive antibody (CPRA) is used to help increase sensitized patient’s access to transplantation. United Arab Emirates (UAE) has a diverse resident population hence we developed a UAE–CPRA ... -
Development of a dental reference data set for Emirati children and adolescents based on the Demirjian’s method
(2021)Background: The ability to predict the difference between chronological age (CA) and dental age (DA) is an important aid in the accurate diagnosis and treatment planning process in the pediatric population. Aim: To ... -
Development of a national Department of Veterans Affairs mortality risk prediction model among patients with cirrhosis
(2019)Objective: Cirrhotic patients are at high hospitalization risk with subsequent high mortality. Current risk prediction models have varied performances with methodological room for improvement. We used current analytical ... -
Development of a Radiographic Index for Periodontitis
(2021)Abstract: The use of radiographic indices is noticeably diminished due to the lack of simplicity and standardisation among the existing ones. The aim of this study was to introduce a radiographic index to aid clinicians ... -
Diabetes and carotid artery disease: a narrative review
(2020)Abstract: Diabetes mellitus (DM) has been linked to an increased prevalence and severity of carotid artery disease, as well as polyvascular disease. Carotid disease is also associated with obesity and abnormal peri-organ ... -
Diabetes and the COVID-19 Pandemic: How Insights from Recent Experience Might Guide Future Management
(2020)Summary: In summary, the COVID-19 pandemic is a huge challenge for diabetic patients and diabetologists, but it can be also an opportunity to improve physician–patient communication for better management of the disease ... -
Diabetes mellitus as a comorbidity in COVID-19 infection in the United Arab Emirates
(2021)Objectives: To compare risk factors and clinical outcomes among COVID-19 patients with or without diabetes in the United Arab Emirates (UAE). Methods: Data of 350 COVID-19 positive patients, admitted to Al Kuwait ... -
Diagnosing Cornelia de Lange syndrome and related neurodevelopmental disorders using RNA sequencing
(2020)Purpose: Neurodevelopmental disorders represent a frequent indication for clinical exome sequencing. Fifty percent of cases, however, remain undiagnosed even upon exome reanalysis. Here we show RNA sequencing (RNA-seq) ...