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Now showing items 11-20 of 48
Cardiovascular medications and regulation of COVID-19 receptors expression
(2020)
Introduction:
Emerging epidemiological studies suggested that Renin–Angiotensin–Aldosterone system (RAAS) inhibitors may increase infectivity and severity of COVID-19 by modulating the expression of ACE2.
Methods: ...
Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19
(2020)
Abstract:
The ongoing COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Age, smoking, obesity, and chronic diseases such as cardiovascular disease and diabetes have been described as risk factors for severe ...
Multiple early introductions of SARS‑CoV‑2 into a global travel hub in the Middle East
(2020)
Abstract:
International travel played a significant role in the early global spread of SARS-CoV-2. Understanding transmission patterns from different regions of the world will further inform global dynamics of the pandemic. ...
SARS-COV-2 (Covid-19) and male fertility: Where are we?
(2020)
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS COV-2), a single-stranded RNA virus, was found to be the causal agent of the disease called coronavirus disease. During December 2019, China informed the ...
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
(2020)
Introduction:
Clinical outcomes of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (COVID-19). Epidemiological studies have ...
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
(2020)
Introduction:
Three risk factors for life-threatening coronavirus disease 2019 (COVID-19) pneumonia have been identified— being male, being elderly, or having other medical conditions—but these risk factors cannot explain ...
Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection
(2020)
Abstract:
The immune system is tightly regulated by the activity of stimulatory and inhibitory immune receptors. This immune homeostasis is usually disturbed during chronic viral infection. Using publicly available ...
Implications of preexisting asthma on COVID-19 pathogenesis
(2021)
Abstract:
The coronavirus disease 2019 (COVID-19) pandemic spreading at an alarming rate has taken a heavy toll on the public healthcare systems and economies worldwide. An abnormal and overactivated inflammatory response ...
People’s Willingness to Vaccinate Against COVID-19 Despite Their Safety Concerns: Twitter Poll Analysis
(2021)
Background:
On January 30, 2020, the World Health Organization’s Emergency Committee declared the rapid, worldwide spread of COVID-19 a global health emergency. Since then, tireless efforts have been made to mitigate the ...
Twelve Months Down the Line: do we know Anything more about the Presence of the SARS-CoV-2 in Human Semen?
(2021)
Letter to Editor:
Based on current evidence, although the virus could be causing adverse effects in the male reproductive tract, its presence in Semen continues to be debated because current evidence suggests that the ...