Browsing Faculty Publications (CoM) by Title
Now showing items 1-20 of 924
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1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice
(2019)More than 90% of human pancreatic cancers carry the oncogenic mutant of Ki-RAS and their growth depends on its downstream kinase PAK1, mainly because PAK1 blocks the apoptosis of cancer cells selectively. We developed a ... -
A 12‑month prospective real‑life study of opicapone efficacy and tolerability in Emirati and non‑White subjects with Parkinson’s disease based in United Arab Emirates
(2023)Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and the condition is complicated by the emergence of wearing of/motor fuctuations with levodopa treatment after a variable period. ... -
2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2020)Abstract: In March 2020, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. At the genus rank, 20 new ... -
2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2021)Abstract: In March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by ... -
2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
(2022-11)Abstract: In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by ... -
The ABC-Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study
(2024-02)Abstract: Background: The ABC-stroke score is a risk scheme for prediction of stroke or systemic embolism (SE) in atrial fibrillation (AF). This study sought to examine whether the score could be useful in predicting ... -
ACE2 polymorphisms impact COVID-19 severity in obese patients
(2022-12)Abstract: A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. ... -
Action of 1,25(OH)2D3 on Human Asthmatic Bronchial Fibroblasts: Implications for Airway Remodeling in Asthma
(2020)Background: Airway fibroblasts are major contributors to the histopathological feature of airway remodeling in asthma by their implication in the cell invasiveness and profibrogenic secretory phenotype observed in ... -
Activity-Dependent Non-Coding RNA MAPK Interactome of the Human Epileptic Brain
(2023)Abstract: The human brain has evolved to have extraordinary capabilities, enabling complex behaviors. The uniqueness of the human brain is increasingly posited to be due in part to the functions of primate-specific, ... -
Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients
(2020)Abstract: Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population. Methods: A retrospective study ... -
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries
(2018)Background: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic ... -
Adolescent-Acquired Flatfeet: The Tip of the Iceberg
(2022-11)Abstract: There has been a substantive change in our lifestyle over the last two decades. The widespread availability of entertaining digital devices created an unhealthy culture of a sedentary lifestyle, with our children ... -
Adoption of the ADA/EASD guidelines in 10 Eastern and Southern European countries: Physician survey and good clinical practice recommendations from an international expert panel
(2020)Abstract: The aim of the present study was to assess the adoption of the ADA/EASD guidelines in a convenience sample of physicians from Eastern and Southern Europe, the barriers to the implementation of these guidelines ... -
Afghanistan's humanitarian crisis and its impacts on the mental health of healthcare workers during COVID-19
(2022-12)Abstract: Afghanistan’s humanitarian crisis has severely impacted the mental health of frontline workers. With the introduction of the Taliban government, ongoing civil unrest, and other forms of violent attacks, healthcare ... -
AFM-compatible microfluidic platform for affinity-based capture and nanomechanical characterization of circulating tumor cells
(2020)Abstract: Circulating tumor cells (CTCs) carried by the patient’s bloodstream are known to lead to the metastatic spread of cancer. It is becoming increasingly clear that an understanding of the nanomechanical characteristics ... -
African Swine Fever, the forgotten pandemic
(2021)Summary: African Swine Fever (ASF) is one of the most important diseases prevalent in swine populations. In recent times, it has devasted the pork industry—both commercial and backyard—throughout much of the world. ASF ... -
Age-related alterations and senescence of mesenchymal stromal cells: Implications for regenerative treatments of bones and joints
(2021)Abstract: The most common clinical manifestations of age-related musculoskeletal degeneration are osteoarthritis and osteoporosis, and these represent an enormous burden on modern society. Mesenchymal stromal cells (MSCs) ... -
AI-enhanced solutions during COVID-19: Current trends and future innovations
(2022-08)Abstract: Artificial Intelligence (AI) is defined as a branch of Computer Science that is capable of simulating intelligent behavior through machine automation systems. There has been a significant rise in research and ... -
Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD
(2020)Abstract: It has been reported that angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) are the main cell entry proteins for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ... -
Analgesia and sedation modalities used with botulinum toxin injections in children with cerebral palsy: a literature review
(2021)Abstract: Cerebral palsy (CP) is a non-progressive motor dysfunction leading to multiple morbidities, including spasticity, which can be managed with botulinum toxin injection (BTI). This literature review aims to examine ...