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Muscle sympathetic nerve activity-coupled changes in brain activity during sustained muscle pain
(2018-02-07)
Introduction:
Long-lasting experimental muscle pain elicits divergent muscle sympathetic responses, with some individuals exhibiting a persistent increase in muscle sympathetic nerve activity (MSNA), and others a decrease. ...
Work hour constraints in the German nursing workforce: A quarter of a century in review
(2018-07-18)
Background:
Work hour constraints (WHC), or the mismatch between desired and actual worktime, can negatively affect work productivity, job satisfaction, worker health and job fluctuations.
Objectives:
This study ...
Blending Gagne’s Instructional Model with Peyton’s Approach to Design an Introductory Bioinformatics Lesson Plan for Medical Students: Proof-of-Concept Study
(2018)
Background:
With the rapid integration of genetics into medicine, it has become evident that practicing physicians as well as medical students and clinical researchers need to be updated on the fundamentals of bioinformatics. ...
Genotyping of Staphylococcus aureus associated with nasal colonization among healthcare workers using DNA microarray
(2018-05)
Introduction:
Healthcare workers (HCWs) colonized with Staphylococcus aureus may serve as a reservoir of infection. This study was carried to determine the genetic make-up of S. aureusnasal colonizers in HCWs.
Method ...
Identification of early indicators of altered metabolism in normal development using a rodent model system
(2018-03-01)
Abstract:
Although the existence of a close relationship between the early maternal developmental environment, fetal size at birth and the risk of developing disease in adulthood has been suggested, most studies,however, ...
Taxonomy of the order Mononegavirales: update 2018
(2018-04-11)
Abstract:
In 2018, the order Mononegavirales was expanded by inclusion of 1 new genus and 12 novel species. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International ...
Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study
(2018-07)
Introduction:
Individual differences in heart rate variability (HRV) can be partly attributed to genetic factors that may be more pronounced during stress. Using data from the Oman Family Study (OFS), we aimed to estimate ...
The metaboreflex does not contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans
(2018-01-08)
Abstract:
Both central command and metaboreflex inputs from contracting muscles increase muscle sympathetic nerve activity (MSNA) to non-contracting muscle during sustainedisometric exercise. We recently showed that MSNA ...
Genomic Context Analysis of de Novo STXBP1 Mutations Identifies Evidence of Splice Site DNA-Motif Associated Hotspots
(2018-02-22)
Abstract:
Mutations withinSTXBP1have been associated with a range of neuro developmental disorder simplicating the pleotropic impact of this gene. Although the frequency of de novo mutations withinSTXBP1for selective ...
An ANKRD26 nonsense somatic mutation in a female with epidermodysplasia verruciformis (Tree Man Syndrome)
(2018-04-26)
Abstract:
Epidermodysplasia verruciformis (EV) is an extremely rare hereditary skin disease characterized by an abnormal susceptibility to the human papilloma virus (HPV) with an increased risk of cutaneous malignancy. ...