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Now showing items 11-20 of 29
The role of GLP-1 receptor agonists during COVID-19 pandemia: a hypothetical molecular mechanism
(2021)
Introduction:
A number of anti-diabetic treatments have been favored during the continuing spread of the current SARS-CoV-2 pandemic. Glucagon like peptide-1 receptor agonists (GLP1-RAs) are a group of antidiabetic drugs, ...
A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
(2017)
To the Editor:
The study by Fitzgerald et al. poses the question as to whether inclisiran is suitable for long-term treatment of hyperlipidemia. In contrast with PCSK9 antibodies, which target plasma PCSK9, inclisiran ...
Counterfeit and substandard drugs in Sub-Saharan Africa may pose a major hurdle to H3Africa’s initiative to study genetics of kidney disease progression
(2017)
To the Editor:
The Human Heredity and Health in Africa Kidney Disease Research Network aims to investigate the genetics of renal disease progression.1 Diabetes mellitus and hypertension have emerged as the commonest ...
Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence
(2022)
Abstract:
Periodontitis is a microbially driven, host-mediated disease that leads to loss of periodontal attachment and resorption of bone. It is associated with the elevation of systemic inflammatory markers and with the ...
Telemedicine for diabetes management during COVID-19: what we have learnt, what and how to implement
(2023)
Abstract:
The past two decades have witnessed telemedicine becoming a crucial part of health care as a method to facilitate doctor-patient interaction. Due to technological developments and the incremental acquisition of ...
Students’ Perception of Formative Assessment as an Instructional Tool in Competency-Based Medical Education: Proposal for a Proof-of-Concept Study
(2023)
Background:
In competency-based medical education (CBME), “Assessment for learning” or “Formative Assessment” (FA) plays a key role in augmenting student learning. FAs help students to measure their progress over time, ...
Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health
(2022)
Abstract:
Obesity, type 2 diabetes (T2DM), hypertension (HTN), and Cardiovascular Disease (CVD) often cluster together as “Cardiometabolic Disease” (CMD). Just under 50% of patients with CMD increased the risk of morbidity ...
Post-COVID syndrome, inflammation, and diabetes
(2022)
Abstract:
The raging COVID-19 pandemic is in its third year of global impact. The SARS CoV 2 virus has a high rate of spread, protean manifestations, and a high morbidity and mortality in individuals with predisposing ...
The Relationship between COVID-19 and Hypothalamic–Pituitary–Adrenal Axis: A Large Spectrum from Glucocorticoid Insufficiency to Excess—The CAPISCO International Expert Panel
(2022)
Abstract:
Coronavirus disease 2019 (COVID-19) is a highly heterogeneous disease regarding severity, vulnerability to infection due to comorbidities, and treatment approaches. The hypothalamic– pituitary–adrenal (HPA) ...
Reconnoitering the Therapeutic Role of Curcumin in Disease Prevention and Treatment: Lessons Learnt and Future Directions
(2022)
Abstract:
Turmeric is a plant with a very long history of medicinal use across different cultures. Curcumin is the active part of turmeric, which has exhibited various beneficial physiological and pharmacological effects. ...