Counterfeit and substandard drugs in Sub-Saharan Africa may pose a major hurdle to H3Africa’s initiative ‎to study genetics of kidney disease progression

Abstract

To the Editor:‎ The Human Heredity and Health in Africa Kidney Disease Research Network aims to investigate the ‎genetics of renal disease progression.1 Diabetes mellitus and hypertension have emerged as the ‎commonest cause of endstage renal disease in Sub-Saharan Africa.2 Additionally, obstructive uropathy ‎‎(observed in malaria), HIV infection, and toxic nephropathies also contribute considerably. Therefore, ‎apposite management of the above conditions is essential before mapping the phenotype of renal-‎disease progression to the genotype. (Continued...)‎