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Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease
(2021)
Abstract:
The geographic location and heterogeneous multi-ethnic population of Dubai (United Arab Emirates; UAE) provide a unique setting to explore the global molecular epidemiology of SARS-CoV-2 and relationship between ...
COVID-19 and the Heart: A Systematic Review of Cardiac Autopsies
(2021)
Importance:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated cardiac injury has been postulated secondary to several mechanisms. While tissue diagnosis is limited during the acute illness, postmortem ...
Higher Temperatures, Higher Solar Radiation, and Less Humidity Is Associated With Poor Clinical and Laboratory Outcomes in COVID-19 Patients
(2021)
Background:
The COVID-19 pandemic varies between countries, with suggestions that weather might contribute to the transmission mode, disease presentation, severity, and clinical outcomes. Yet the exact link between climate ...
miRCOVID-19: Potential Targets of Human miRNAs in SARS-CoV-2 for RNA-Based Drug Discovery
(2021)
Abstract:
Sense-antisense interactions of long and short RNAs in human cells are integral to posttranscriptional gene regulation, in particular that of mRNAs by microRNAs. Many viruses, including severe acute respiratory ...
Maintenance of neutralizing antibodies over ten months in convalescent SARS-CoV-2 afflicted patients
(2021)
Abstract
Knowledge of the level and duration of protective immunity against SARS-CoV-2 after primary infection is of crucial importance for preventive approaches. Currently, there is a lack of evidence on the persistence ...
Implications of preexisting asthma on COVID-19 pathogenesis
(2021)
Abstract:
The coronavirus disease 2019 (COVID-19) pandemic spreading at an alarming rate has taken a heavy toll on the public healthcare systems and economies worldwide. An abnormal and overactivated inflammatory response ...
People’s Willingness to Vaccinate Against COVID-19 Despite Their Safety Concerns: Twitter Poll Analysis
(2021)
Background:
On January 30, 2020, the World Health Organization’s Emergency Committee declared the rapid, worldwide spread of COVID-19 a global health emergency. Since then, tireless efforts have been made to mitigate the ...
Twelve Months Down the Line: do we know Anything more about the Presence of the SARS-CoV-2 in Human Semen?
(2021)
Letter to Editor:
Based on current evidence, although the virus could be causing adverse effects in the male reproductive tract, its presence in Semen continues to be debated because current evidence suggests that the ...
The role of GLP-1 receptor agonists during COVID-19 pandemia: a hypothetical molecular mechanism
(2021)
Introduction:
A number of anti-diabetic treatments have been favored during the continuing spread of the current SARS-CoV-2 pandemic. Glucagon like peptide-1 receptor agonists (GLP1-RAs) are a group of antidiabetic drugs, ...
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
(2021)
Abstract:
Multisystem inflammatory syndrome in children (MIS-C) emerged in April 2020 in communities with high COVID-19 rates. This new condition is heterogenous but resembles Kawasaki disease (KD), a well-known but poorly ...