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Genomic medicine in the Middle East
(2021)
Abstract:
We discuss the current state of genomic medicine in Arab countries of the Middle East, a region with outsized contribution to Mendelian genetics due to inbreeding yet has poor representation in global variome ...
Multiple early introductions of SARS‑CoV‑2 into a global travel hub in the Middle East
(2020)
Abstract:
International travel played a significant role in the early global spread of SARS-CoV-2. Understanding transmission patterns from different regions of the world will further inform global dynamics of the pandemic. ...
Genomic medicine in the Middle East
(2021)
Abstract:
We discuss the current state of genomic medicine in Arab countries of the Middle East, a region with outsized contribution to Mendelian genetics due to inbreeding yet has poor representation in global variome ...
Genetic and Clinical Characteristics of Patients in the Middle East With Multisystem Inflammatory Syndrome in Children
(2022)
Importance:
Clinical, genetic, and laboratory characteristics of Middle Eastern patients with multisystem in‐ flammatory syndrome in children (MIS-C) have not yet been documented.
Objective:
To assess the genetic and ...
Coronary artery disease prevalence and outcome in patients hospitalized with acute heart failure: an observational report from seven Middle Eastern countries
(2016)
Objectives:
The purpose of this study was to report prevalence, clinical characteristics, precipitating factors, management and outcome of patients with coronary artery disease (CAD) among patients hospitalized with heart ...
Cardiovascular risk factor burden in Africa and the Middle East across country income categories: a post hoc analysis of the cross-sectional Africa Middle East Cardiovascular Epidemiological (ACE) study
(2018-02-12)
Background:
A significant number of cardiovascular disease (CVD)-related deaths occur in developing countries. An increasing prevalence of CVD is associated with a change in the macro-economy of these countries. In this ...
Disparity in ST-segment Elevation Myocardial Infarction Practices and Outcomes in Arabian Gulf Countries (Gulf COAST Registry).
(2017)
Objectives: The objective of this study is to describe contemporary management and 1‑year outcomes of patients hospitalized with ST‑segment elevation myocardial infarction (STEMI) in Arabian Gulf countries.
Methods: ...
Non-withdrawal of beta blockers in acute decompensated chronic and de novo heart failure with reduced ejection fraction in a prospective multicentre study of patients with acute heart failure in the Middle East
(2017-05-17)
Objectives: Beta blockers reduce mortality in heart failure (HF). However, it is not clear whether they should be temporarily withdrawn during acute HF.
Design: Analysis of prospectively collected data.
Setting: The ...
Systolic Blood Pressure on Admissionand Mortality in Patients HospitalizedWith Acute Heart Failure: ObservationsFrom the Gulf Acute Heart Failure Registry
(2017)
Abstract: We investigated the role of systolic blood pressure (SBP) in relation to in-hospital and postdischarge mortality in patients admitted with acute heart failure (AHF). The SBP of 4848 patients aged 18 years admitted ...
Use of Real-World Evidence for Healthcare Decision Making in the Middle East: Practical Considerations and Future Directions.
(2019)
Introduction:
Real-world evidence (RWE) is increasingly being used in coverage, reimbursement and formulary decisions for medicines globally.
Areas covered:
The Middle East (ME) region is significantly behind in ...