Browsing Faculty Publications (CoM) by Title
Now showing items 535-554 of 859
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A novel 6D-approach to radically transform undergraduate medical education: preliminary reflections from MBRU
(2018-12)Background: Designers of undergraduate medical education (UME) need to address the exponentially expanding volume and variability of scientific knowledge, where by didactic teaching techniques need to be augmented by ... -
A novel HRM assay for the simultaneous detection and differentiation of eight poxviruses of medical and veterinary importance
(2017-02-20)Abstract: Poxviruses belonging to the Orthopoxvirus, Capripoxvirus and Parapoxvirus genera share common host species and create a challenge for diagnosis. Here, we developed a novel multiplex PCR method for the simultaneous ... -
Novel Markers in Pediatric Acute Lymphoid Leukemia: The Role of ADAM6 in B Cell Leukemia
(2021)Background: The extensive genetic heterogeneity found in the B cell precursor acute lymphoblastic leukemia (BCP-ALL) subtype of childhood ALL represents a potential repository of biomarkers. To explore this potential, ... -
Novel mutations in actionable breast cancer genes by targeted sequencing in an ethnically homogenous cohort
(2019)Background: Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway, and particularly important for early detection and cancer prevention. The purpose of this study was to ... -
Novel mutations in actionable breastcancer genes by targeted sequencing in anethnically homogenous cohort
(2019)Background:Genetic testing is becoming an essential tool for breast cancer (BC) diagnosis and treatment pathway,and particularly important for early detection and cancer prevention. The purpose of this study was to explore ... -
A novel reconstructive approach of the lumbar vertebral column from 2D MRI to 3D models
(2022-11)Introduction: Low back pain (LBP), arising from the lumbar vertebral column (LVC), is a global burden, ranking highest in terms of disability. In the United Arab Emirates (UAE), there is a high prevalence of LBP in the ... -
Obesity and female infertility
(2023)Abstract: Infertility is a significant global health issue, with a negative impact on people's wellbeing and human rights. Despite the longstanding association between obesity and infertility, there remains uncertainty, ... -
Obesity and nonalcoholic fatty liver disease in type 1 diabetes mellitus patients
(2022-11)Introduction: Assessed the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with type 1 diabetes mellitus (T1DM). They included 15 children with T1DM and obesity, 34 children with T1DM but no obesity and ... -
The "obesity paradox" in patients with atrial fibrillation: Insights from the Gulf SAFE registry
(2022-11)Abstract: Background: The prognostic impact of obesity on patients with atrial fibrillation (AF) remains under-evaluated and controversial. Methods: Patients with AF from the Gulf Survey of Atrial Fibrillation Events ... -
Obsessive-Compulsive Symptoms in an Adolescent with Intellectual Disability
(2022)Abstract: Individuals with intellectual disability (ID) experience various psychiatric comorbidities including anxiety, depression, and obsessive-compulsive disorder (OCD) in a rate that is equivalent or higher than ... -
Occupational Exposure to Solar Radiation and the Eye: A Call to Implement Health Surveillance of Outdoor Workers
(2023)Abstract: Globally, hundreds of millions of outdoor workers are exposed to solar radiation (SR) for most of their work. Such occupational exposure is known to induce various adverse health effects on the eyes, mainly ... -
Occupational Health of Frontline HealthcareWorkers in the United Arab Emirates during the COVID-19 Pandemic: A Snapshot of Summer 2020
(2021)Abstract: The study aim was to understand the availability of personal protective equipment (PPE) and the levels of anxiety, depression, and burnout of healthcare workers (HCWs) in the United Arab Emirates (UAE). This ... -
oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR‑Cas9 edited cerebral organoids
(2023)Abstract: Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged in the identification of critical cell types perturbed by genetic risk variants in common, ... -
Omics and Male Infertility: Highlighting the Application of Transcriptomic Data
(2022)Abstract: Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples. Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, ... -
One-year all-cause mortality risk among atrial fibrillation patients in Middle East with and without diabetes: The Gulf SAFE registry
(2020)Background: Atrial fibrillation (AF) poses a great risk of mortality, especially when associated with diabetes mellitus (DM). OBJECTIVES: We aimed to investigate the rate and risk factors for mortality among AF patients ... -
One-year risks of stroke and death in patients with atrial fibrillation from different clinical settings: The Gulf SAFE registry and Darlington AF registry
(2019)Background: AF patients from different clinical settings may have varying outcomes. We aimed to provide patient-level comparisons using two cohorts of patients with AF from different settings. Purpose: We aimed to ... -
Optimizing biologic therapy in inflammatory bowel disease: a Delphi consensus in the United Arab Emirates
(2021)Background: Inflammatory bowel diseases (IBD) are chronic, relapsing-remitting inflammatory conditions with a substantial negative impact on health-related quality of life and work productivity. Treatment of IBD has been ... -
Optimizing the management of HER2-negative metastatic breast cancer in the era of PARP inhibitors—proceedings from breast cancer expert group meeting
(2020)Abstract: The therapeutic landscape of human epidermal growth factor receptor 2-negative (HER2−) metastatic breast cancer (mBC) has evolved considerably with the introduction of newer targeted agents such as poly-ADP ... -
Oral cavity and oropharyngeal cancer incidence trends and disparities in the United States: 2000–2010
(2015-05-11)Background: Changes in the incidence of oral cancer based on anatomic location and demographic factors over time have been reported in the United States. The purpose of this study was to use recent data to examine oral ... -
OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
(2018-02-01)Abstract: Copy-number variations (CNVs) are strong risk factors for neurodevelopmental and psychiatric disorders. The 15q13.3 microdeletion syndrome region contains up to ten genes and is associated with numerous conditions, ...