MBRU Knowledge Repository: Recent submissions
Now showing items 241-260 of 1430
-
Potentially Zoonotic Viruses in Wild Rodents, United Arab Emirates, 2019—A Pilot Study
(2023)Abstract: The majority of emerging viral infectious diseases in humans originate from wildlife reservoirs, such as rodents and bats. We investigated a possible reservoir, namely wild gerbils and mice trapped in a desert ... -
Potentials of additional copper filtration on radiation dose and image quality for adults underwent digital chest X-ray imaging in Dubai Health Authority - UAE
(2023)Objective: To explore the potentials of adding copper (Cu) filter on image quality and patient dose of adult patients underwent chest X-ray examination Methods: Patients were divided into four groups. Group 1, ... -
Identification of Specific Biomarkers and Pathways in the Treatment Response of Infliximab for Inflammatory Bowel Disease: In-Silico Analysis
(2023)Background: Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract. In biological therapy, infliximab became the first anti-tumor necrosis factor (TNF) agent approved for ... -
An Unusual Presentation of Cardiofaciocutaneous Syndrome Diagnosed Through Whole Genome Sequencing: A Case Report
(2023)Abstract: Cardiofaciocutaneous syndrome is a rare, sporadic disease caused by germline mutations in the Ras/MAPK (mitogen-activated protein kinase) pathway. Patients usually present with craniofacial anomalies, cardiac ... -
Results from the United Arab Emirates 2022 report card on physical activity for children and adolescents
(2023)Background/Objective: The United Arab Emirates (UAE) 2022 Report Card provides a systematic evaluation of the physical activity (PA) levels of children and adolescents in the UAE. Methods: The 2022 Report Card ... -
Peptidomic analysis of the host-defense peptides in skin secretions of the Amazon River frog Lithobates palmipes (Ranidae)
(2023)Abstract: Skin secretions of certain frog species represent a source of host-defense peptides (HDPs) with therapeutic potential and their primary structures provide insight into taxonomic and phylogenetic relationships. ... -
Impact of #PsychTwitter in promoting global psychiatry: A hashtag analysis study
(2023)Introduction: Multiple studies have shown how valuable Twitter hashtags can be for promoting content related to dierent themes in the online community. This arena has grown into a rich data source for public health ... -
Vagus Nerve Stimulation and Its Cardioprotective Abilities: A Systematic Review
(2023)Abstract: Despite the vagus nerve stimulator (VNS) being used in neuroscience, it has recently been highlighted that it has cardioprotective functions. However, many studies related to VNS are not mechanistic in nature. ... -
A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons
(2023)Abstract: The SARS-CoV-2 delta variant (B.1.617.2) appeared for the first time in December 2020 and later spread worldwide. Currently available vaccines are not so efficacious in curbing the viral pathogenesis of the ... -
DKK3’s protective role in prostate cancer is partly due to the modulation of immune-related pathways
(2023)Introduction: While it is considered one of the most common cancers and the leading cause of death in men worldwide, prognostic stratification and treatment modalities are still limited for patients with prostate cancer ... -
Laparoscopic uretero-ileal substitution preserving the natural anti-reflux mechanism: A case report
(2023)Abstract: Ureteral strictures constitute one of the most common sequelae of impacted ureteral stones. Uretero-ileal substitution is an established treatment for long benign ureteral strictures, measuring more than 2 cm, ... -
Insights into Synonymous Codon Usage Bias in Hepatitis C Virus and Its Adaptation to Hosts
(2023)Abstract: Hepatitis C virus (HCV) is enveloped RNA virus, encoding for a polyprotein that is processed by cellular proteases. The virus is responsible for liver cirrhosis, allograft rejection, and human hepatocellular ... -
In Silico Analysis of Publicly Available Transcriptomic Data for the Identification of Triple-Negative Breast Cancer-Specific Biomarkers
(2023)Background: Breast cancer is the most common type of cancer among women and is classified into multiple subtypes. Triple-negative breast cancer (TNBC) is the most aggressive subtype, with high mortality rates and limited ... -
Association Between Self-Reported Polycystic Ovary Syndrome with Chronic Diseases Among Emiratis: A Cross-Sectional Analysis from the UAE Healthy Future Study
(2023)Purpose: This study aimed to assess the prevalence of self-reported polycystic ovary syndrome (PCOS) among Emiratis and examine bi-directional associations of PCOS with self-reported chronic diseases, namely: diabetes, ... -
Implications and theragnostic potentials of circular RNAs in rheumatic diseases
(2023)Abstract: Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has shown that aberrant expression of ... -
Pathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?
(2023)Introduction: A recent study investigating astronaut jugular venous flow inflight on the International Space Station (ISS) reported the incidental finding of a persistent asymptomatic obstructive left internal jugular ... -
Mystery of fatal ‘staggering disease’ unravelled: novel rustrela virus causes severe meningoencephalomyelitis in domestic cats
(2023)Introduction: ‘Staggering disease’ is a neurological disease entity considered a threat to European domestic cats (Felis catus) for almost five decades. However, its aetiology has remained obscure. Rustrela virus (RusV), ... -
Ankle dorsiflexion assist using a single sensor-based FES: Results from clinical study on patients with stroke
(2023)Objective: Ankle foot orthosis (AFO) commonly prescribed to manage foot-drop following stroke restricts ankle mobility. Commercially available functional electrical stimulation (FES) is an expensive alternative to achieve ... -
Twitter-based crowdsourcing: What kind of measures can help to end the COVID-19 pandemic faster?
(2022)Background: Crowdsourcing is a low-cost, adaptable, and innovative method to collect ideas from numerous contributors with diverse backgrounds. Crowdsourcing from social media like Twitter can be used for generating ideas ... -
Prevalence and Risk Factors of Refractive Errors and Effective Spectacle Coverage in Emiratis and Non-Emiratis Aged 40 Years or Older: the Dubai Eye Health Survey
(2023)Purpose: The aim was to investigate the prevalence and risk factors of refractive errors (REs) and the effective spectacle coverage in Emiratis and non-Emiratis in Dubai. Design: The Dubai Eye Health Survey was a ...