MBRU Knowledge Repository: Recent submissions
Now showing items 1-20 of 211
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A double-blind placebo-controlled clinical investigation into pain reduction effect of placing the pain spot outside the intersection area of the two currents of interferential therapy compared to traditional method
(2018-01-26)Background: Interferential therapy (IFT) is applied to intersect in the painful area but no confirmed effect with this method. Experimentally, the highest voltage of IFT is induced outside the intersection of the two ... -
Predictors of Shoulder Degeneration in the KwaZulu-Natal Population of South Africa
(2018-03)Abstract: The critical shoulder angle and acromion index are conventional radiological tools employed as predictors of shoulder degeneration. As they represent the static components of glenohumeral stability, the ... -
Muscle sympathetic nerve activity-coupled changes in brain activity during sustained muscle pain
(2018-02-07)Introduction: Long-lasting experimental muscle pain elicits divergent muscle sympathetic responses, with some individuals exhibiting a persistent increase in muscle sympathetic nerve activity (MSNA), and others a decrease. ... -
Spatial and Phylodynamic Survey on Crimean-Congo Hemorrhagic Fever Virus Strains in Northeast of Iran
(2018-01-29)Background: Crimean-Congo hemorrhagic fever (CCHF) is asymptomatic in infected animals, yet the virus poses a serious threat to humans causing a symptomatic, hemorrhagic disease with a high case-fatality rate. Numerous ... -
Factors Affecting Transmission of Crimean - Congo Hemorrhagic Fever among Slaughterhouse Employees: A Serosurvey in Mashhad, Iran
(2018-02-12)Background: Crimean - Congohemorrhagic fever (CCHF) is a severe viral disease. Slaughterhouses are potentially high risk working environments for CCHF infection due to close contact of livestock and humans. Objectives: The ... -
Nootkatone confers hepatoprotective and anti-fibrotic actions in amurine model of liver fibrosis by suppressing oxidative stress, inflammation, and apoptosis
(2017-11-20)Abstract: In this study, the hepatoprotective and anti-fibrotic actions of nootkatone (NTK) were investigated using carbon tetrachloride (CCl4)-induced liver fibrosis in mice. CCl4 administration elevated serum aspartate ... -
Founder mutation in IKBKAP gene causes vestibular impairment in familial dysautonomia
(2018)Objective: To assess vestibular function in patients with familial dysautonomia (FD), a hereditary sensory and autonomic neuropathy – caused by a mutation in the IKBKAP gene (c.2204 + 6 T > C) – and characterized by marked ... -
OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
(2018-02-01)Abstract: Copy-number variations (CNVs) are strong risk factors for neurodevelopmental and psychiatric disorders. The 15q13.3 microdeletion syndrome region contains up to ten genes and is associated with numerous conditions, ... -
Cardiovascular risk factor burden in Africa and the Middle East across country income categories: a post hoc analysis of the cross-sectional Africa Middle East Cardiovascular Epidemiological (ACE) study
(2018-02-12)Background: A significant number of cardiovascular disease (CVD)-related deaths occur in developing countries. An increasing prevalence of CVD is associated with a change in the macro-economy of these countries. In this ... -
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries
(2018)Background: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic ... -
Incidence and impact of cardiorenal anaemia syndrome on all-cause mortality in acute heart failure patients stratified by left ventricular ejection fraction in the Middle East
(2018-10-12)Aims: This study aims to evaluate the incidence and impact of cardiorenal anaemia syndrome (CRAS) on all-cause mortality in acute heart failure (AHF) patients stratified by left ventricular ejection fraction (LVEF) status ... -
Maternal and birth cohort studies in the Gulf Cooperation Council countries: protocol for a systematic review and narrative evaluation
(2018)Introduction: Cohort studies have revealed that genetic, socioeconomic, communicable and noncommunicable diseases, and environmental exposures during pregnancy may influence the mother and her pregnancy, birth delivery ... -
Association of IMMP2L deletions with autism spectrum disorder: A trio family study and meta-analysis
(2018)Abstract: IMMP2L, the gene encoding the inner mitochondrial membrane peptidase subunit 2- like protein, has been reported as a candidate gene for Tourette syndrome, autism spectrum disorder (ASD) and additional ... -
Clinical relevance of the arterial supply to the proximal rectum
(2018-01)Abstract: Although the rectum is considered to be an organ rich in vascularity, the exact role of the middle rectal artery appears to be an area of much debate. Despite its principal supply from the superior rectal artery, ... -
Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer
(2017-05-11)Abstract: Serum from one hundred and ten breast cancer patients and thirty healthy female volunteers, were prospectively collected and evaluated for serum levels of Shh and IL-6 using human Shh and IL-6 specific enzyme-linked ... -
Epithelial Mesenchymal Transition (EMT) in Metastatic Breast Cancer in Omani Women
(2017-05-19)Abstract: Breast cancer (BC) in Oman affects younger women and has a more aggressive course. Clinical and biological variables like age, pregnancy, tumor size, type, grade, receptor expression and proliferation predict ... -
Ileal Transposition in Rats Reduces Energy Intake, Body Weight, and Body Fat Most Efficaciously When Ingesting a High-Protein Diet
(2020)Purpose: Ileal transposition (IT) allows exploration of hindgut effects of bariatric procedures in inducing weight loss and reducing adiposity. Here we investigated the role of dietary macronutrient content on IT effects ... -
Global evidence on occupational sun exposure and keratinocyte cancers: a systematic review
(2020)Summary: Individual studies have suggested that the association between occupational exposure to solar ultraviolet radiation (UVR) and the development of keratinocyte cancers (KCs) may only be valid in populations of ... -
SARS-CoV-2 and the testis: similarity with other viruses and routes of infection
(2020)Abstract: Since the start of the latest coronavirus (SARS-CoV-2) outbreak, the number of infected individuals and cases of coronavirus disease (COVID-19) has been increasing exponentially worldwide. Of interest is existing ... -
Diabetes and the COVID-19 Pandemic: How Insights from Recent Experience Might Guide Future Management
(2020)Summary: In summary, the COVID-19 pandemic is a huge challenge for diabetic patients and diabetologists, but it can be also an opportunity to improve physician–patient communication for better management of the disease ...