MBRU Knowledge Repository: Recent submissions
Now showing items 21-40 of 1358
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Gender-specific Reference Range for Serum Leptin in Omani Population
(2023)Objectives: Leptin is a hormone that contributes to glucose homeostasis and food intake regulation via its action on the hypothalamus. Leptin level increases with obesity and overfeeding and decreases with energy deficiency. ... -
Long-Term Recurrent Intramedullary Arachnoid Cyst: Case Report and Literature Review
(2023)Objectives: This article reports the management of a case of a 32-year-old male who presented with progressive weakness in the lower limbs and spastic paraparesis secondary to an intramedullary arachnoid cyst (IMAC). For ... -
Perinatal Risk Factors in Children Diagnosed with Autism Spectrum Disorder in Dubai: A Case-Control Study
(2023)Introduction: Autism spectrum disorder (ASD) is a heterogeneous disorder characterized by deficits in socialemotional reciprocity and associated behavioral symptoms. The goal of this study was to examine perinatal risk ... -
Genetic determinants of severe COVID 19 in young Asian and Middle Eastern patients: a case series
(2023)Abstract: Studies of genetic factors associated with severe COVID-19 in young adults have been limited in non-Caucasian populations. Here, we clinically characterize a case series of patients with COVID19, who were otherwise ... -
Nigella sativa and its chemical constituents: pre clinical and clinical evidence for their potential anti SARS CoV 2 effects
(2023)Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 500 million reported cases of COVID-19 worldwide with relatively high morbidity and mortality. Although global vaccination drive has ... -
Retinal venular vessel diameters are smaller during ten days of bed rest
(2024)Introduction: Older individuals experience cardiovascular dysfunction during extended bedridden hospital or care home stays. Bed rest is also used as a model to simulate accelerated vascular deconditioning occurring during ... -
Inflammatory response to epoxy resin and calcium silicate sealers preheated with different temperatures: an in vivo study
(2023-02)Abstract Objective: To determine the impact of heat exposure of different sealers on inflammatory cytokine secretions and tissue response in vivo. Materials and methods: Silicone tubes were prefilled with epoxy resin ... -
Reduction in prevalence of spousal physical violence against women in India: evidence from three national surveys
(2023)Abstract: Spousal physical violence (PV) against women is considered to be major health issue in developing countries. Lifetime physical violence is a composite outcome consists of hit, kick, beat, slap and threatened ... -
The Use of Bone Density Scan in Monitoring Treatment Response in Patients Diagnosed with Osteoporosis: A Retrospective Cohort Study
(2023)Abstract: Osteoporosis is characterized as a metabolic bone disease defined by low bone mineral density (BMD) and bone tissue degeneration, particularly a reduction in the number of trabeculae and a drop in cortical bone ... -
Prevalence of Hepatocellular Carcinoma in Hepatitis B Population within Southeast Asia: A Systematic Review and Meta-Analysis of 39,050 Participants
(2023)Background and aim: Hepatocellular carcinoma (HCC) is a significant complication of hepatitis B and still poses a global public health concern. This systematic review and meta-analysis provide adequate details on the ... -
Exercise Therapy in the Management of Peripheral Arterial Disease
(2023)Abstract: The incidence and prevalence of peripheral artery disease (PAD) are increasing globally and have a marked economic burden in the United States. The American Heart Association/American College of Cardiology ... -
A rapid whole-genome sequencing service for infants with rare diseases in the United Arab Emirates
(2023)Introduction: A large body of evidence now supports use of rapid whole-genome sequencing (rWGS) as a cost-effective tool for timely diagnosis and tailored management of critically ill children with rare diseases. However, ... -
Spindle cell lipoma of the tongue: First case report from the Gulf region and review of the literature
(2023)Introduction: Lipomas are prevalent benign soft tissue neoplasms of mesenchymal origin that develop in up to 20% of cases in the head and neck area. Oral lipoma is considered to account for 1% to 4% of all benign mouth ... -
A Rare Case of Sarcoidosis Presenting as an Isolated Breast Mass and Pain: A Case Report and Literature Review
(2023)Abstract: Objective: Rare disease Background: Sarcoidosis is a benign systemic granulomatous disorder of unknown etiology that affects multiple organs. Patients diagnosed with sarcoidosis usually present with nonspecific ... -
Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease
(2023)Abstract: Congenital heart disease (CHD) is one of the most prevalent neonatal congenital anomalies. To catalog the putative candidate CHD risk genes, we collected 16,349 variants [single-nucleotide variants (SNVs) and ... -
A 12‑month prospective real‑life study of opicapone efficacy and tolerability in Emirati and non‑White subjects with Parkinson’s disease based in United Arab Emirates
(2023)Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and the condition is complicated by the emergence of wearing of/motor fuctuations with levodopa treatment after a variable period. ... -
Systemic Lupus Erythematosus Presenting With Severe Hypothyroidism and Extensive Pericardial Effusion in a Child
(2023)Abstract: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, which may be associated with other autoimmune diseases, like autoimmune hypothyroidism. Both disorders can involve the cardiovascular system ... -
Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021
(2023)Abstract: As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. ... -
Application of CRISPR-Cas System to Mitigate Superbug Infections
(2023)Abstract: Multidrug resistance in bacterial strains known as superbugs is estimated to cause fatal infections worldwide. Migration and urbanization have resulted in overcrowding and inadequate sanitation, contributing to ... -
Anti-Inflammatory Effects of Bioactive Compounds from Seaweeds, Bryozoans, Jellyfish, Shellfish and Peanut Worms
(2023)Abstract: Inflammation is a defense mechanism of the body in response to harmful stimuli such as pathogens, damaged cells, toxic compounds or radiation. However, chronic inflammation plays an important role in the ...