Search
Now showing items 21-30 of 93
SARS-COV-2 (Covid-19) and male fertility: Where are we?
(2020)
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS COV-2), a single-stranded RNA virus, was found to be the causal agent of the disease called coronavirus disease. During December 2019, China informed the ...
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
(2020)
Introduction:
Clinical outcomes of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (COVID-19). Epidemiological studies have ...
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
(2020)
Introduction:
Three risk factors for life-threatening coronavirus disease 2019 (COVID-19) pneumonia have been identified— being male, being elderly, or having other medical conditions—but these risk factors cannot explain ...
Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection
(2020)
Abstract:
The immune system is tightly regulated by the activity of stimulatory and inhibitory immune receptors. This immune homeostasis is usually disturbed during chronic viral infection. Using publicly available ...
Combination of obesity and co-morbidities leads to unfavorable outcomes in COVID-19 patients
(2020)
Objective:
Obesity has been described as a significant independent risk factors of COVID-19. We aimed to study the association between obesity, co-morbidities and clinical outcomes of COVID-19.
Methods:
Clinical ...
Medical and Health-Related Misinformation on Social Media: Bibliometric Study of the Scientific Literature
(2022)
Background:
Social media has been extensively used for the communication of health-related information and consecutively for the potential spread of medical misinformation. Conventional systematic reviews have been published ...
Host transcriptomic profiling of COVID-19 patients with mild, moderate, and severe clinical outcomes
(2021)
Abstract:
Characterizing key molecular and cellular pathways involved in COVID-19 is essential for disease prognosis and management. We perform shotgun transcriptome sequencing of human RNA obtained from nasopharyngeal ...
Implications of preexisting asthma on COVID-19 pathogenesis
(2021)
Abstract:
The coronavirus disease 2019 (COVID-19) pandemic spreading at an alarming rate has taken a heavy toll on the public healthcare systems and economies worldwide. An abnormal and overactivated inflammatory response ...
People’s Willingness to Vaccinate Against COVID-19 Despite Their Safety Concerns: Twitter Poll Analysis
(2021)
Background:
On January 30, 2020, the World Health Organization’s Emergency Committee declared the rapid, worldwide spread of COVID-19 a global health emergency. Since then, tireless efforts have been made to mitigate the ...
Prediction of COVID-19 severity using laboratory findings on admission: informative values, thresholds, ML model performance
(2021)
Background:
Despite the necessity, there is no reliable biomarker to predict disease severity and prognosis of patients with COVID-19. The currently published prediction models are not fully applicable to clinical ...