MBRU Knowledge Repository: Recent submissions
Now showing items 861-880 of 1430
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Dorsal root ganglion stimulation: a new target for autonomic neuromodulation?
(2021)Abstract: Dysautonomias are typifed by aberrant output of either the sympathetic or parasympathetic nervous system resulting in an array of manifestations across multiple body systems. Neuromodulation of the autonomic ... -
Natural compound catechol induces DNA damage, apoptosis, and G1 cell cycle arrest in breast cancer cells
(2020)Abstract: Targeting cell cycle and inducing DNA damage by activating cell death pathways are considered as effective therapeutic strategy for combating breast cancer progression. Many of the naturally known small molecules ... -
Three-dimensional evaluation of scapular morphology in primary glenohumeral arthritis, rotator cuff arthropathy, and asymptomatic shoulders
(2021)Aim and background: Recently, the 3D morphology of the coracoacromial complex in non-pathologic shoulders have been described. The aim of this study was to evaluate and compare the coracoacromial complex in pathological ... -
Comprehensive Ocular Examination of Healthy Newborns in the Middle East
(2020)Purpose: To report the prevalence of the perinatal ocular disease in healthy infants referred to a referral eye centre in the Middle East region for comprehensive ocular examinations. Methods: All healthy full-term ... -
An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder
(2020)Abstract: This study explored the physical and clinical phenotype of Bangladeshi children with autism spectrum disorder (ASD). A totally of 283 children who were referred for screening and administered Module 1 of the ... -
Association of obesity indices with in-hospital and 1-year mortality following acute coronary syndrome
(2020)Background/objectives: According to the “obesity paradox”, adults with obesity have a survival advantage following acute coronary syndrome, compared with those without obesity. Previous studies focused on peripheral ... -
Does Hospital Teaching Status Affect the Outcomes of Patients Undergoing Anterior Cervical Discectomy and Fusion?
(2020)Background: Teaching hospitals are responsible for the training and education of residents and have been centers of research and advancement in an era of evidence-based medicine. Several studies have reported conflicting ... -
Molecular Characterization of Staphylococcus aureus Isolates Associated with Nasal Colonization and Environmental Contamination in Academic Dental Clinics
(2020)Aim: To determine the genetic makeup of methicillin-sensitive/methicillin-resistant Staphylococcus aureus (MSSA/MRSA) from nasal colonization and environmental contamination in dental clinics. Materials and Methods: ... -
Intermittent use of biologic agents for the treatment of psoriasis in adults
(2020)Abstract: Current clinical recommendations suggest that continuous treatment of moderate to severe psoriasis with biologic agents is more effective than intermittent treatment in terms of achieving remission and maintaining ... -
Implication of genetic variants in overweight and obesity susceptibility among the young Arab population of the United Arab Emirates
(2020)Objective: Overweight and obesity are major risk factors for Type 2 Diabetes Mellitus (T2DM), cardiovascular disease (CVD) and cancer. Genetic predisposition has been shown to play a key role in obesity, and genome-wide ... -
Dimensional analysis of the bicipital groove and its associated pathology in a South African population
(2020)Abstract: The bicipital groove (BG) forms an indentation between the greater and lesser humeral tubercles and lodges the long head of biceps brachii tendon (LHBBT) along with the ascending branch of the circumflex humeral ... -
Mechanisms of pain in sickle cell disease
(2020)Objectives: The hallmark of sickle cell disease (SCD) is acute and chronic pain, and the pain dominates the clinical characteristics of SCD patients. Although pharmacological treatments of SCD targeting the disease ... -
The efect of streptozotocin induced diabetes on sperm function: a closer look at AGEs, RAGEs, MAPKs and activation of the apoptotic pathway
(2020)Abstract: This study was designed to (1) investigate the possible mechanisms through which diabetes-induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) activation can afect male reproductive ... -
Evidence based treatment for developmental dysplasia of the hip in children under 6 months of age. Systematic review and exploratory analysis
(2020)Introduction: Developmental dysplasia of the hip (DDH) is a common paediatric orthopaedic condition that attracts a substantive amount of controversy. The treatments vary because of the wide spectrum of the condition and ... -
Non-coronary atherosclerotic cardiovascular disease in patients with familial hypercholesterolaemia
(2020)Objective: Familial hypercholesterolaemia (FH) is a common autosomal dominant inherited disease, affecting 1 in 200 - 500 individuals worldwide. FH is characterized by elevated circulating low-density lipoprotein cholesterol ... -
Ventricular Arrhythmias in Patients with Spontaneous Coronary Artery Dissection
(2020)Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome in young women, with a wide clinical spectrum of severity. Ventricular arrhythmia (VA) can occur ... -
One-year all-cause mortality risk among atrial fibrillation patients in Middle East with and without diabetes: The Gulf SAFE registry
(2020)Background: Atrial fibrillation (AF) poses a great risk of mortality, especially when associated with diabetes mellitus (DM). OBJECTIVES: We aimed to investigate the rate and risk factors for mortality among AF patients ... -
The Distribution of Colorectal Surgeons in the United States
(2020)Background: Surgical resection is a mainstay of colorectal cancer treatment, and prior studies have shown improved outcomes in patients undergoing surgery for colorectal cancer by colorectal surgical specialists compared ... -
Phytochemical drug candidates for the modulation of peroxisome proliferator-activated receptor γ in inflammatory bowel diseases
(2020)Abstract: Plant-based compounds or phytochemicals such as alkaloids, glycosides, flavonoids, volatile oils, tannins, resins, and polyphenols have been used extensively in traditional medicine for centuries and more ... -
Male infertility: A proximate look at the advanced glycation end products
(2020)Abstract: Advanced glycation end products (AGEs) are products of cascades of non-enzymatic glycosylation. They are formed over a period of hours to days, depending on the protein lifetime. AGEs acts by independently ...