MBRU Knowledge Repository: Recent submissions
Now showing items 101-120 of 1430
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The Use of Bone Density Scan in Monitoring Treatment Response in Patients Diagnosed with Osteoporosis: A Retrospective Cohort Study
(2023)Abstract: Osteoporosis is characterized as a metabolic bone disease defined by low bone mineral density (BMD) and bone tissue degeneration, particularly a reduction in the number of trabeculae and a drop in cortical bone ... -
Prevalence of Hepatocellular Carcinoma in Hepatitis B Population within Southeast Asia: A Systematic Review and Meta-Analysis of 39,050 Participants
(2023)Background and aim: Hepatocellular carcinoma (HCC) is a significant complication of hepatitis B and still poses a global public health concern. This systematic review and meta-analysis provide adequate details on the ... -
Exercise Therapy in the Management of Peripheral Arterial Disease
(2023)Abstract: The incidence and prevalence of peripheral artery disease (PAD) are increasing globally and have a marked economic burden in the United States. The American Heart Association/American College of Cardiology ... -
A rapid whole-genome sequencing service for infants with rare diseases in the United Arab Emirates
(2023)Introduction: A large body of evidence now supports use of rapid whole-genome sequencing (rWGS) as a cost-effective tool for timely diagnosis and tailored management of critically ill children with rare diseases. However, ... -
Spindle cell lipoma of the tongue: First case report from the Gulf region and review of the literature
(2023)Introduction: Lipomas are prevalent benign soft tissue neoplasms of mesenchymal origin that develop in up to 20% of cases in the head and neck area. Oral lipoma is considered to account for 1% to 4% of all benign mouth ... -
A Rare Case of Sarcoidosis Presenting as an Isolated Breast Mass and Pain: A Case Report and Literature Review
(2023)Abstract: Objective: Rare disease Background: Sarcoidosis is a benign systemic granulomatous disorder of unknown etiology that affects multiple organs. Patients diagnosed with sarcoidosis usually present with nonspecific ... -
Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease
(2023)Abstract: Congenital heart disease (CHD) is one of the most prevalent neonatal congenital anomalies. To catalog the putative candidate CHD risk genes, we collected 16,349 variants [single-nucleotide variants (SNVs) and ... -
A 12‑month prospective real‑life study of opicapone efficacy and tolerability in Emirati and non‑White subjects with Parkinson’s disease based in United Arab Emirates
(2023)Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and the condition is complicated by the emergence of wearing of/motor fuctuations with levodopa treatment after a variable period. ... -
Systemic Lupus Erythematosus Presenting With Severe Hypothyroidism and Extensive Pericardial Effusion in a Child
(2023)Abstract: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, which may be associated with other autoimmune diseases, like autoimmune hypothyroidism. Both disorders can involve the cardiovascular system ... -
Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021
(2023)Abstract: As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. ... -
Application of CRISPR-Cas System to Mitigate Superbug Infections
(2023)Abstract: Multidrug resistance in bacterial strains known as superbugs is estimated to cause fatal infections worldwide. Migration and urbanization have resulted in overcrowding and inadequate sanitation, contributing to ... -
Anti-Inflammatory Effects of Bioactive Compounds from Seaweeds, Bryozoans, Jellyfish, Shellfish and Peanut Worms
(2023)Abstract: Inflammation is a defense mechanism of the body in response to harmful stimuli such as pathogens, damaged cells, toxic compounds or radiation. However, chronic inflammation plays an important role in the ... -
Peri-implantitis Through the Looking Glass
(2023)Introduction: The states of health and disease are inseparable, as the existence of one relies on the presence of the other. The definitions of health and disease in medicine and dentistry have evolved over the years from ... -
Seasonal Prevalence of Respiratory Pathogens Among Children in the United Arab Emirates: A Multicenter Cross-Sectional Study in the PreCOVID-19 Era
(2023)Background: Viral respiratory infections in children pose a significant burden on healthcare facilities globally. In the United Arab Emirates (UAE) these account for 15% of all healthcare encounters among children. ... -
Effectiveness of collaborative tele-mental health care for children with attention deficit hyperactivity disorder in United Arab Emirates
(2023)Background: Attention deficit hyperactivity disorder is a common neurodevelopmental disorder. Accessing services for this disorder is a worldwide challenge and requires innovative interventions. Aims: We aimed to ... -
Assessment of the Performance of Obesity Measures in the Screening of Hypertension in a South African Adolescent Population
(2023)Abstract: Obesity is known to be one of the most significant risk factors for essential hypertension in childhood. However, whether obesity cut-offs may predict hypertension screening in adolescents remains controversial. ... -
Indirect Treatment Comparison of First-Line CDK4/6-Inhibitors in Post-Menopausal Patients with HR+/HER2− Metastatic Breast Cancer
(2023)Background: CDK4/6-inhibitors have demonstrated similar efficacy and are considered an effective first-line endocrine treatment of patients with hormone-receptor positive (HR+)/humanepidermal-growth-factor-receptor-2 ... -
Sex Variations in Retinal Microcirculation Response to Lower Body Negative Pressure
(2023)Introduction: Lower body negative pressure (LBNP) is routinely used to induce central hypovolemia. LBNP leads to a shift in blood to the lower extremities. While the effects of LBNP on physiological responses and large ... -
Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas
(2023)Abstract: Polycystic Ovary Syndrome (PCOS) is associated with a 3 to 4-fold increased risk of endometrial cancer (EC), but molecular mechanisms are unclear. Upregulation of the IGF1 gene in PCOS endometrium may increase ... -
Palbociclib releases the latent differentiation capacity of neuroblastoma cells
(2023)Abstract: Neuroblastoma is the most common extracranial solid tumor in infants, arising from developmentally stalled neural crest-derived cells. Driving tumor differentiation is a promising therapeutic approach for this ...