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Genetic and Clinical Characteristics of Patients in the Middle East With Multisystem Inflammatory Syndrome in Children
(2022)
Importance:
Clinical, genetic, and laboratory characteristics of Middle Eastern patients with multisystem in‐ flammatory syndrome in children (MIS-C) have not yet been documented.
Objective:
To assess the genetic and ...
The "obesity paradox" in patients with atrial fibrillation: Insights from the Gulf SAFE registry
(2022-11)
Abstract:
Background: The prognostic impact of obesity on patients with atrial fibrillation (AF) remains under-evaluated and controversial.
Methods:
Patients with AF from the Gulf Survey of Atrial Fibrillation Events ...
Rapid whole genome sequencing of critically ill pediatric patients from genetically underrepresented populations
(2022)
Abstract:
We describe a case series of fve infants (age range: 1–90 days; 4 females and 1 male) who presented to Al Jalila Chil dren’s intensive care units (ICU) with complex multisystem disorders. Patients were Emirati, ...
Outcomes of guideline-based medical therapy in patients with acute heart failure and reduced left ventricular ejection fraction Observations from the Gulf acute heart failure registry (Gulf CARE)
(2022)
Abstract:
This study aimed to report on the use, predictors and outcomes of guideline-based medical therapy (GBMT) in patients with acute heart failure (HF) with reduced ejection fraction of 40% (HFrEF), from seven countries ...
Patients’ and physicians’ gender and perspective on shared decision-making: A cross-sectional study from Dubai
(2022)
Background:
Delivering patient-centered care is a declared objective of many health delivery systems globally, especially in an era of value-based health care. It entails the active engagement of the patients in healthcare ...
Analyzing single cell transcriptome data from severe COVID-19 patients
(2022)
SUMMARY:
We describe the protocol for identifying COVID-19 severity specific cell types and their regulatory marker genes using single-cell transcriptomics data. We construct COVID-19 comorbid disease-associated gene list ...
Computational Analysis of Short Linear Motifs in the Spike Protein of SARS-CoV-2 Variants Provides Possible Clues into the Immune Hijack and Evasion Mechanisms of Omicron Variant
(2022-08)
Abstract:
Short linear motifs (SLiMs) are short linear sequences that can mediate protein–protein interaction. Mimicking eukaryotic SLiMs to compete with extra- or intracellular binding partners, or to sequester host ...