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Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease
(2021)
Abstract:
The geographic location and heterogeneous multi-ethnic population of Dubai (United Arab Emirates; UAE) provide a unique setting to explore the global molecular epidemiology of SARS-CoV-2 and relationship between ...
Effect of Common Medications on the Expression of SARS-CoV-2 Entry Receptors in Kidney Tissue
(2020)
Abstract: Besides the respiratory system, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection was shown to affect other essential organs such as the kidneys. Early kidney involvement during the course ...
Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19
(2020)
Abstract:
The ongoing COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Age, smoking, obesity, and chronic diseases such as cardiovascular disease and diabetes have been described as risk factors for severe ...
Multiple early introductions of SARS‑CoV‑2 into a global travel hub in the Middle East
(2020)
Abstract:
International travel played a significant role in the early global spread of SARS-CoV-2. Understanding transmission patterns from different regions of the world will further inform global dynamics of the pandemic. ...
SEAHIR: A Specialized Compartmental Model for COVID-19
(2021)
Abstract:
The SEIR (Susceptible-Exposed-Infected-Removed) model is widely used in epidemiology to mathematically model the spread of infectious diseases with incubation periods. However, the SEIR model prototype is generic ...
Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening
(2020)
Purpose:
With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive, self-collected specimen like saliva ...
Saliva for molecular detection of SARS-CoV-2 in school-age children
(2021)
Objectives:
The high diagnostic accuracy indices for saliva severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase PCR (RT-PCR) reported in adults has not been demonstrated in children, and ...
Molecular Basis of Cardiac and Vascular Injuries Associated With COVID-19
(2020)
Background:
Coronavirus disease 2019 (COVID-19) is a viral respiratory illness caused by the novel coronavirus SARS-CoV-2. The presence of the pre-existing cardiac disease is associated with an increased likelihood of ...
Coinfections in Patients Hospitalized with COVID-19: A Descriptive Study from the United Arab Emirates
(2021)
Purpose:
Microbial coinfections in COVID-19 patients carry a risk of poor outcomes. This study aimed to characterize the clinical and microbiological profiles of coinfections in patients with COVID-19.
Methods:
A ...