Publication: Acute effects of exercise on macro- and microvasculature in individuals with type 1 diabetes - a secondary outcome analysis
dc.contributor.author | Alnuaimi, Suhaila | |
dc.contributor.author | Goswami, Nandu | |
dc.date.accessioned | 2024-10-08T06:42:30Z | |
dc.date.available | 2024-10-08T06:42:30Z | |
dc.date.issued | 2024-08 | |
dc.description.abstract | Abstract Background: Type 1 diabetes is a chronic autoimmune disease associated with insulin-producing beta cell destruction, declining insulin secretion, and elevated blood glucose. Physical activity improves glycaemic control and cardiovascular health. This study explores acute effects of maximal exhaustion induced by a cardiopulmonary exercise on macro- and microvascular parameters in type 1 diabetes. Methodology: Twenty-five participants with type 1 diabetes (14 males, 11 females), aged 41.4 ± 11.87 years, BMI 23.7 ± 3.08, completed a repeated-measure study. Measurements pre-, post-, 30- and 60-minutes post-exhaustion involved a maximal incremental cardio-pulmonary exercise test. Macro- and microvascular parameters were assessed using VICORDER® and retinal blood vessel image analysis. Repeated measures ANOVA in SPSS (Version 27.0) analysed data. Results: Post-exercise, heart rate increased (p<.001), and diastolic blood pressure decreased (p=.023). Diabetes duration correlated with pulse wave velocity (r=0.418, p=.047), diastolic blood pressure (r=0.470, p=.023), and central retinal arteriolar equivalent (r=0.492, p=.023). Conclusion: In type 1 diabetes, cardiopulmonary exercise-induced exhaustion elevates heart rate and reduces diastolic blood pressure. Future research should explore extended, rigorous physical activity protocols for greater cardiovascular risk reduction. | en_US |
dc.identifier.uri | https://repository.mbru.ac.ae/handle/1/1551 | |
dc.language.iso | en | en_US |
dc.subject | Diabetes mellitus | en_US |
dc.subject | Exercise | en_US |
dc.subject | Haemodynamics | en_US |
dc.subject | Microcirculation | en_US |
dc.subject | Type 1 | en_US |
dc.subject | Vascular stiffness | en_US |
dc.title | Acute effects of exercise on macro- and microvasculature in individuals with type 1 diabetes - a secondary outcome analysis | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | en_US |