Publication: A Case of COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome in Shock Managed by Cytokine Filtration
dc.contributor.author | Lalwani, Priyanka | |
dc.contributor.author | Baskaran, Subashini | |
dc.contributor.author | Saqib, Aqdas | |
dc.contributor.author | ElMesserey, Mohammed | |
dc.contributor.author | Pallavidino, Marco | |
dc.date.accessioned | 2022-07-19T08:43:21Z | |
dc.date.available | 2022-07-19T08:43:21Z | |
dc.date.issued | 2022 | |
dc.description.abstract | Abstract: Multisystem inflammatory syndrome in children (MIS-C) after COVID-19 has been recognized as a complication arising due to cytokine storm. Several management strategies including intravenous immunoglobulin and immunomodulators have been reported. This case report highlights the use of a cytokine filter (oXiris®) in the management of MIS-C. Cytokine filters eliminate cytokines and reduce the demand for vasopressors in patients with other inflammatory conditions. A 7-year-old child with prolonged fever, vomiting, hypotension, elevated inflammatory mediators, and dilatation of coronary arteries on echocardiography was found to have positive SARS-CoV-2 IgG and PCR. He was diagnosed as MIS-C and was managed in the pediatric intensive care unit. He required ventilatory support, vasopressors, and continuous renal replacement therapy (CRRT) with a cytokine filter. He showed marked improvement within 24 hours of initiating CRRT. Cytokine filters may have a potential role in the management of severely ill children due to MIS-C. To our knowledge, this is the first report of successful use of the oXiris® membrane in MIS-C. However, further case series and controlled trials are needed to establish its use in this condition. | en_US |
dc.identifier.other | 204-2022.16 | |
dc.identifier.uri | https://repository.mbru.ac.ae/handle/1/968 | |
dc.language.iso | en | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Pediatric Multisystem Inflammatory Syndrome | en_US |
dc.subject | Cytokine Filtration | en_US |
dc.title | A Case of COVID-19-Associated Pediatric Multisystem Inflammatory Syndrome in Shock Managed by Cytokine Filtration | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | en_US |