Publication: Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health
dc.contributor.author | Banerjee, Yajnavalka | |
dc.date.accessioned | 2023-04-25T09:31:44Z | |
dc.date.available | 2023-04-25T09:31:44Z | |
dc.date.issued | 2022 | |
dc.description.abstract | Abstract: Obesity, type 2 diabetes (T2DM), hypertension (HTN), and Cardiovascular Disease (CVD) often cluster together as “Cardiometabolic Disease” (CMD). Just under 50% of patients with CMD increased the risk of morbidity and mortality right from the beginning of the COVID-19 pandemic as it has been reported in most countries affected by the SARS-CoV2 virus. One of the pathophysiological hallmarks of COVID-19 is the overactivation of the immune system with a prominent IL-6 response, resulting in severe and systemic damage involving also cytokines such as IL2, IL4, IL8, IL10, and interferon-gamma were considered strong predictors of COVID-19 severity. Thus, in this mini-review, we try to describe the inflammatory state, the alteration of the adipokine profile, and cytokine production in the obese state of infected and not infected patients by SARS-CoV2 with the final aim to find possible influences of COVID-19 on CMD and CVD. The immunological-based discussion of the molecular processes could inspire the study of promising targets for managing CMD patients and its complications during COVID-19. | en_US |
dc.identifier.other | 204-2022.134 | |
dc.identifier.uri | https://repository.mbru.ac.ae/handle/1/1182 | |
dc.language.iso | en | en_US |
dc.subject | COVID | en_US |
dc.subject | Molecular | en_US |
dc.subject | Inflammation | en_US |
dc.subject | Diabetes | en_US |
dc.subject | Cardiometabolic | en_US |
dc.title | Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | en_US |