Publication:
Sedation After a Trial of Mixed Amphetamine Salts in a Boy with Attention-Deficit/ Hyperactivity Disorder

dc.contributor.authorAlbanna, Ammar
dc.date.accessioned2021-08-04T07:14:15Z
dc.date.available2021-08-04T07:14:15Z
dc.date.issued2020
dc.description.abstractBackground: Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that manifests in early childhood. Pharmacotherapy, including psychostimulants, is considered the cornerstone of ADHD man¬agement. Although stimulants have been associated with adverse effects, sedation following the administra-tion of an amphetamine-based stimulant is an extremely rare adverse effect. Case Report: We report the case of a 6-year-old boy presenting with ADHD and a history of autism spectrum disorder (ASD). After discussing treatment options with his parents, he was started on a low dose of a methylphenidate med¬ication. He was unable to tolerate the medication due to anorexia, insomnia, and irritability despite multiple adjustments in the dosages. A trial of immediate-release mixed amphetamine salts was initiated, starting from a low dose. The boy developed sedation and lethargy shortly after the administration of this medication. Conclusions: Sedation is a rare adverse drug reaction to mixed amphetamine salts. Clinicians should proactively monitor for the possible adverse effects in patients with ASD and ADHD, including unexpected symptoms such as se¬dation. Reporting of adverse drug reactions should be encouraged to promote the post-marketing surveillance of medications.en_US
dc.identifier.other204-2020.97
dc.identifier.urihttps://repository.mbru.ac.ae/handle/1/408
dc.language.isoenen_US
dc.subjectAmphetamineen_US
dc.subjectAttention Deficit Disorder with Hyperactivityen_US
dc.subjectCentral Nervous System Stimulantsen_US
dc.subjectChild Development Disordersen_US
dc.subjectPervasiveen_US
dc.subjectDextroamphetamineen_US
dc.subjectDrug-Related Side Effects and Adverse Reactionsen_US
dc.subjectCase Reportsen_US
dc.titleSedation After a Trial of Mixed Amphetamine Salts in a Boy with Attention-Deficit/ Hyperactivity Disorderen_US
dc.typeBook chapteren_US
dspace.entity.typePublicationen_US

Files