Publication:
Anti-Inflammatory Effects of Compounds from Echinoderms

dc.contributor.authorGhelani, Hardik
dc.contributor.authorKhursheed, Md
dc.contributor.authorAdrian, Thomas E
dc.contributor.authorJan, Reem Kais
dc.date.accessioned2023-04-25T04:37:51Z
dc.date.available2023-04-25T04:37:51Z
dc.date.issued2022-11
dc.description.abstractAbstract: Chronic inflammation can extensively burden a healthcare system. Several synthetic anti-inflammatory drugs are currently available in clinical practice, but each has its own side effect profile. The planet is gifted with vast and diverse oceans, which provide a treasure of bioactive compounds, the chemical structures of which may provide valuable pharmaceutical agents. Marine organisms contain a variety of bioactive compounds, some of which have anti-inflammatory activity and have received considerable attention from the scientific community for the development of anti-inflammatory drugs. This review describes such bioactive compounds, as well as crude extracts (published during 2010-2022) from echinoderms: namely, sea cucumbers, sea urchins, and starfish. Moreover, we also include their chemical structures, evaluation models, and anti-inflammatory activities, including the molecular mechanism(s) of these compounds. This paper also highlights the potential applications of those marine-derived compounds in the pharmaceutical industry to develop leads for the clinical pipeline. In conclusion, this review can serve as a well-documented reference for the research progress on the development of potential anti-inflammatory drugs from echinoderms against various chronic inflammatory conditions.en_US
dc.identifier.other204-2022.171 Hardik Ghelani
dc.identifier.urihttps://repository.mbru.ac.ae/handle/1/1158
dc.language.isoenen_US
dc.subjectAnti-inflammatory activityen_US
dc.subjectInflammatory pathwaysen_US
dc.subjectMarine drugsen_US
dc.subjectEchinodermen_US
dc.subjectSea cucumberen_US
dc.subjectSea urchinen_US
dc.subjectStarfishen_US
dc.titleAnti-Inflammatory Effects of Compounds from Echinodermsen_US
dc.typeArticleen_US
dspace.entity.typePublicationen_US

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