Publication: Anti-Inflammatory Effects of Compounds from Echinoderms
dc.contributor.author | Ghelani, Hardik | |
dc.contributor.author | Khursheed, Md | |
dc.contributor.author | Adrian, Thomas E | |
dc.contributor.author | Jan, Reem Kais | |
dc.date.accessioned | 2023-04-25T04:37:51Z | |
dc.date.available | 2023-04-25T04:37:51Z | |
dc.date.issued | 2022-11 | |
dc.description.abstract | Abstract: Chronic inflammation can extensively burden a healthcare system. Several synthetic anti-inflammatory drugs are currently available in clinical practice, but each has its own side effect profile. The planet is gifted with vast and diverse oceans, which provide a treasure of bioactive compounds, the chemical structures of which may provide valuable pharmaceutical agents. Marine organisms contain a variety of bioactive compounds, some of which have anti-inflammatory activity and have received considerable attention from the scientific community for the development of anti-inflammatory drugs. This review describes such bioactive compounds, as well as crude extracts (published during 2010-2022) from echinoderms: namely, sea cucumbers, sea urchins, and starfish. Moreover, we also include their chemical structures, evaluation models, and anti-inflammatory activities, including the molecular mechanism(s) of these compounds. This paper also highlights the potential applications of those marine-derived compounds in the pharmaceutical industry to develop leads for the clinical pipeline. In conclusion, this review can serve as a well-documented reference for the research progress on the development of potential anti-inflammatory drugs from echinoderms against various chronic inflammatory conditions. | en_US |
dc.identifier.other | 204-2022.171 Hardik Ghelani | |
dc.identifier.uri | https://repository.mbru.ac.ae/handle/1/1158 | |
dc.language.iso | en | en_US |
dc.subject | Anti-inflammatory activity | en_US |
dc.subject | Inflammatory pathways | en_US |
dc.subject | Marine drugs | en_US |
dc.subject | Echinoderm | en_US |
dc.subject | Sea cucumber | en_US |
dc.subject | Sea urchin | en_US |
dc.subject | Starfish | en_US |
dc.title | Anti-Inflammatory Effects of Compounds from Echinoderms | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | en_US |