Browsing by Subject "Immunity"
Now showing items 1-3 of 3
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
(2020)Introduction: Clinical outcomes of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (COVID-19). Epidemiological studies have ... -
Maintenance of neutralizing antibodies over ten months in convalescent SARS-CoV-2 afflicted patients
(2021)Abstract Knowledge of the level and duration of protective immunity against SARS-CoV-2 after primary infection is of crucial importance for preventive approaches. Currently, there is a lack of evidence on the persistence ... -
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
(2023)Background: We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases ...