Browsing by Author "Senok, Abiola"
Now showing items 21-40 of 46
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Lung Epithelial Cells from Obese Patients Have Impaired Control of SARS-CoV-2 Infection
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Obesity is known to increase the complications of the COVID-19 coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms of SARSCoV-2 infection ... -
Metagenomic Sequencing and Reverse Transcriptase PCR Reveal That Mobile Phones and Environmental Surfaces Are Reservoirs of Multidrug-Resistant Superbugs and SARS-CoV-2
Boucherabine, Syrine; Nassar, Rania; Zaher, Shroque; Mohamed, Lobna; Alqutami, Fatma; Hachim, Mahmood Yaseen; Senok, Abiola (2022)Background: Mobile phones of healthcare workers (HCWs) can act as fomites in the dissemination of microbes. This study was carried out to investigate microbial contamination of mobile phones of HCWs and environmental ... -
Microbial Metabolic Genes Crucial for S. aureus Biofilms: An Insight From Re-analysis of Publicly Available Microarray Datasets
Nassar, Rania; Hachim, Mahmood Yaseen; Kaklamanos, Eleftherios G; Jamal, Mohamed; Senok, Abiola (2021)Abstract: Bacterial biofilms are microbial lifestyles found in all environments. Up to 80% of human infections and 60–70% of hospital-acquired infections have a biofilm origin, with Staphylococcus aureus one of the leading ... -
Mobile phones are hazardous microbial platforms warranting robust public health and biosecurity protocols
Nassar, Rania; Senok, Abiola (2022)Introduction: Advancements in technology and communication have revolutionised the twenty-frst century with the introduction of mobile phones and smartphones. These phones are known to be platforms harbouring microbes ... -
Mobile phones as fomites for pathogenic microbes: A cross-sectional survey of perceptions and sanitization habits of health care workers in Dubai, United Arab Emirates
Nassar, Rania; Boucherabine, Syrine; Senok, Abiola (2022-08)Backgrounds: In 2022, smartphone use continues to expand with the number of smartphone subscriptions surpassing 6 billion and forecasted to grow to 7.5 billion by 2026. The necessity of these ‘high touch’ devices as ... -
Molecular Basis of Cardiac and Vascular Injuries Associated With COVID-19
Hachim, Mahmood Yaseen; Al Heialy, Saba; Senok, Abiola; Alsheikh-Ali, Alawi (2020)Background: Coronavirus disease 2019 (COVID-19) is a viral respiratory illness caused by the novel coronavirus SARS-CoV-2. The presence of the pre-existing cardiac disease is associated with an increased likelihood of ... -
Molecular Characterization of Staphylococcus aureus Isolates Associated with Nasal Colonization and Environmental Contamination in Academic Dental Clinics
Senok, Abiola; Kaklamanos, Eleftherios G; Nassar, Rania; Belhoul, Khawla (2020)Aim: To determine the genetic makeup of methicillin-sensitive/methicillin-resistant Staphylococcus aureus (MSSA/MRSA) from nasal colonization and environmental contamination in dental clinics. Materials and Methods: ... -
Molecular Typing of ST239-MRSA-III From Diverse Geographic Locations and the Evolution of the SCCmec III Element During Its Intercontinental Spread
Senok, Abiola (2018-07-06)Abstract: ST239-MRSA-III is probably the oldest truly pandemic MRSA strain, circulating in many countries since the 1970s. It is still frequently isolated in some parts of the world although it has been replaced by other ... -
Multiple early introductions of SARS‑CoV‑2 into a global travel hub in the Middle East
Tayoun, Ahmad Abou; Loney, Tom; Uddin, Mohammed; Senok, Abiola; Nowotny, Norbert; Alsheikh-Ali, Alawi; Al Suwaidi, Hanan (2020)Abstract: International travel played a significant role in the early global spread of SARS-CoV-2. Understanding transmission patterns from different regions of the world will further inform global dynamics of the pandemic. ... -
N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Kandasamy, Richard K; Al Heialy, Saba (2022)Abstract: Despite the growing number of the vaccinated population, COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global health burden. Obesity, a metabolic syndrome affecting ... -
Novel Markers in Pediatric Acute Lymphoid Leukemia: The Role of ADAM6 in B Cell Leukemia
Alsuwaidi, Laila; Hachim, Mahmood Yaseen; Senok, Abiola (2021)Background: The extensive genetic heterogeneity found in the B cell precursor acute lymphoblastic leukemia (BCP-ALL) subtype of childhood ALL represents a potential repository of biomarkers. To explore this potential, ... -
Phytic Acid Demonstrates Rapid Antibiofilm Activity and Inhibits Biofilm Formation When Used as a Surface Conditioning Agent
Nassar, Rania; Senok, Abiola (2023)Abstract: Root canal infections are associated with biofilms and are treated with chemical irrigants with a high success rate. However, treatment failure does arise, which is attributed primarily to resistance exhibited ... -
A pilot metagenomic study reveals that community derived mobile phones are reservoirs of viable pathogenic microbes
Senok, Abiola; Nassar, Rania (2021)Abstract: There is increasing attention focussed on the risks associated with mobile phones possibly serving as ‘Trojan Horse’ fomites for microbial transmission in healthcare settings. However, little is reported on the ... -
Polycystic Ovary Syndrome and Endometrial Cancer: A Scoping Review of the Literature on Gut Microbiota
Prakash, Amog; Nourianpour, Milad; Senok, Abiola; Atiomo, William (2022)Abstract: Gut dysbiosis has been associated with polycystic ovary syndrome (PCOS) and endometrial cancer (EC) but no studies have investigated whether gut dysbiosis may explain the increased endometrial cancer risk in ... -
Prevalence and Factors Associated with Methicillin‑Resistant Staphylococcus aureus Colonization among Clinical Medical Students
Senok, Abiola (2019)Background: This study was carried out to assess the prevalence and determinants of methicillin‑resistant Staphylococcus aureus (MRSA) colonization among clinical clerkship medical students in Saudi Arabia. Methods: A ... -
The prevalence of novel periodontal pathogens and bacterial complexes in Stage II generalized periodontitis based on 16S rRNA next generation sequencing
Senok, Abiola (2021)Objective: To define the subgingival microbial profile associated with Stage II generalized periodontitis using next-generation sequencing and to determine the relative abundance of novel periodontal pathogens and bacterial ... -
Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19
Al Heialy, Saba; Hachim, Mahmood Yaseen; Senok, Abiola; Tayoun, Ahmad Abou; Alsheikh-Ali, Alawi (2020)Abstract: The ongoing COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Age, smoking, obesity, and chronic diseases such as cardiovascular disease and diabetes have been described as risk factors for severe ... -
Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening
Senok, Abiola; Alsuwaidi, Hanan; Han, Aaron; Al Heialy, Saba; Loney, Tom; Alsheikh-Ali, Alawi (2020)Purpose: With the easing of restriction measures, repeated community-based sampling for tracking new COVID-19 infections is anticipated for the next 6 to 12 months. A non-invasive, self-collected specimen like saliva ... -
Saliva for molecular detection of SARS-CoV-2 in school-age children
Al Suwaidi, Hanan; Senok, Abiola; Loney, Tom; Alsheikh-Ali, Alawi (2021)Objectives: The high diagnostic accuracy indices for saliva severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcriptase PCR (RT-PCR) reported in adults has not been demonstrated in children, and ... -
SEAHIR: A Specialized Compartmental Model for COVID-19
Senok, Abiola; Alsheikh-Ali, Alawi; Loney, Tom (2021)Abstract: The SEIR (Susceptible-Exposed-Infected-Removed) model is widely used in epidemiology to mathematically model the spread of infectious diseases with incubation periods. However, the SEIR model prototype is generic ...