Hamdan Bin Mohammed College of Dental Medicine (HBMCDM)

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Browsing Hamdan Bin Mohammed College of Dental Medicine (HBMCDM) by Subject "(RMGIC) varnish"

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    The effect of layered double hydroxide on fluoride release and recharge from a commercial and an experimental resin varnish
    (2021) Tejani, Tameeza Hassanali; Milosevic, Alex
    Objectives: Layered Double Hydroxide (LDH) is capable of fluoride anion exchange and release. This study investigated the effects of incorporating ZnAl-LDH in commercial and experimental dental varnishes, on fluoride release and re-release after charging in NaF. Methods: Five discs of each material (commercial ClinproXT varnish and experimental light cured resin varnish), with and without 9%ZnAl-LDH were immersed and agitated in deionised water (DW) at 37◦C. A fluoride ion selective electrode measured fluoride release in DW daily over two-weeks. At 3, 6, 9 and 12 days the discs were recharged in 15 ml 0.05 M NaF solution (37◦C) for five minutes followed by immersion in DW. Energy dispersive X-rayspectra (EDS), weight changes and SEMs were performed on discs, before and after each cycle. Results: Evidence of ZnAl-LDH was confirmed by the presence of peaks for zinc and aluminium in EDS spectra. Cumulative fluoride and mean fluoride released between Clinpro, Clinpro + LDH and resin were significantly different (ANOVA, Tukey’s HSD post-hoc test, p< 0.001) except between the resin and resin + LDH. Mean fluoride concentrations differed significantly after every recharge between Clinpro, Clinpro + LDH and resin, but not betweenthe resin and resin + LDH (p < 0.01). The weights and SEMs of the experimental resins +/-LDH, appeared to be stable whilst the weights of Clinpro samples +/−LDH, fluctuated and fragmented. Significance: ClinproXT and experimental resin containing ZnAl-LDH recharged with fluoride did not significantly increase fluoride release compared to the unmodified materials. However, all LDH-F incorporated materials demonstrated fluoride recharging properties which appear beneficial to dentistry and thus further work is required to improve these properties.