Publications (GME)

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Browsing Publications (GME) by Subject "case report"

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    Acquired methemoglobinemia in infancy secondary to diarrhea: a case report.
    (2024-09) Aly, Mariam Hany; Bukhari, Hessa Mohammed
    Methemoglobinemia (MetHb) is a life-threatening condition that reduces the oxygen-carrying ability of hemoglobin. Acquired methemoglobinemia usually results from exposure to specific oxidizing agents. Symptoms and complications depend on the MetHb level, which can sometimes be fatal. We present a case of a 6-week-old infant exhibiting hypoxia alongside gastroenteritis, fever, poor oral intake and low activity, with confirmed methemoglobinemia in blood gas analysis. Despite negative results in the workup for underlying causes, including genetic testing conducted later, methylene blue administration only partially reduced methemoglobinemia level. Treatment involved managing diarrhea by transitioning to a hydrolyzed formula. Interestingly, an incidental discovery of partial central venous sinus thrombosis occurred during the diagnostic process, although no established correlation with methemoglobinemia was evident in the literature. This case report illustrates the complex presentation of methemoglobinemia in a previously healthy infant, occurring concurrently with gastrointestinal infection and unexpected thrombosis. It underscores the need for interdisciplinary collaboration and comprehensive management in addressing such multifaceted clinical scenarios in pediatric practice. This case emphasizes the importance of considering diarrhea as a possible cause of methemoglobinemia, especially in infancy. It also highlights the need for increased clinical awareness and prompt management approaches towards the various presentations of acquired methemoglobinemia in pediatric populations.
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    Osteomyelitis of the Patella With Extension Into Parapatellar Soft Tissues in a Six-Year-Old Boy: A Case Report
    (Springer Science and Business Media LLC, 2024-11-07) Abdelwahab, Abdulla; Nidal, Abdulla
    Acute osteomyelitis (OM) of the patella is an exceptionally rare condition in children. The rarity of this condition, coupled with its nonspecific symptoms and varied clinical presentations, makes early diagnosis challenging and often results in delayed treatment. Prompt identification and initiation of antibiotic therapy are essential for a full recovery and to prevent the disease from progressing to a chronic, more severe form. This case report discusses a previously healthy six-year-old boy who developed OM of the left patella following a fall from standing height after tripping three days prior to his presentation at the emergency department. Due to the unusual and infrequent nature of patellar OM, it is often overlooked as a potential cause of knee pain in pediatric patients. Clinicians must consider patellar OM in the differential diagnosis for children presenting with knee pain. Accurate and timely diagnosis relies on thorough clinical assessments, laboratory testing, and appropriate imagining techniques (i.e., X-ray and magnetic resonance imaging (MRI)). Early identification and appropriate treatment are critical in preventing the infection from spreading within the joint and ensuring a favorable outcome.