Browsing by Author "Maideen, Naina Mohamed Pakkir"

Now showing 1 - 1 of 1

Clinical insights on the complications of TPM use during pregnancy-enabling expectant mothers to make informed choices for their health and the future of their offspring
(2025-07-24) Maideen, Naina Mohamed Pakkir
Background: Topiramate (TPM) is a new-generation, broad-spectrum anti-seizure drug with a unique structure compared to other anti-epileptic medications. It is widely used for epilepsy treatment, migraine prevention, and weight management in overweight or obese individuals. Additionally, it has off-label applications in conditions such as alcohol use disorder, binge eating disorder, and neuropathic pain. TPM exerts its therapeutic effects through multiple mechanisms, including the inhibition of voltage-gated ion channels and the enhancement of GABAergic neurotransmission.