Browsing by Author "Jaber, Mohamed A"

Now showing 1 - 5 of 5

Biopsy Procedures in Oral Maxillofacial Practice: An Update
(2016) Jaber, Mohamed A
Abstract: Biopsy is a necessary diagnostic tool to confirm the clinical diagnosis and to make diagnosis itself based on microscopy. For microscopic examination it is necessary to provide a representative sample of the lesion to interpret proper histopathological diagnosis. Present article is an attempt to update the various biopsy techniques in various oral disorders. We also emphasized on the need of careful handling of the specimens to avoid any artefacts in histological sections in order to obtain an accurate diagnosis.
Evaluation of Calcified Carotid Artery Atheromas Detected By Panoramic Radiograph among Patients with Type II Diabetes Mellitus
(2015) Jaber, Mohamed A; Shah, Maanas S.; Abuzayda, Moosa
Abstract: This study was designed to determine the prevalence of Carotid artery calcifications (CACs) of diabetic patients and compare it with normal non-diabetic individuals. Panoramic radiographs of 200 adult patients with type 2 diabetes (90 male and 110 females) (age range 16-79 years; mean age 40.54 years) and 200 controls (age-match, free of systemic diseases) were examined on panoramic radiographs for any unusual radiopacity adjacent to or just below the intervertebral space between C3 and C4. Statistical analysis was carried out using chi-squared and Fisher exact tests. Carotid artery calcifications (CACs) were higher in diabetic patients compared with normal healthy control and the statistical difference between the two groups was significant (Chi-square test = 10.82, P = 0.001). Twenty-five (16 females, 9 males) diabetic patients showed CACs, Mean age of diabetic patients with calcification was 47.11 years. Further analysis of this group showed that 60% of patients with CACs were smokers, 48% had hypertension and 25% were obese. In conclusion, our study shows that in patients with diabetes mellitus CACs can be detected by panoramic radiography and the patients may benefit from a referral to physicians for further evaluation and necessary management.
Guerin sign in midfacial fractures
(2016-05-31) Jaber, Mohamed A
Abstract: We report a patient with multiple fractures of the midface and Guerin sign bilaterally after maxillofacial trauma. To the best of our knowledge, this is the first time that this rare presentation of Guerin sign has been published.
Hematinic Deficiency and the risk of Oral Epithelial Dysplasia
(2017-10-21) Jaber, Mohamed A
Abstract: Oral squamous cell carcinoma could be preceded by clinically evident oral potentially malignant disorders harboring oral epithelial dysplasia (OED. Hematinic deficiencies are associated with certain potentially malignant disorders and cancerous lesions. The aims of this study were: to evaluate the circulating levels of vitamin B12, folate status in patients with OED and to assess the impact tobacco smoking on these levels. To evaluate the circulating level of vitamin B12, serum folate, red blood cells folate among OED patients. Data were collected from 120 patients with OED and 120 healthy control Subjects matched for age and gender, selected from patients with oral diseases not caused by tobacco or alcohol or related to knowing hematinic deficiency. Most of patients with OED were current smokers of more than 20 cigarettes per day for more than 20 years compared with normal healthy control. A significant decrease in the serum levels of folate, red blood cell folate was found in OED compared to normal tobacco smokers (p<0.05). No significant differences in vitamin B12 was found between OED cases and normal control subjects. These findings support the notion that OED may develop in persons who expose to tobacco smoking and have low folate level.
Serum levels of folate and vitamin B12 in oral epithelial dysplasia
(2015) Jaber, Mohamed A
Abstract: Oral epithelial dysplasia (OED) is a histopathologic diagnosis associated with an increased risk of cancer. Deficiency of vitamin B12 and folate is associated with causation of certain precancerous and cancerous lesions. The aims of this study were: to evaluate the circulating levels of vitamin B12, folate status and iron, in patients with OED and to compare these levels with the values obtained in normal control subjects with and without tobacco smoking and alcohol drinking. To evaluate the circulating level of vitamin B12, serum folate, red blood cells folate and iron among OED patients. Data were collected from 120 patients with OED and 120 healthy control Subjects matched for age and gender, selected from patients with oral diseases not caused by tobacco or alcohol or related to knowing haematinic deficiency. Measurement of serum folate and vitamin B12 were carried out using radioassay. The majority of OED were graded either mild (46.7%) or moderate (40.0%) lesions and most of patients with OED were current smokers of more than 20 cigarettes per day for more than 20 years compared with normal healthy control. A significant decrease in the serum levels of folate, red blood cell folate was found in OED compared to normal tobacco smokers (p<0.05). No significant differences in vitamin B12 was found between OED cases and normal control subjects. Likewise significant differences in serum ferritin level were found between OED cases and normal drinkers of alcoholic beverages (p<0.05). And no significant differences in the TIBC level in OED compared with control subjects. These findings support the notion that OED may develop in persons who expose to tobacco smoking and have low folate level. A possible inverse association between iron concentrations and the risk of OED needs further study.