Browsing by Author "Al-Saqi, Reem Kais"

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Are asthma and airway allergy associated with increased root resorption following orthodontic treatment? A systematic review
(2020) Al-Saqi, Reem Kais
Aim: Asthma and airway allergy have been implicated with root resorption development following orthodontic treatment. The objective of this study was to investigate systematically the relevant literature. Materials and Methods: Search without restrictions for published and unpublished literature and hand searching took place. Data on root resorption in patients with asthma or allergy having undergone comprehensive orthodontic treatment were reviewed. The risk of bias was assessed using the Newcastle-Ottawa Scale. Results: From the initially retrieved records, three cohort and two case-control studies met the inclusion criteria. The studies reported conflicting results and the risk of bias assessment revealed shortcomings in various domains. Conclusions: The information regarding the association of asthma and airway allergy with root resorption following orthodontic treatment is contradictory and further research is warranted. However, until more data become available good practice would suggest that it is important to identify patients with asthma or airway allergy and consider the possible implications.
Are asthma and allergy associated with increased root resorption following orthodontic treatment? A meta-analysis
(2023) Al-Saqi, Reem Kais; Athanasiou, Athanasios E; Kaklamanos, Eleftherios G
Objective: The aim of this study is to systematically investigate the available evidence from human studies regarding the association of asthma and/or allergy with EARR. Materials and methods: Unrestricted searches in 6 databases and manual searching were performed up to May 2022. We looked for data on EARR after orthodontic treatment in patients with/without asthma or allergy. Relevant data were extracted, and the risk of bias was assessed. An exploratory synthesis was carried out using the random effects model, and the overall quality of the evidence was assessed with the Grades of Recommendation, Assessment, Development, and Evaluation. Results: From the initially retrieved records, nine studies met the inclusion criteria (three cohort and six case-control). Overall, increased EARR was observed in the individuals with allergies in their medical history (Standardised Mean Difference [SMD]: 0.42, 95% Confidence Interval [CI]: 0.19 to 0.64). No difference in EARR development was observed among individuals with or without a medical history of asthma (SMD: 0.20, 95% CI: -0.06 to 0.46). The quality of available evidence, excluding studies at high risk, was rated as moderate for the exposure to allergy, and low for the exposure to asthma. Conclusion: Increased EARR was noted in individuals with allergies compared to the control group, while no difference was observed for individuals with asthma. Until more data become available, good practice would suggest that it is important to identify patients with asthma or allergy and consider the possible implications.