MBRU Knowledge Repository
Knowledge Repository at Mohammed Bin Rashid University of Medicine and Health Sciences
Welcome to digital archive and research repository of Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU). MBRU Knowledge Repository is a digital service that collects, preserves, and distributes digital material. MBRU's scholarly communications including theses, faculty publications, student projects, and departmental records and publications are the key digital records available in this repository. Repositories are important tools for preserving an organization's legacy; they facilitate digital preservation and scholarly communication.
University users are requested to log-in to view the full-text.
Communities in DSpace
Select a community to browse its collections.
- Library Digital Archives
- Research and Scholarly work of College of Medicine
- Dubai Health Researchers Profiles
- Research and Scholarly work of Graduate Medical Education
- Research and Scholarly work of Hamdan Bin Mohammed College of Dental Medicine
- Research and Scholarly work of Hind Bint Maktoum College of Nursing and Midwifery
- Research and Scholarly work of IoL
- Research publications of other departments
- Theses and dissertations submitted by MBRU graduate and post-graduate students.
Recent Submissions
Exploring Nurses Perceptions and Beliefs Regarding the Causes of Medication Errors
(2022) Bilal, Amina Masood Bilal Mohammad
Abstract:
Background:
Patient safety is a fundamental challenge facing health organizations worldwide. Medication safety is a crucial element that falls under patient safety. Therefore, errors in medication administration may be directly associated with mortality and morbidity. This systematic review aims to explore nurses' perceptions and beliefs regarding the causes of medication errors.
Methods:
Three databases were utilized for systematic search through Mohammed Bin Rashid Medicine and Health Sciences University Library to access CINAHL, PubMed, and Medline. Additional data was sourced by cross-referencing in-text citations to collate the best available evidence exploring nurses' perceptions and beliefs regarding the causes of medication errors. Twelve articles were critically appraised, utilizing the Critical Appraisal Skills Program checklist (CASP).
Results:
Four themes were synthesized from a critical evaluation of the literature. These themes are -nurses believe that medication errors are primarily caused by - poor communication, staff shortage, poor skill mix and/or heavy workload, nurses' lack knowledge of the medication process, and when certain environmental factors are present.
Conclusion:
There were various causes for medication administration errors in nurses' perceptions and beliefs. This means an essential enhancement in medication safety is likely to require multiple, inter-relating, complex interventions, and attention to nurses' perceptions as they play a significant role in enhancing medication safety. Due to the lack of current research on this subject in the Middle East, more research should be conducted to examine medication safety in this part of the world.
Multidisciplinary orthodontic and prosthetic treatment of an eleven year old patient with a solitary median maxillary central incisor: A case report
(2025-10-07) Athanasiou, Athanasios E; Kaklamanos, Eleftherios G
Solitary median maxillary central incisor (SMMCI) syndrome is a rare developmental disorder in which a patient presents with only one upper central incisor located in the midline, along with some other features - such as deviant sella turcica and pituitary gland morphology, panhypopituitarism, hypothyroidism, and hypoplasia of the inner genitals - that may or may not be present. Although some authors consider it a mild manifestation of holoprosencephaly, others classify it as a distinct entity. The aim of this case report is to describe the orthodontic treatment of an 11-year-old female patient with SMMCI. The patient presented with early permanent dentition, Class II, division 2, subdivision (left) malocclusion on a Class I skeletal pattern, a solitary median maxillary central incisor, and moderate crowding in the lower dental arch. Orthodontic treatment was carried out using fixed appliances, involving the creation of space for an additional maxillary central incisor and the correction of Class II malocclusion through the application of intermaxillary elastics. By the end of treatment, Class I canine and molar relationships had been achieved, the overjet and overbite became optimal, and a one-wing Maryland bridge was placed in the area of the left maxillary central incisor. Regarding retention, a lower fixed retainer from canine to canine and upper and lower vacuum-formed appliances were used. In conclusion, this case report highlights the importance of coordinated care among dental specialists for effectively treating solitary median maxillary central incisor cases.
Epidemiological and histopathological spectrum of gastrointestinal tract disorders: a decade of records from the UAE
(2025-09-29) Alsaad, Latifa Nabeel
Background: Gastrointestinal (GI) disorders represent a major public health concern, yet data from the UAE remain limited, particularly regarding histopathological trends. This study aimed to characterize the epidemiological spectrum and distribution of GI disorders reported to a tertiary care pathology center over a ten-year period. Histopathology-based surveillance offers unique insight into tissue-level patterns often missed by clinical registries.
Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study.
(2025-09-28) Kowash, Mawlood; Abdalla, Mustafa
Objectives: Assess the treatment outcomes and pain relief afforded by full pulpotomy in vital primary molars with clinical symptoms indicative of irreversible pulpitis.
Cenani-Lenz syndrome: a case of De Novo dual LRP4 mutations
(Springer Science and Business Media LLC, 2025-09-28) Salam, Donna
Background: Cenani-Lenz syndrome (CLS) is a rare autosomal recessive disorder that causes malformation in limb development most commonly affecting the hands and feet, along with variable craniofacial and renal anomalies. This condition results from mutations in the LRP4 gene, disrupting a critical signaling pathway essential for limb and organ development. CLS has been reported in families from the Middle East and South Asia, with our case adding to its occurrence in Africa.
Case presentation: We report a case of a 5-year-old Sudanese male, the first-born child of consanguineous parents, presenting with severe bilateral hand and foot deformities, including complex syndactyly, oligodactyly, absent thumbs, and facial dysmorphism. The radiographs revealed bilateral complex deformities of the hands and feet, including shortened and disorganized metacarpals and phalanges, with features of syndactyly and ectrodactyly. The left hand showed only three abnormally shaped phalanges, while both feet exhibited reduced metatarsal counts and dysplastic, fused toe bones. He had no delay in developmental milestones or renal involvement. Whole-exome sequencing identified compound heterozygous variants in LRP4 which were a frameshift mutation (c.3813del; p.Thr1272Leufs*18) classified as likely pathogenic, and a missense mutation (c.4910G > A; p.Cys1637Tyr) of uncertain significance. The patient underwent multiple surgical interventions to his hands, however, significant functional limitations persist.
Conclusions: This case expands on the clinical spectrum of CLS and highlights its presence in African populations, reinforcing the importance of considering CLS as a differential diagnosis of complex limb malformations in regions with high consanguinity by supporting the integration of genetic testing into early diagnostic pathways for limb malformations. Given its significant impact on daily function, early genetic diagnosis and a multidisciplinary management approach are crucial for optimizing outcomes, particularly in families with a history of limb malformations.
Our findings: Enabling more accurate classification and timely intervention. Distinguishing CLS from other limb malfunction syndromes through genetic testing is essential.