Publication:
Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients

dc.contributor.authorHachim, Mahmood Yaseen
dc.date.accessioned2021-08-04T06:47:33Z
dc.date.available2021-08-04T06:47:33Z
dc.date.issued2020
dc.description.abstractAbstract: Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population. Methods: A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury. Results: During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death. Conclusion: Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multiorgan damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended.en_US
dc.identifier.other204-2020.76
dc.identifier.urihttps://repository.mbru.ac.ae/handle/1/388
dc.language.isoenen_US
dc.subjectCardiac injuryen_US
dc.subjectCorona virusen_US
dc.subjectCOVID-19en_US
dc.subjectAcute respiratory distress syndromeen_US
dc.subjectMortalityen_US
dc.titleAcute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patientsen_US
dc.typeArticleen_US
dspace.entity.typePublicationen_US

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