Browsing by Subject "ACE2"
Now showing items 1-4 of 4
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Cardiovascular medications and regulation of COVID-19 receptors expression
(2020)Introduction: Emerging epidemiological studies suggested that Renin–Angiotensin–Aldosterone system (RAAS) inhibitors may increase infectivity and severity of COVID-19 by modulating the expression of ACE2. Methods: ... -
Effect of common medications on the expression of SARS‑CoV‑2 entry receptors in liver tissue
(2020)Abstract: Besides lung drastic involvement, SARS-CoV-2 severely affected other systems including liver. Emerging epidemiological studies brought the attentions towards liver injury and impairment as a potential outcome ... -
Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors
(2020)Abstract: Cellular entry of SARS-CoV-2 is thought to occur through the binding of viral spike S1 protein to ACE2. The entry process involves priming of the S protein by TMPRSS2 and ADAM17, which collectively mediate the ... -
Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19
(2020)Abstract: The ongoing COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Age, smoking, obesity, and chronic diseases such as cardiovascular disease and diabetes have been described as risk factors for severe ...