Browsing by Author "Senok, Abiola"
Now showing items 1-20 of 55
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ACE2 polymorphisms impact COVID-19 severity in obese patients
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2022-12)Abstract: A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. ... -
Antimicrobial Activity of Phytic Acid: An Emerging Agent in Endodontics
Nassar, Rania; Naidoo, Nerissa; Kaklamanos, Eleftherios G; Senok, Abiola (2021)Background: Phytic acid (IP6) is a promising and emerging agent, and because of its unique structure and distinctive properties, it lends itself to several applications in dentistry. Recently, IP6 was proposed as a potential ... -
Antimicrobial resistance in Streptococcus pneumoniae: a retrospective analysis of emerging trends in the United Arab Emirates from 2010 to 2021
Senok, Abiola (2023-11)Abstract: Introduction: Although pneumococcal conjugate vaccines (PCV) have been effective in reducing the burden of Streptococcus pneumoniae infections, there is a paucity of data on the relationship with antimicrobial ... -
Carbapenem resistant Enterobacterales in the United Arab Emirates: a retrospective analysis from 2010 to 2021
Senok, Abiola (2023-12)Abstract: Background: Carbapenem-resistant Enterobacterales (CRE) are spreading in the United Arab Emirates (UAE) where their dissemination is facilitated by international travel, trade, and tourism. The objective of this ... -
Cell free ACE2 RNA: A potential biomarker of COVID-19 severity
Jalaleddine, Nour; Hachim, Mahmood; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Despite the downward trend of COVID-19 pandemic and increased immunity of the general population, COVID19 is still an elusive disease with risks due to emerging variants. Fast and reliable diagnosis of COVID-19 ... -
Characterisation of S. aureus/ MRSA CC1153 and review of mobile genetic elements carrying the fusidic acid resistance gene fusC
Nassar, Rania; Senok, Abiola (2021)Abstract: While many data on molecular epidemiology of MRSA are available for North America, Western Europe and Australia, much less is known on the distribution of MRSA clones elsewhere. Here, we describe a poorly known ... -
Clinical Impact of the BIOFIRE Blood Culture Identification 2 Panel in Adult Patients with Bloodstream Infection: A Multicentre Observational Study in the United Arab Emirates
Senok, Abiola; Olowoyeye, Victory (2023)Abstract: Rapid pathogen identification is key to the proper management of patients with bloodstream infections (BSIs), especially in the intensive care setting. This multicentre study compared the time to pathogen ... -
Clinical Impact of the BIOFIRE Blood Culture Identification 2 Panel in Adult Patients with Bloodstream Infection: A Multicentre Observational Study in the United Arab Emirates
Senok, Abiola; Olowoyeye, Victory (2023)Abstract: Rapid pathogen identification is key to the proper management of patients with bloodstream infections (BSIs), especially in the intensive care setting. This multicentre study compared the time to pathogen ... -
Coinfections in Patients Hospitalized with COVID-19: A Descriptive Study from the United Arab Emirates
Senok, Abiola; Nassar, Rania; Hachim, Mahmood Yaseen; Al Suwaidi, Hanan; Alsheikh-Ali, Alawi (2021)Purpose: Microbial coinfections in COVID-19 patients carry a risk of poor outcomes. This study aimed to characterize the clinical and microbiological profiles of coinfections in patients with COVID-19. Methods: A ... -
COVID-19 Transcriptomic Atlas: A Comprehensive Analysis of COVID-19 Related Transcriptomics Datasets
Alqutami, Fatma; Senok, Abiola; Hachim, Mahmood Yaseen (2021)Background: To develop anti-viral drugs and vaccines, it is crucial to understand the molecular basis and pathology of COVID-19. An increase in research output is required to generate data and results at a faster rate, ... -
Detection of Clostridium difficile antigen and toxin in stool specimens: Comparison of the C. difficile quik chek complete enzyme immunoassay and GeneXpert C. difficile polymerase chain reaction assay
Senok, Abiola (2017)Background/Aims: Accurate and rapid laboratory diagnosis of Clostridium difficile infections (CDI) remains a significant challenge. A two‑step algorithm for detection of toxigenic C. difficile in stool based on initial ... -
The Effect of Chlorhexidine on Bacterial Contamination of Hall Technique Elastomeric Orthodontic Separators and Gingival Health: A Pilot Study
AlNoman, Nada; Al Halabi, Manal; Kowash, Mawlood; Hassan Khamis, Amar; Salami, Anas; Senok, Abiola; Nassar, Rania; Hussein, Iyad (2023)Objective: To study the effect of chlorhexidine on elastomeric orthodontic separators (EOS) bacterial-colonisation and gingival-health in Hall technique (HT) patients. Material and Methods: Prospective invivo pilot ... -
Effect of Common Medications on the Expression of SARS-CoV-2 Entry Receptors in Kidney Tissue
Tayoun, Ahmad Abou; Loney, Tom; Uddin, Mohammed; Senok, Abiola; Al Heialy, Saba; Alsheikh-Ali, Alawi (2020)Abstract: Besides the respiratory system, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection was shown to affect other essential organs such as the kidneys. Early kidney involvement during the course ... -
Emergence of highly resistant Candida auris in the United Arab Emirates: a retrospective analysis of evolving national trends
Senok, Abiola (2024-01)Abstract: Introduction: The Centers for Disease Prevention and Control lists Candida auris, given its global emergence, multidrug resistance, high mortality, and persistent transmissions in health care settings as one of ... -
An emerging Panton-Valentine leukocidin (PVL)-positive CC5-meticillin-resistant Staphylococcus aureus-IVc clone recovered from hospital and community settings over a 17-year period from 12 countries investigated by whole-genome sequencing
Senok, Abiola (2022-12)Background: A novel Panton-Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC)5-MRSA-IVc ('Sri Lankan' clone) was recently described from Sri Lanka. Similar isolates ... -
Epidemiology and antimicrobial resistance trends of Acinetobacter species in the United Arab Emirates: a retrospective analysis of 12 years of national AMR surveillance data
Senok, Abiola (2023-12)Abstract: Introduction: Acinetobacter spp., in particular A. baumannii, are opportunistic pathogens linked to nosocomial pneumonia (particularly ventilator-associated pneumonia), central-line catheter-associated blood ... -
Epidemiology of vancomycin-resistant enterococci in the United Arab Emirates: a retrospective analysis of 12 years of national AMR surveillance data
Senok, Abiola (2023)Introduction: Enterococci are usually low pathogenic, but can cause invasive disease under certain circumstances, including urinary tract infections, bacteremia, endocarditis, and meningitis, and are associated with ... -
Evolving trends among Pseudomonas aeruginosa: a 12-year retrospective study from the United Arab Emirates
Senok, Abiola (2023-11)Abstract: Introduction: Pseudomonas is a group of ubiquitous non-fermenting Gram-negative bacteria (NFGNB). Of the several species associated with humans, Pseudomonas aeruginosa (PA) can acclimate to diverse environments. ... -
First Report of blaCTX-M-28 in Enterobacteriaceae Isolates in the United Arab Emirates
Senok, Abiola (2018)Background: The CTX-M family of extended-spectrum beta lactamase (ESBL) enzymes is comprised of over 60 𝑏𝑙𝑎CTX-M gene variants with the predominance of 𝑏𝑙𝑎CTX-M-15 in many regions. In this report, we present the ... -
Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease
Loney, Tom; Al Suwaidi, Hanan; Uddin, Mohammed; Senok, Abiola; Nowotny, Norbert; Alsheikh-Ali, Alawi; Tayoun, Ahmad Abou (2021)Abstract: The geographic location and heterogeneous multi-ethnic population of Dubai (United Arab Emirates; UAE) provide a unique setting to explore the global molecular epidemiology of SARS-CoV-2 and relationship between ...