Browsing by Author "Rizzo, Manfredi"
Now showing items 1-12 of 12
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The effect of sodium-glucose co-transporter-2 inhibitors on markers of subclinical atherosclerosis
Rizzo, Manfredi (2023-12)Abstract: Background: Despite the widespread use of classical cholesterol-lowering drugs to mitigate the adverse impacts of dyslipidaemia on atherosclerosis, many patients still face a substantial residual risk of developing ... -
The Effect of Sodium-Glucose Cotransporter Inhibitors on Renal Function as Adjunctive to Insulin in Adults with Type 1 Diabetes: An Updated Multilevel Meta-analysis of Randomized Controlled Trials
Rizzo, Manfredi (2024-01)Abstract: Introduction: This systematic review aimed to summarize the existing evidence from published randomized controlled trials (RCTs) on the impact of sodium-glucose cotransporter (SGLT) inhibitors on albuminuria ... -
Efficient Generation of Chondrocytes From Bone Marrow–Derived Mesenchymal Stem Cells in a 3D Culture System: Protocol for a Practical Model for Assessing Anti-Inflammatory Therapies
Patnaik, Rajashree; Jannati, Shirin; Rizzo, Manfredi; Naidoo, Nerissa; Banerjee, Yajnavalka (2023)Background: Chondrocytes are the primary cells responsible for maintaining cartilage integrity and function. Their role in cartilage homeostasis and response to inflammation is crucial for understanding the progression ... -
Efficient Generation of Chondrocytes From Bone Marrow–Derived Mesenchymal Stem Cells in a 3D Culture System: Protocol for a Practical Model for Assessing Anti-Inflammatory Therapies
Patnaik, Rajashree; Jannati, Shirin; Rizzo, Manfredi; Naidoo, Nerissa; Banerjee, Yajnavalka (2023)Background: Chondrocytes are the primary cells responsible for maintaining cartilage integrity and function. Their role in cartilage homeostasis and response to inflammation is crucial for understanding the progression ... -
GLP-1 and dual GIP/GLP-1 receptor agonists in overweight/obese patients for atherosclerotic cardiovascular disease prevention: Where are we now?
Rizzo, Manfredi (2023)Introduction: Obesity is a highly prevalent chronic disease characterized by an increase of body fat stores.1 Increased adiposity (body fat), particularly abdominal/visceral fat, plays a role in altering immune and ... -
Glucagon-Like Peptide-1 Receptor Agonists and Dual Glucose-Dependent Insulinotropic Polypeptide/Glucagon-Like Peptide-1 Receptor Agonists in the Treatment of Obesity/Metabolic Syndrome, Prediabetes/Diabetes and Non-Alcoholic Fatty Liver Disease-Current Evidence
Mikhailidis, Dimitri P; Rizzo, Manfredi (2022-12)Abstract: The obesity pandemic is accompanied by increased risk of developing metabolic syndrome (MetS) and related conditions: non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH), type 2 diabetes ... -
New Onset Diabetes Mellitus in COVID-19: A Scoping Review
Banerjee, Yajnavalka; Mikhailidis, Dimitri P.; Rizzo, Manfredi (2024)Background: Higher education institutions need to put change management as a pivotal part of their strategy. The challenge is to effectively contextualize existing change management models to the respective work environment. ... -
Obesity and nonalcoholic fatty liver disease in type 1 diabetes mellitus patients
Rizzo, Manfredi; Mikhailidis, Dimitri P (2022-11)Introduction: Assessed the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with type 1 diabetes mellitus (T1DM). They included 15 children with T1DM and obesity, 34 children with T1DM but no obesity and ... -
Personalized management of dyslipidemias in patients with diabetes-it is time for a new approach (2022)
Rizzo, Manfredi (2022)Abstract: Dyslipidemia in patients with type 2 diabetes (DMT2) is one of the worst controlled worldwide, with only about 1/4 of patients being on the low-density lipoprotein cholesterol (LDL-C) target. There are many ... -
The role of atherogenic lipoproteins in diabetes: Molecular aspects and clinical significance
Banerjee, Yajnavalka; Vichithran, Suhina; Faisal, Shemima; Rizzo, Manfredi (2023)Abstract: Dyslipidaemia plays a prominent role in the genesis of atherosclerotic plaque and the increased cardiovascular risk in diabetes. Macrophages readily take up atherogenic lipoproteins, transforming into foam cells ... -
Telemedicine for diabetes management during COVID-19: what we have learnt, what and how to implement
Banerjee, Yajnavalka; Rizzo, Manfredi (2023)Abstract: The past two decades have witnessed telemedicine becoming a crucial part of health care as a method to facilitate doctor-patient interaction. Due to technological developments and the incremental acquisition of ... -
Understanding the mechanisms mediating cardi-renal benefit of empagliflozin in type 2 diabetes mellitus
Rizzo, Manfredi (2023-11)Abstract: In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type ...