Browsing by Author "Jalaleddine, Nour"
Now showing items 1-8 of 8
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ACE2 polymorphisms impact COVID-19 severity in obese patients
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2022-12)Abstract: A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. ... -
Cell free ACE2 RNA: A potential biomarker of COVID-19 severity
Jalaleddine, Nour; Hachim, Mahmood; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Despite the downward trend of COVID-19 pandemic and increased immunity of the general population, COVID19 is still an elusive disease with risks due to emerging variants. Fast and reliable diagnosis of COVID-19 ... -
Lung Epithelial Cells from Obese Patients Have Impaired Control of SARS-CoV-2 Infection
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Obesity is known to increase the complications of the COVID-19 coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms of SARSCoV-2 infection ... -
Mechanisms of SARS-CoV-2 and Male Infertility: Could Connexin and Pannexin Play a Role?
Omolaoye, Temidayo S.; Jalaleddine, Nour; Du Plessis, Stefan (2022)Abstract: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on male infertility has lately received significant attention. SARS-CoV-2, the virus that causes coronavirus disease (COVID-19) in humans, ... -
N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Kandasamy, Richard K; Al Heialy, Saba (2022)Abstract: Despite the growing number of the vaccinated population, COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global health burden. Obesity, a metabolic syndrome affecting ... -
Recent advances in vitamin D implications in chronic respiratory diseases
Jalaleddine, Nour; Al Heialy, Saba (2022)Abstract: Chronic airway inflammatory and infectious respiratory diseases are the most common medical respiratory conditions, associated with significant morbidity and mortality. Vitamin D (1,25(OH)2D3) deficiency has ... -
Simulated Microgravity Influences Immunity-Related Biomarkers in Lung Cancer
Baghoum, Hend; Alahmed, Hend; Hachim, Mahmood Yaseen; Senok, Abiola; Jalaleddine, Nour; Al Heialy, Saba (2022-12)Abstract: Microgravity is a novel strategy that may serve as a complementary tool to develop future cancer therapies. In lung cancer, the influence of microgravity on cellular processes and the migratory capacity of cells ... -
Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells
Jalaleddine, Nour; Heialy, Saba Al (2021)Abstract: Toll-like receptor 3 (TLR3) activation by viral infections plays a key role in promoting inflammatory immune responses that contribute to pulmonary fibrosis in chronic inflammatory respiratory diseases. Vitamin ...