Browsing by Author "Banerjee, Yajnavalka"
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Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence
Banerjee, Yajnavalka (2022)Abstract: Periodontitis is a microbially driven, host-mediated disease that leads to loss of periodontal attachment and resorption of bone. It is associated with the elevation of systemic inflammatory markers and with the ... -
Augmenting Flexnerism Via Twitterism: Need for Integrating Social Media Application in Blueprinting Pedagogical Strategies for Undergraduate Medical Education
Alsheikh-Ali, Alawi; Banerjee, Yajnavalka; Bayoumi, Riad (2019-03-25)Background: Flexnerism, or “competency-based medical education,” advocates that formal analytic reasoning, the kind of rational thinking fundamental to the basic sciences, especially the natural sciences, should be the ... -
Blending Gagne’s Instructional Model with Peyton’s Approach to Design an Introductory Bioinformatics Lesson Plan for Medical Students: Proof-of-Concept Study
Banerjee, Yajnavalka; Bayoumi, Riad (2018)Background: With the rapid integration of genetics into medicine, it has become evident that practicing physicians as well as medical students and clinical researchers need to be updated on the fundamentals of bioinformatics. ... -
Confronting the Challenges of Anatomy Education in a Competency-Based Medical Curriculum During Normal and Unprecedented Times (COVID-19 Pandemic): Pedagogical Framework Development and Implementation
Naidoo, Nerissa; Akhras, Aya; Banerjee, Yajnavalka (2020)Background: Anatomy is considered to be one of the keystones of undergraduate medical education. However, recently, there has been drastic reduction, both in gross anatomy teaching hours and its context. Additionally, a ... -
Counterfeit and substandard drugs in Sub-Saharan Africa may pose a major hurdle to H3Africa’s initiative to study genetics of kidney disease progression
Banerjee, Yajnavalka (2017)To the Editor: The Human Heredity and Health in Africa Kidney Disease Research Network aims to investigate the genetics of renal disease progression.1 Diabetes mellitus and hypertension have emerged as the commonest ... -
Daily Use of Extra Virgin Olive Oil with High Oleocanthal Concentration Reduced Body Weight, Waist Circumference, Alanine Transaminase, Inflammatory Cytokines and Hepatic Steatosis in Subjects with the Metabolic Syndrome: A 2-Month Intervention Study
Banerjee, Yajnavalka (2020)Abstract: Extra virgin olive oil (EVOO) intake is associated with reduced cardiovascular risk, and its phenolic compound oleocanthal (OC) has anti-oxidant and anti-inflammatory properties. The cardiometabolic effects of ... -
Design, Implementation and Evaluation of a Distance Learning Framework to Expedite Medical Education during COVID-19 pandemic: A Proof-of-Concept Study
Azar, Aida J; Hassan Khamis, Amar; Naidoo, Nerissa; Lindsbro, Marjam; Gonuguntla, Suneetha; Banerjee, Yajnavalka (2021)Background: The COVID-19 pandemic has forced medical schools to suspend on-campus live-sessions and shift to distance-learning (DL). This precipitous shift presented medical educators with a challenge, ‘to create a ... -
Design, Implementation, and Evaluation of a Distance Learning Framework to Adapt to the Changing Landscape of Anatomy Instruction in Medical Education During COVID-19 Pandemic: A Proof-of-Concept Study
Naidoo, Nerissa; Azar, Aida J; Hassan Khamis, Amar; Gholami, Mandana; Lindsbro, Marjam; Alsheikh-Ali, Alawi; Banerjee, Yajnavalka (2021)Abstract: This study presents the design of a DL-framework to deliver anatomy teaching that provides a microfiche of the onsite anatomy learning experience during the mandated COVID-19 lockdown. First, using nominal-group ... -
Diabetes and the COVID-19 Pandemic: How Insights from Recent Experience Might Guide Future Management
Banerjee, Yajnavalka (2020)Summary: In summary, the COVID-19 pandemic is a huge challenge for diabetic patients and diabetologists, but it can be also an opportunity to improve physician–patient communication for better management of the disease ... -
The Dual Pandemics of COVID-19 and Obesity: Bidirectional Impact
Banerjee, Yajnavalka (2022-08)Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has been shown to disrupt many organ systems in the human body. Though several medical disorders have been ... -
Efficient Generation of Chondrocytes From Bone Marrow–Derived Mesenchymal Stem Cells in a 3D Culture System: Protocol for a Practical Model for Assessing Anti-Inflammatory Therapies
Patnaik, Rajashree; Jannati, Shirin; Rizzo, Manfredi; Naidoo, Nerissa; Banerjee, Yajnavalka (2023)Background: Chondrocytes are the primary cells responsible for maintaining cartilage integrity and function. Their role in cartilage homeostasis and response to inflammation is crucial for understanding the progression ... -
Efficient Generation of Chondrocytes From Bone Marrow–Derived Mesenchymal Stem Cells in a 3D Culture System: Protocol for a Practical Model for Assessing Anti-Inflammatory Therapies
Patnaik, Rajashree; Jannati, Shirin; Rizzo, Manfredi; Naidoo, Nerissa; Banerjee, Yajnavalka (2023)Background: Chondrocytes are the primary cells responsible for maintaining cartilage integrity and function. Their role in cartilage homeostasis and response to inflammation is crucial for understanding the progression ... -
A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
Banerjee, Yajnavalka (2017)To the Editor: The study by Fitzgerald et al. poses the question as to whether inclisiran is suitable for long-term treatment of hyperlipidemia. In contrast with PCSK9 antibodies, which target plasma PCSK9, inclisiran ... -
Lipids derived from Camel milk regulate NLRP3 inflammasome subunit-dependent inflammatory responses in human macrophages
Banerjee, Yajnavalka (2021)Background: Camel milk is widely used for its reported anti-diabetic and health promoting effects. Lipids derived from the milk have also been shown to exhibit potent anti-inflammatory effects. The mechanism through which ... -
Liraglutide Increases Serum Levels of MicroRNA-27b, -130a and -210 in Patients with Type 2 Diabetes Mellitus: A Novel Epigenetic E ect
Banerjee, Yajnavalka (2020)Abstract: Liraglutide has shown favourable e_ects on several cardiometabolic risk factors, beyond glucose control. MicroRNAs (miRNAs) regulate gene expression, resulting in post-transcriptional modifications of cell ... -
Mento’s change model in teaching competency-based medical education
Banerjee, Yajnavalka; Tuffnell, Christopher (2019)Background: Resistance to change is customary and is expected in any organization. However, most of the downsides of change can be avoided if the organization/individual prepares for the change by acknowledging guided ... -
Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic health
Banerjee, Yajnavalka (2022)Abstract: Obesity, type 2 diabetes (T2DM), hypertension (HTN), and Cardiovascular Disease (CVD) often cluster together as “Cardiometabolic Disease” (CMD). Just under 50% of patients with CMD increased the risk of morbidity ... -
New Onset Diabetes Mellitus in COVID-19: A Scoping Review
Banerjee, Yajnavalka; Mikhailidis, Dimitri P.; Rizzo, Manfredi (2024)Background: Higher education institutions need to put change management as a pivotal part of their strategy. The challenge is to effectively contextualize existing change management models to the respective work environment. ... -
A novel 6D-approach to radically transform undergraduate medical education: preliminary reflections from MBRU
Banerjee, Yajnavalka; Azar, Aida J; Tuffnell, Christopher; Bayoumi, Riad; Davis, David A (2018-12)Background: Designers of undergraduate medical education (UME) need to address the exponentially expanding volume and variability of scientific knowledge, where by didactic teaching techniques need to be augmented by ... -
Pasta Supplemented with Opuntia ficus-indica Extract Improves Metabolic Parameters and Reduces Atherogenic Small Dense Low-Density Lipoproteins in Patients with Risk Factors for the Metabolic Syndrome: A Four-Week Intervention Study
Banerjee, Yajnavalka (2020)Abstract: Food supplementation with Opuntia ficus-indica (OFI) has been associated with a significant reduction in total cholesterol, body fat, hyperglycemia and blood pressure. Since OFI may also have antioxidant and ...