MBRU Knowledge Repository: Recent submissions
Now showing items 661-680 of 1430
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Genomic medicine in the Middle East
(2021)Abstract: We discuss the current state of genomic medicine in Arab countries of the Middle East, a region with outsized contribution to Mendelian genetics due to inbreeding yet has poor representation in global variome ... -
Flapped versus flapless alveolar ridge preservation: a systematic review and meta-analysis
(2021)Abstract: Alveolar ridge preservation (ARP) procedures can limit bone changes following tooth extraction. Flapped and flapless surgical approaches have been used for ARP; however, there is a lack of strong scientific ... -
First Report of blaCTX-M-28 in Enterobacteriaceae Isolates in the United Arab Emirates
(2018)Background: The CTX-M family of extended-spectrum beta lactamase (ESBL) enzymes is comprised of over 60 𝑏𝑙𝑎CTX-M gene variants with the predominance of 𝑏𝑙𝑎CTX-M-15 in many regions. In this report, we present the ... -
FIGO (International Federation of Gynecology and Obstetrics) initiative on fetal growth: Best practice advice for screening, diagnosis, and management of fetal growth restriction
(2021)Executive Summary: Fetal growth restriction (FGR) is defined as the failure of the fetus to meet its growth potential due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a leading cause ... -
Computational Modelling for Efficient Transdentinal Drug Delivery
(2017)Abstract: This work deals with the numerical investigation of the delivery of potential therapeutic agents through dentinal discs (i.e., a cylindrical segment of the dentinal tissue) towards the dentin–pulp junction. The ... -
Comprehensive Treatment of Severe Periodontal and Periimplant Bone Destruction Caused by Iatrogenic Factors
(2018)Introduction: Dental implant success requires placement after periodontal therapy, with adequate bone volume, plaque control, primary stability, control of risk factors, and use of well-designed prostheses. ,is report ... -
Clinical outcomes of single implant supported crowns versus 3‑unit implant‑supported fixed dental prostheses in Dubai Health Authority: a retrospective study
(2021)Background: This study assessed retrospectively the clinical outcomes of single implant-supported crowns and implant-supported fixed dental prostheses (FDPs). Methods: This case series compared biological and technical ... -
Cross-Nation Comparison of Oral Cancer in the Eastern Mediterranean Region: an Ecological Overview
(2015)Abstract: Eastern Mediterranean (EM) region countries include countries from the Mediterranean region and North Africa representing regions with wide variations in their politics, economy, peaceful status, and healthcare ... -
COVID-19 and the Heart: A Systematic Review of Cardiac Autopsies
(2021)Importance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated cardiac injury has been postulated secondary to several mechanisms. While tissue diagnosis is limited during the acute illness, postmortem ... -
Could COVID-19 Trigger a Rebirth in Anatomy Education? A Glimpse of Anatomists’ Responses to Pandemics of the Past and Present
(2021)Abstract: Pandemics are nothing unusual but indeed lead to devastating effects that play a pivotal role in reshaping human history. The COVID-19 outbreak is currently responsible for major educational crises globally as ... -
Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target
(2017)Abstract: Cytochrome P450-mediated metabolism of arachidonic acid (AA) is an important pathway for the formation of eicosanoids. The !-hydroxylation of AA generates significant levels of 20-hydroxyeicosatetraenoic acid ... -
Changes in skin blood flow, respiration and blood pressure in participants reporting motion sickness during sinusoidal galvanic vestibular stimulation
(2019)Abstract: We tested the hypothesis that galvanic vestibular stimulation, which produces illusions of side-to side swaying, causes a greater reduction in skin blood flow in participants who report stimulation induced nausea. ... -
Case Report: Expanding the Phenotypic Spectrum of Timothy Syndrome Type 1: A Sporadic Case With a de novo CACNA1C Pathogenic Variant and Segmental Ileal Dilatation
(2021)Background: Long QT syndactyly syndrome (long QT syndrome type 8), also known as Timothy Syndrome (TS) was first described in 1994 with still <50 case reported in the literature. The full spectrum of the syndrome is not ... -
Case Report: BCG-Triggered Hemophagocytic Lymphohistiocytosis in an Infant With X-Linked Recessive Mendelian Susceptibility to Mycobacterial Disease Due to a Variant of Chronic Granulomatous Disease
(2021)Abstract: In the United Arab Emirates, BCG (Bacillus Calmette-Guérin) is administered to all newborns. We present here a young infant with an inborn error of immunity (IEI) who developed fatal adverse events to this ... -
Case Report: A Case of Leukocyte Adhesion Deficiency, Type III Presenting With Impaired Platelet Function, Lymphocytosis and Granulocytosis
(2021)Abstract: Fermitin family homolog 3 (FERMT3), alternatively kindlin-3 (KIND3), is an integrin binding protein (of 667 residues) encoded by the FERMT3 gene. The molecule is essential for activating integrin aIIbb3 (the ... -
CART Cell Toxicities: New Insight into Mechanisms and Management
(2020)Abstract: T cells genetically engineered with chimeric antigen receptors (CART) have become a potent class of cancer immunotherapeutics. Numerous clinical trials of CART cells have revealed remarkable remission rates in ... -
Cardiac Screening To Mitigate The Risk Of Sudden Cardiac Death In Middle Eastern And African Competitive Athletes. A Systematic Review
(2020)Objective: The study aims to review the literature regarding abnormalities predisposing to Sudden Cardiac Death (SCD) in young Middle Eastern and African competitive athletes between the years 2009e2019 and aims to assess ... -
Elements that underpin the design, development and evaluation of social media health interventions. A Scoping Review Protocol
(2021)Background: Social media use has grown tremendously over the years. Given the volume of people on social media and the amount of information being exchanged, it is perhaps unsurprising that social media is being used to ... -
A systematic review and meta-analysis of primary teeth caries studies in Gulf Cooperation Council States
(2018)Objectives: The aim of the study was to evaluate the prevalence and severity of dental caries in pre-school children in the Gulf Cooperation Council (GCC) area. Methods: A search of literature was conducted to identify ... -
3D bioprinting for in vitro models of oral cancer: Toward development and validation
(2021)Abstract The tumor microenvironment (TME) of oral carcinomas has highly complex contents and a dynamic nature which is difficult to study using oversimplified two-dimensional (2D) cell culture systems. By contrast, three ...