MBRU Knowledge Repository: Recent submissions
Now showing items 1301-1320 of 1430
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Development of a national Department of Veterans Affairs mortality risk prediction model among patients with cirrhosis
(2019)Objective: Cirrhotic patients are at high hospitalization risk with subsequent high mortality. Current risk prediction models have varied performances with methodological room for improvement. We used current analytical ... -
Artificial intelligence for precision medicine in neurodevelopmental disorders
(2019)Abstract: The ambition of precision medicine is to design and optimize the pathway for diagnosis, therapeutic intervention, and prognosis by using large multidimensional biological datasets that capture individual variability ... -
An anthropometric evaluation of the scapula, with emphasis on the coracoid process and glenoid fossa in a South African population
(2019)Abstract: The exact dimensions of the scapula, including the coracoid process and glenoid fossa, are fundamental in the patho-mechanics of the glenohumeral joint (GHJ); as these structures act as initiators of shoulder ... -
Demystifying Smoker’s Paradox: A Propensity Score–Weighted Analysis in Patients Hospitalized With Acute Heart Failure
(2019)Background: Smoker’s paradox has been observed with several vascular disorders, yet there are limited data in patients with acute heart failure (HF). We examined the effects of smoking in patients with acute HF using data ... -
Searching for Atrial Fibrillation Poststroke A White Paper of the AF-SCREEN International Collaboration
(2019)Abstract: Cardiac thromboembolism attributed to atrial fibrillation (AF) is responsible for up to one-third of ischemic strokes. Stroke may be the first manifestation of previously undetected AF. Given the efficacy of oral ... -
Granulomatous hypophysitis: rare disease with challenging diagnosis
(2017)Abstract: Granulomatous hypophysitis is rare pathology that mimics pituitary adenoma. Diagnosis is only confirmed by histopathology examination. Trans-sphenoidal surgery is considered diagnostic when descent tissue specimen ... -
Analysis of blood donor pre-donation deferral in Dubai: Characteristics and reasons
(2017)Background: To ensure an adequate and safe blood supply, it is crucial to select suitable donors according to stringent eligibility criteria. Understanding the reasons for donor deferral can help in planning more efficient ... -
An arthroscopic evaluation of the anatomical “critical zone”
(2017)Background: The “critical zone”, a region of speculated vascularity, is situated approximately 10 mm proximal to the insertion of the supraspinatus tendon. De-spite its obvious role as an anatomical landmark demarcator, ... -
Genetic loci associated with heart rate variabilityand their effects on cardiac disease risk
(2017)Abstract: Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for ... -
Positive selection of lactase persistence among people of Southern Arabia
(2016-08-04)Objective: Frequency patterns of the lactase persistence (LP)-associated 213,915 G allele and archaeological records pointing to substantial role played by southern regions in the peopling and domestication processes that ... -
An anatomical investigation of the carotid canal
(2017)Background: The carotid canal (CC) located in the petrous temporal bone trans-mits the internal carotid artery, internal carotid venous plexus and sympathetic nerve plexus from the neck into the cranial cavity. It is an ... -
Taxonomy of the order Mononegavirales: update 2016
(2016-05-23)Abstract: In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), ... -
Diagnostic accuracy of QuickVue® Dipstick Strep A test and its effect on antibiotic prescribing in children in the United Arab Emirates
(2019)Background: Unnecessary antibiotic prescription to patients with upper respiratory tract infections (URTIs) has led to the increase in antibiotics resistant bacteria rates. In this study, we evaluated the diagnostic accuracy ... -
A novel HRM assay for the simultaneous detection and differentiation of eight poxviruses of medical and veterinary importance
(2017-02-20)Abstract: Poxviruses belonging to the Orthopoxvirus, Capripoxvirus and Parapoxvirus genera share common host species and create a challenge for diagnosis. Here, we developed a novel multiplex PCR method for the simultaneous ... -
Characterisation of a novel SCCmec VI element harbouring fusC in an emerging Staphylococcus aureus strain from the Arabian Gulf region
(2019)Fusidic acid is a steroid antibiotic known since the 1960s. It is frequently used in topical preparations, i.e., ointments, for the treatment of skin and soft tissue infections caused by Staphylococcus aureus. There is an ... -
Possibility and Challenges of Conversion of Current Virus Species Names toLinnaean Binomials
(2017-05-01)Botanical, mycological, zoological, and prokaryotic species names follow the Linnaean format, consisting of anitalicized Latinized binomen with a capitalized genus name and a lower case species epithet (e.g.,Homo sapiens). ... -
“I Must Try Harder”: Design Implications for Mobile Apps and Wearables Contributing to Self-Efficacy of Patients With Chronic Conditions
(2019)Background: Diverse wellness-promoting mobile health technologies, including mobile apps and wearable trackers, became increasingly popular due to their ability to support patients’ self-management of health conditions. ... -
No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses
(2019)Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the family Flaviviridae. However, apart from a single case of vertical transmission, natural routes of EqHV transmission ... -
1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice
(2019)More than 90% of human pancreatic cancers carry the oncogenic mutant of Ki-RAS and their growth depends on its downstream kinase PAK1, mainly because PAK1 blocks the apoptosis of cancer cells selectively. We developed a ...