MBRU Knowledge Repository: Recent submissions
Now showing items 1261-1280 of 1430
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West Nile virus in overwintering mosquitoes, central Europe
(2017-10-02)Background: West Nile virus (WNV) is currently the most important mosquito-borne pathogen spreading in Europe. Data on overwintering of WNV in mosquitoes are crucial for understanding WNV circulation in Europe; nonetheless, ... -
Usutu virus, Austria and Hungary, 2010-2016.
(2017)Abstract: Usutu virus (USUV,Flaviviridae) was first reported in Europe in Austria in 2001, where it caused wild bird (mainly black bird) mortality until 2005. Since 2006 no further USUV cases were diagnosed in the country. ... -
Usutu virus infections among blood donors, Austria, july and august 2017 – Raising awareness for diagnostic challenges
(2017-10)Abstract: Between July and August 2017, seven of 12,047 blood donations from eastern Austria, reacted positive to West Nile virus (WNV) in the cobas test (Roche). Follow-up investigations ... -
Rates, Distribution, and Implications of Post-zygotic Mosaic Mutations in Autism Spectrum Disorder
(2017-09)Abstract: We systematically analyzed post-zygotic mutations (PZMs) in whole-exome sequences from the largest collection of trios (5,947) with autism spectrum disorder (ASD) available, including 282 unpublished trios, and ... -
BMI is inversely correlated to the risk of mortality in patients with type 2 diabetes hospitalized for acute heart failure: Findings fromthe Gulf aCute heArt failuRE (Gulf-CARE) registry.
(2017-02-27)Background: A U-shaped relationship has been reported between BMI and cardiovascular events among patients with acute heart failure (AHF). We hypothesized that an obesity paradox also governs the relationship between BMI ... -
β-Blocker therapy prior to admission for acute coronary syndrome in patients without heart failure or left ventricular dysfunction improves in-hospital and 12-Month Outcome: Results from the GULF-RACE 2 (Gulf Registry of Acute Coronary Events-2)
(2017-11-14)Background: The prognostic impact of b-blockers (BB) in acute coronary syndrome (ACS) patients without heart failure (HF) or left ventricular dysfunction is controversial, especially in the postreperfusion era. We sought ... -
Vector prevalence and detection of crimean-congo haemorrhagic fever virus in Golestan province, Iran
(2017-12)Background & Objectives: Crimean-Congo haemorrhagic fever virus (CCHFV) causes severe disease with fatality rate of 30%. The virus is transmitted to humans through the bite of an infected tick, direct contact with the ... -
Mortality and Morbidity in HFrEF, HFmrEF, and HFpEF Patients with Diabetes in the Middle East
(2020)Objectives: We sought to estimate the mortality and morbidity in diabetic acute heart failure (AHF) patients stratified by left ventricular ejection fraction. Methods: We analyzed the data of patients with AHF from ... -
A Serological Protein Microarray for Detection of Multiple Cross-Reactive Flavivirus Infections in Horses for Veterinary and Public Health Surveillance
(2017)Abstract: The genus Flavivirus in the family Flaviviridae includes some of the most important examples of emerging zoonotic arboviruses that are rapidly spreading across the globe. Japanese encephalitis virus (JEV), West ... -
Germline and somatic mutations in STXBP1 with diverse neurodevelopmental phenotypes
(2017-08-30)Objective: To expand the clinical phenotype associated with STXBP1 gene mutations and to understand the effect of STXBP1 mutations in the pathogenesis of focal cortical dysplasia (FCD). Methods: Patients with STXBP1 ... -
Investigating the job satisfaction of healthcare providers at primary healthcare centres in Lebanon: A national cross-sectional study
(2017-04-11)Abstract: Low job satisfaction is linked to higher staff turnover and intensified shortages in healthcare providers (HCP). This study investigates the level of, and factors associated with, HCP job satisfaction in the ... -
Genipin attenuates cisplatin-induced nephrotoxicity by counteracting oxidative stress, inflammation, and apoptosis
(2017-07-05)Abstract: Cisplatin (CP) is a potent and widely used chemotherapeutic agent. However, the clinical benefits of CP are compromised because it elicits nephrotoxicity and ototoxicity. In this study, we investigated the ... -
Precision MedicineWhere have we reached and where are we headed?
(2017-09-25)Conclusion: The journey to personalised cancer treatment continues and, happily, this goal may no longer be quite so elusive. The advent of immunohistochemistry and monoclonal antibodies were torchbearers for tailored ... -
The workforce trends of nurses in Lebanon (2009–2014): A registration database analysis.
(2017-08-11)Background: Analysis of the nursing registration databases is a highly informative approach that provides accurate and reliable information supporting evidence based decisions relevant to the nursing workforce planning, ... -
The paradox of falling job satisfaction withrising job stickiness in the German nursingworkforce between 1990 and 2013
(2017-08-29)Background: Literature reports a direct relation between nurses’ job satisfaction and their job retention (stickiness). The proper planning and management of the nursing labor market necessitates the understanding of job ... -
Systolic Blood Pressure on Admissionand Mortality in Patients HospitalizedWith Acute Heart Failure: ObservationsFrom the Gulf Acute Heart Failure Registry
(2017)Abstract: We investigated the role of systolic blood pressure (SBP) in relation to in-hospital and postdischarge mortality in patients admitted with acute heart failure (AHF). The SBP of 4848 patients aged 18 years admitted ... -
Lipoprotein(a) Induces Human Aortic Valve Interstitial Cell Calcification
(2017-03-30)Abstract: Lipoprotein(a), or Lp(a), significantly increased alkaline phosphatase activity, release of phosphate, calcium deposition, hydroxyapatite, cell apoptosis, matrix vesicle formation, and phosphorylation of signal ... -
Taxonomy of the order Mononegavirales: update 2017
(2017-04-07)Abstract: In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel species. Five new rhabdovirus genera and one new nyamivirus genus were established to harbor 41 of these species, whereas ... -
Detection of Clostridium difficile antigen and toxin in stool specimens: Comparison of the C. difficile quik chek complete enzyme immunoassay and GeneXpert C. difficile polymerase chain reaction assay
(2017)Background/Aims: Accurate and rapid laboratory diagnosis of Clostridium difficile infections (CDI) remains a significant challenge. A two‑step algorithm for detection of toxigenic C. difficile in stool based on initial ... -
Vestibular Modulation of Sympathetic Nerve Activity to Muscle and Skin in Humans
(2017-07-26)Abstract: We review the existence of vestibulosympathetic reflexes in humans. While several methods to activate the human vestibular apparatus have been used, galvanic vestibular stimulation (GVS) is a means of selectively ...