MBRU Knowledge Repository: Recent submissions
Now showing items 1221-1240 of 1430
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Genotyping of Staphylococcus aureus associated with nasal colonization among healthcare workers using DNA microarray
(2018-05)Introduction: Healthcare workers (HCWs) colonized with Staphylococcus aureus may serve as a reservoir of infection. This study was carried to determine the genetic make-up of S. aureusnasal colonizers in HCWs. Method ... -
Learning from the Law. A review of 21 years of litigation for pain during caesarean section
(2018)Abstract: The large majority of caesarean sections in the UK are now carried out under neuraxial anaesthesia. Although this technique is widely accepted as being the safest option in most circumstances, the use of regional ... -
The relationship between thalamic GABA content and resting cortical rhythm in neuropathic pain
(2018-01)Abstract: Recurrent thalamocortical connections are integral to the generation of brain rhythms and it is thought that the inhibitory action of the thalamic reticular nucleus is critical in setting these rhythms. Our work ... -
Genomic Context Analysis of de Novo STXBP1 Mutations Identifies Evidence of Splice Site DNA-Motif Associated Hotspots
(2018-02-22)Abstract: Mutations withinSTXBP1have been associated with a range of neuro developmental disorder simplicating the pleotropic impact of this gene. Although the frequency of de novo mutations withinSTXBP1for selective ... -
Identification of early indicators of altered metabolism in normal development using a rodent model system
(2018-03-01)Abstract: Although the existence of a close relationship between the early maternal developmental environment, fetal size at birth and the risk of developing disease in adulthood has been suggested, most studies,however, ... -
The metaboreflex does not contribute to the increase in muscle sympathetic nerve activity to contracting muscle during static exercise in humans
(2018-01-08)Abstract: Both central command and metaboreflex inputs from contracting muscles increase muscle sympathetic nerve activity (MSNA) to non-contracting muscle during sustainedisometric exercise. We recently showed that MSNA ... -
Self-Reported Prevalence of Endometriosis and its Symptoms in the United Arab Emirates (UAE)
(2018-03)Abstract: The true prevalence and risk factors for endometriosis among women in UAE are unknown. Objectives: To estimate the prevalence of endometriosis among women in UAE aged 18 to 55 years, risk factors and related ... -
A double-blind placebo-controlled clinical investigation into pain reduction effect of placing the pain spot outside the intersection area of the two currents of interferential therapy compared to traditional method
(2018-01-26)Background: Interferential therapy (IFT) is applied to intersect in the painful area but no confirmed effect with this method. Experimentally, the highest voltage of IFT is induced outside the intersection of the two ... -
Predictors of Shoulder Degeneration in the KwaZulu-Natal Population of South Africa
(2018-03)Abstract: The critical shoulder angle and acromion index are conventional radiological tools employed as predictors of shoulder degeneration. As they represent the static components of glenohumeral stability, the ... -
Muscle sympathetic nerve activity-coupled changes in brain activity during sustained muscle pain
(2018-02-07)Introduction: Long-lasting experimental muscle pain elicits divergent muscle sympathetic responses, with some individuals exhibiting a persistent increase in muscle sympathetic nerve activity (MSNA), and others a decrease. ... -
Spatial and Phylodynamic Survey on Crimean-Congo Hemorrhagic Fever Virus Strains in Northeast of Iran
(2018-01-29)Background: Crimean-Congo hemorrhagic fever (CCHF) is asymptomatic in infected animals, yet the virus poses a serious threat to humans causing a symptomatic, hemorrhagic disease with a high case-fatality rate. Numerous ... -
Factors Affecting Transmission of Crimean - Congo Hemorrhagic Fever among Slaughterhouse Employees: A Serosurvey in Mashhad, Iran
(2018-02-12)Background: Crimean - Congohemorrhagic fever (CCHF) is a severe viral disease. Slaughterhouses are potentially high risk working environments for CCHF infection due to close contact of livestock and humans. Objectives: The ... -
Nootkatone confers hepatoprotective and anti-fibrotic actions in amurine model of liver fibrosis by suppressing oxidative stress, inflammation, and apoptosis
(2017-11-20)Abstract: In this study, the hepatoprotective and anti-fibrotic actions of nootkatone (NTK) were investigated using carbon tetrachloride (CCl4)-induced liver fibrosis in mice. CCl4 administration elevated serum aspartate ... -
Founder mutation in IKBKAP gene causes vestibular impairment in familial dysautonomia
(2018)Objective: To assess vestibular function in patients with familial dysautonomia (FD), a hereditary sensory and autonomic neuropathy – caused by a mutation in the IKBKAP gene (c.2204 + 6 T > C) – and characterized by marked ... -
OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
(2018-02-01)Abstract: Copy-number variations (CNVs) are strong risk factors for neurodevelopmental and psychiatric disorders. The 15q13.3 microdeletion syndrome region contains up to ten genes and is associated with numerous conditions, ... -
Cardiovascular risk factor burden in Africa and the Middle East across country income categories: a post hoc analysis of the cross-sectional Africa Middle East Cardiovascular Epidemiological (ACE) study
(2018-02-12)Background: A significant number of cardiovascular disease (CVD)-related deaths occur in developing countries. An increasing prevalence of CVD is associated with a change in the macro-economy of these countries. In this ... -
Acute heart failure presentations and outcomes during the fasting month of Ramadan: an observational report from seven Middle Eastern countries
(2018)Background: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic ... -
Incidence and impact of cardiorenal anaemia syndrome on all-cause mortality in acute heart failure patients stratified by left ventricular ejection fraction in the Middle East
(2018-10-12)Aims: This study aims to evaluate the incidence and impact of cardiorenal anaemia syndrome (CRAS) on all-cause mortality in acute heart failure (AHF) patients stratified by left ventricular ejection fraction (LVEF) status ... -
Maternal and birth cohort studies in the Gulf Cooperation Council countries: protocol for a systematic review and narrative evaluation
(2018)Introduction: Cohort studies have revealed that genetic, socioeconomic, communicable and noncommunicable diseases, and environmental exposures during pregnancy may influence the mother and her pregnancy, birth delivery ... -
Association of IMMP2L deletions with autism spectrum disorder: A trio family study and meta-analysis
(2018)Abstract: IMMP2L, the gene encoding the inner mitochondrial membrane peptidase subunit 2- like protein, has been reported as a candidate gene for Tourette syndrome, autism spectrum disorder (ASD) and additional ...