Browsing Faculty Publications (CoM) by Author "Senok, Abiola"
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ACE2 polymorphisms impact COVID-19 severity in obese patients
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2022-12)Abstract: A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination programs. ... -
Cell free ACE2 RNA: A potential biomarker of COVID-19 severity
Jalaleddine, Nour; Hachim, Mahmood; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Despite the downward trend of COVID-19 pandemic and increased immunity of the general population, COVID19 is still an elusive disease with risks due to emerging variants. Fast and reliable diagnosis of COVID-19 ... -
Clinical Impact of the BIOFIRE Blood Culture Identification 2 Panel in Adult Patients with Bloodstream Infection: A Multicentre Observational Study in the United Arab Emirates
Senok, Abiola; Olowoyeye, Victory (2023)Abstract: Rapid pathogen identification is key to the proper management of patients with bloodstream infections (BSIs), especially in the intensive care setting. This multicentre study compared the time to pathogen ... -
Clinical Impact of the BIOFIRE Blood Culture Identification 2 Panel in Adult Patients with Bloodstream Infection: A Multicentre Observational Study in the United Arab Emirates
Senok, Abiola; Olowoyeye, Victory (2023)Abstract: Rapid pathogen identification is key to the proper management of patients with bloodstream infections (BSIs), especially in the intensive care setting. This multicentre study compared the time to pathogen ... -
Coinfections in Patients Hospitalized with COVID-19: A Descriptive Study from the United Arab Emirates
Senok, Abiola; Nassar, Rania; Hachim, Mahmood Yaseen; Al Suwaidi, Hanan; Alsheikh-Ali, Alawi (2021)Purpose: Microbial coinfections in COVID-19 patients carry a risk of poor outcomes. This study aimed to characterize the clinical and microbiological profiles of coinfections in patients with COVID-19. Methods: A ... -
COVID-19 Transcriptomic Atlas: A Comprehensive Analysis of COVID-19 Related Transcriptomics Datasets
Alqutami, Fatma; Senok, Abiola; Hachim, Mahmood Yaseen (2021)Background: To develop anti-viral drugs and vaccines, it is crucial to understand the molecular basis and pathology of COVID-19. An increase in research output is required to generate data and results at a faster rate, ... -
Detection of Clostridium difficile antigen and toxin in stool specimens: Comparison of the C. difficile quik chek complete enzyme immunoassay and GeneXpert C. difficile polymerase chain reaction assay
Senok, Abiola (2017)Background/Aims: Accurate and rapid laboratory diagnosis of Clostridium difficile infections (CDI) remains a significant challenge. A two‑step algorithm for detection of toxigenic C. difficile in stool based on initial ... -
Effect of Common Medications on the Expression of SARS-CoV-2 Entry Receptors in Kidney Tissue
Tayoun, Ahmad Abou; Loney, Tom; Uddin, Mohammed; Senok, Abiola; Al Heialy, Saba; Alsheikh-Ali, Alawi (2020)Abstract: Besides the respiratory system, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection was shown to affect other essential organs such as the kidneys. Early kidney involvement during the course ... -
An emerging Panton-Valentine leukocidin (PVL)-positive CC5-meticillin-resistant Staphylococcus aureus-IVc clone recovered from hospital and community settings over a 17-year period from 12 countries investigated by whole-genome sequencing
Senok, Abiola (2022-12)Background: A novel Panton-Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC)5-MRSA-IVc ('Sri Lankan' clone) was recently described from Sri Lanka. Similar isolates ... -
First Report of blaCTX-M-28 in Enterobacteriaceae Isolates in the United Arab Emirates
Senok, Abiola (2018)Background: The CTX-M family of extended-spectrum beta lactamase (ESBL) enzymes is comprised of over 60 𝑏𝑙𝑎CTX-M gene variants with the predominance of 𝑏𝑙𝑎CTX-M-15 in many regions. In this report, we present the ... -
Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease
Loney, Tom; Al Suwaidi, Hanan; Uddin, Mohammed; Senok, Abiola; Nowotny, Norbert; Alsheikh-Ali, Alawi; Tayoun, Ahmad Abou (2021)Abstract: The geographic location and heterogeneous multi-ethnic population of Dubai (United Arab Emirates; UAE) provide a unique setting to explore the global molecular epidemiology of SARS-CoV-2 and relationship between ... -
Genotyping of methicillin resistant Staphylococcus aureus from the United Arab Emirates
Senok, Abiola; Nassar, Rania (2020)Abstract: Reports from Arabian Gulf countries have demonstrated emergence of novel methicillin resistant Staphylococcus aureus (MRSA) strains. To address the lack of data from the United Arab Emirates (UAE), genetic ... -
Genotyping of Staphylococcus aureus associated with nasal colonization among healthcare workers using DNA microarray
Senok, Abiola (2018-05)Introduction: Healthcare workers (HCWs) colonized with Staphylococcus aureus may serve as a reservoir of infection. This study was carried to determine the genetic make-up of S. aureusnasal colonizers in HCWs. Method ... -
Healthcare Derived Smart Watches and Mobile Phones are Contaminated Niches to Multidrug Resistant and Highly Virulent Microbes
Boucherabine, Syrine; Nassar, Rania; Mohamed, Lobna; Alqutami, Fatma; Zaher, Shroque; Hachim, Mahmood Yaseen; Senok, Abiola (2022)Background: As high touch wearable devices, the potential for microbial contamination of smart watches is high. In this study, microbial contamination of smart watches of healthcare workers (HCWs) was assessed and compared ... -
Investigating a rare methicillin-resistant Staphylococcus aureus strain: first description of genome sequencing and molecular characterization of CC15-MRSA
Senok, Abiola (2017-10-04)Purpose: Methicillin resistant Staphylococcus aureus CC15 strains (CC15-MRSA) have only been sporadically described in literature. This study was carried out to describe the genetic make-up for this rare MRSA strain. Methods: ... -
Lateral Flow Immunoassay for the Detection of Panton-Valentine Leukocidin in Staphylococcus aureus From Skin and Soft Tissue Infections in the United Arab Emirates
Senok, Abiola; Nassar, Rania; Celiloglu, Handan (2021)Introduction: Panton Valentine leukocidin (PVL) is a virulence factor which is associated with methicillin sensitive and resistant Staphylococcus aureus (MSSA/MRSA) causing skin and soft tissue infections (SSTI). This ... -
Leveraging the Added Value of Experiential Co-Curricular Programs to Humanize Medical Education
Senok, Abiola; John-Baptiste, Anne-Marie; Heialy, Saba Al; Naidoo, Nerissa; Otaki, Farah; Davis, Dave (2021)Background: The aftermath of the 1910 Flexner report resulted in significant gaps in the structure of medical education. Experiential co-curricular opportunities can contribute to addressing these gaps. Purpose: To ... -
Lung Epithelial Cells from Obese Patients Have Impaired Control of SARS-CoV-2 Infection
Jalaleddine, Nour; Hachim, Mahmood Yaseen; Senok, Abiola; Al Heialy, Saba (2023)Abstract: Obesity is known to increase the complications of the COVID-19 coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms of SARSCoV-2 infection ... -
Metagenomic Sequencing and Reverse Transcriptase PCR Reveal That Mobile Phones and Environmental Surfaces Are Reservoirs of Multidrug-Resistant Superbugs and SARS-CoV-2
Boucherabine, Syrine; Nassar, Rania; Zaher, Shroque; Mohamed, Lobna; Alqutami, Fatma; Hachim, Mahmood Yaseen; Senok, Abiola (2022)Background: Mobile phones of healthcare workers (HCWs) can act as fomites in the dissemination of microbes. This study was carried out to investigate microbial contamination of mobile phones of HCWs and environmental ... -
Mobile phones are hazardous microbial platforms warranting robust public health and biosecurity protocols
Nassar, Rania; Senok, Abiola (2022)Introduction: Advancements in technology and communication have revolutionised the twenty-frst century with the introduction of mobile phones and smartphones. These phones are known to be platforms harbouring microbes ...